Publications
463 results found
Miller CA, O'Hanlon R, Prasad SK, 2009, Diagnosis of Acute Myocarditis by Cardiovascular Magnetic Resonance in a Patient With Chest Pain, Positive Troponin, and Normal Coronary, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol: 55, Pages: 74-74, ISSN: 0735-1097
Carpenter J-P, Prasad SK, Pennell DJ, 2009, Myocardial fibrosis in thalassaemia: recalling the past or telling the future?, HEART, Vol: 95, Pages: 1646-1647, ISSN: 1355-6037
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- Citations: 3
Locca D, Jeanrenaud X, Schwitter J, et al., 2009, [Cardiomyopathy and cardiac magnetic resonance]., Rev Med Suisse, Vol: 5, Pages: 2051-2057, ISSN: 1660-9379
Cardiovascular magnetic resonance (CMR) is a rapidly emerging non-invasive imaging technique free of X-Ray and offers higher spatial resolution than alternative forms of cardiac imaging for the assessment of left ventricular (LV) anatomy, function, and viability due to the unique capability of myocardial tissue characterization after gadolinium-chelates contrast administration. This imaging technique has clinical utility over a broad spectrum of heart diseases: ranging from ischaemic to non ischaemic aetiologies. Cardiomyopathies (CMP) are a heterogeneous group of diseases of the myocardium associated with architectural abnormalities and mechanical dysfunction. CMR can help excluding coronary artery disease and can provide positive diagnostic features for several CMP resulted in better diagnosis and management, Leading to improvements in mortality.
Locca D, Ferrante G, Bucchiarelli-Ducci CH, et al., 2009, Background. Cardiac Magnetic Resonance Imaging (CMR) can identify myocardial damage due to embolization after percutaneous coronary interventions (PCI). Late Gadolinium Enhancement (LGE) can non-invas, EUROPEAN HEART JOURNAL, Vol: 30, Pages: 525-525, ISSN: 0195-668X
O'Hanlon R, Whyte GP, Smith G, et al., 2009, Evaluation of myocardial damage by cardiac MRI following troponin positive endurance exercise, EUROPEAN HEART JOURNAL, Vol: 30, Pages: 853-853, ISSN: 0195-668X
Maceira Gonzalez AM, Cosin-Sales J, Prasad SK, et al., 2009, Changes in atrial function with age. Cardiovascular magnetic resonance study in healthy volunteers, EUROPEAN HEART JOURNAL, Vol: 30, Pages: 954-955, ISSN: 0195-668X
O'Hanlon R, Bucciarelli-Ducci C, Grasso A, et al., 2009, Myocardial fibrosis as an independent predctor of atrial fibrillation in HCM. A cardiovascular magnetic resonance study, EUROPEAN HEART JOURNAL, Vol: 30, Pages: 181-182, ISSN: 0195-668X
Gulati A, Chan C, Viertel A, et al., 2009, Quadricuspid Aortic Valve: The Four-Leaf Clover Discovered by Cardiac MRI, JOURNAL OF HEART VALVE DISEASE, Vol: 18, Pages: 583-584, ISSN: 0966-8519
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- Citations: 3
Maron MS, Olivotto I, Maron BJ, et al., 2009, The Case for Myocardial Ischemia in Hypertrophic Cardiomyopathy, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol: 54, Pages: 866-875, ISSN: 0735-1097
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- Citations: 197
Wilson M, O'Hanlon R, Prasad S, et al., 2009, Myocardial fibrosis in an veteran endurance athlete, BMJ Case Reports
This study reports the cardiac structure and function of a lifelong male endurance athlete, who has run over 148 000 miles, who presented with symptoms of chest discomfort, dyspnoea and loss of competitive running performance. Importantly, the athlete documented several periods of regular intensive endurance activity while suffering with flu-like symptoms. Cardiovascular MRI demonstrated a pattern of late gadolinium enhancement, which indicated myocardial scarring as a result of previous myocarditis. Myocarditis is a non-ischaemic inflammatory disease of the myocardium associated with cardiac dysfunction and arrhythmogenic substrate. The clinical course of viral myocarditis is mostly insidious with limited cardiac inflammation and dysfunction. However, as in the present case, overwhelming inflammation may occur in a subset of patients leading to myocardial fibrosis due to recurrent inflammation.
Sarwar R, Petretto E, Grieve IC, et al., 2009, INTEGRATED GENOMICS APPROACHES IDENTIFY OSTEOGLYCIN AS A REGULATOR OF LEFT VENTRICULAR MASS, Annual Scientific Conference of the British-Cardiovascular-Society, Publisher: B M J PUBLISHING GROUP, Pages: A4-A4, ISSN: 1355-6037
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- Citations: 2
Friedrich MG, Sechtem U, Schulz-Menger J, et al., 2009, Cardiovascular magnetic resonance in myocarditis: A JACC White Paper., J Am Coll Cardiol, Vol: 53, Pages: 1475-1487
Cardiovascular magnetic resonance (CMR) has become the primary tool for noninvasive assessment of myocardial inflammation in patients with suspected myocarditis. The International Consensus Group on CMR Diagnosis of Myocarditis was founded in 2006 to achieve consensus among CMR experts and develop recommendations on the current state-of-the-art use of CMR for myocarditis. The recommendations include indications for CMR in patients with suspected myocarditis, CMR protocol standards, terminology for reporting CMR findings, and diagnostic CMR criteria for myocarditis (i.e., "Lake Louise Criteria").
Sen-Chowdhry S, Syrris P, Prasad SK, et al., 2009, Left Dominant Arrhythmogenic Cardiomyopathy A New Clinical Entity Without a Typical Substrate of Myocardial Damage Reply, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol: 53, Pages: 1571-1572, ISSN: 0735-1097
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- Citations: 2
Sa MI, Kiesewetter CH, Jagathesan R, et al., 2009, Acute Pericarditis Assessed With Magnetic Resonance Imaging A New Approach, CIRCULATION, Vol: 119, Pages: E183-E186, ISSN: 0009-7322
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- Citations: 10
Whyte G, Sheppard M, George K, et al., 2009, Post-mortem evidence of idiopathic left ventricular hypertrophy and idiopathic interstitial myocardial fibrosis: Is exercise the cause?, BMJ Case Reports
We report the case of an experienced, highly trained marathon runner who died suddenly while running. On post-mortem examination, left ventricle hypertrophy and idiopathic interstitial myocardial fibrosis was found. We believe that life-long, repetitive bouts of arduous physical activity resulted in fibrous replacement of the myocardium, causing a pathological substrate for the propagation of fatal arrhythmias.
Alpendurada F, O'Hanlon R, Prasad SK, 2009, Cardiovascular magnetic resonance of cardiomyopathies., Curr Cardiol Rep, Vol: 11, Pages: 61-69
Cardiomyopathies are a heterogeneous group of diseases of the myocardium associated with architectural abnormalities and mechanical dysfunction. Recent advances in our understanding of the genetics, pathophysiology, and natural history of these conditions has resulted in better diagnosis and management, leading to improvements in mortality. Major developments in imaging techniques, in particular contrast-enhanced MRI, now permit in vivo tissue characterization of the myocardium. Through defining disease severity, etiology, and to some extent in risk stratification, routine cardiovascular magnetic resonance evaluation of this group of patients provides essential information required in everyday clinical practice.
Ball MJ, Keenan N, Lynch M, et al., 2009, Identifying the aetiology of left ventricular hypertrophy in an athlete: importance of lifestyle modification., BMJ Case Rep, Vol: 2009
The aetiology of left ventricular hypertrophy (LVH) in an athlete is often difficult to identify. We describe a 29-year-old fitness instructor who was referred for investigation of syncope. He gave a history of intensive weight lifting and anabolic steroid use at supra-therapeutic doses for the preceding 6 years. Electrocardiography showed inferolateral repolarisation abnormalities and a transthoracic echocardiogram demonstrated asymmetrical LVH with reduced left ventricular cavity dimensions. There was no left ventricular outflow tract obstruction or systolic motion of the anterior mitral valve leaflet. These findings were confirmed on cardiac magnetic resonance imaging (CMR). The differential diagnosis included athlete's heart, steroid-induced cardiomyopathy and non-obstructive hypertrophic cardiomyopathy. The patient was advised to discontinue both steroid use and intensive training. After 3 years of steroid abstinence but continued training, the syncopal episodes and the ECG abnormalities completely resolved, associated with regression of LVH on echocardiography and CMR.
Sen-Chowdhry S, Syrris P, Prasad SK, et al., 2008, Left-dominant arrhythmogenic cardiomyopathy: an under-recognized clinical entity., J AM COLL CARDIOL, Vol: 52, Pages: 2175-2187
Prasad SK, Clerk A, Cullingford TE, et al., 2008, Gene expression profiling of human hibernating myocardium: Increased expression of B-type natriuretic peptide and proenkephalin in hypocontractile <i>vs</i> normally-contracting regions of the heart, EUROPEAN JOURNAL OF HEART FAILURE, Vol: 10, Pages: 1177-1180, ISSN: 1388-9842
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- Citations: 5
Rajani R, Bhanot DK, Prasad SK, et al., 2008, Mitral valve myxoma: a case of mistaken identity, JOURNAL OF CARDIOVASCULAR MEDICINE, Vol: 9, Pages: 1290-1292, ISSN: 1558-2027
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- Citations: 3
Maceira AM, Prasad SK, Hawkins PN, et al., 2008, Cardiovascular Magnetic Resonance and prognosis in cardiac amyloidosis, JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE, Vol: 10, ISSN: 1097-6647
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- Citations: 187
Alpendurada F, Prasad SK, 2008, The missing spade: apical hypertrophic cardiomyopathy investigation, INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING, Vol: 24, Pages: 687-689, ISSN: 1569-5794
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- Citations: 2
Maceira Gonzalez AM, Cosin-Sales J, Prasad SK, et al., 2008, Myocardial trabeculation in healthy volunteers. Cardiovascular magnetic resonance study, EUROPEAN HEART JOURNAL, Vol: 29, Pages: 318-318, ISSN: 0195-668X
O' Hanlon R, Grasso A, Bucciarelli-Ducci C, et al., 2008, Correlation of wall thickness, scarring, and myocardial perfusion in hypertrophic cardiomyopathy, EUROPEAN HEART JOURNAL, Vol: 29, Pages: 58-58, ISSN: 0195-668X
O' Hanlon R, Grasso A, Bucciarelli-Ducci C, et al., 2008, Quantification of myocardial fibrosis in hypertrophic cardiomyopathy. Interstudy reproducibility, EUROPEAN HEART JOURNAL, Vol: 29, Pages: 55-55, ISSN: 0195-668X
Bucciarelli-Ducci C, Ng FS, Symmonds K, et al., 2008, The complex pathophysiology of acute myocardial infarction imaged by cardiovascular magnetic resonance - Infarction, edema, microvascular obstruction, and inducible ischemia, CIRCULATION, Vol: 118, Pages: E89-E92, ISSN: 0009-7322
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- Citations: 9
Locca D, Bucciarelli-Ducci C, Prasad SK, 2008, Syncope: Role of CMR in evaluating the aetiology in a patient with dual pathology, British Journal of Cardiology, Vol: 15, Pages: 215-216, ISSN: 0969-6113
We present a case in which the use of cardiovascular magnetic resonance (CMR) allowed the full pathology underlying syncope to be established. Copyright Medinews (Cardiology) Limited Reproduction Prohibited.
Wage R, Kafka H, Prasad S, 2008, Cardiac rhabdomyoma in an adult with a previous presumptive diagnosis of septal hypertrophy, CIRCULATION, Vol: 117, Pages: E469-E470, ISSN: 0009-7322
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- Citations: 5
O'Hanlon R, Prasad SK, Pennell DJ, 2008, Evaluation of nonischemic cardiomyopathies using cardiovascular magnetic resonance, JOURNAL OF NUCLEAR CARDIOLOGY, Vol: 15, Pages: 400-416, ISSN: 1071-3581
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- Citations: 5
Petretto E, Sarwar R, Grieve I, et al., 2008, Integrated genomic approaches implicate osteoglycin (<i>Ogn</i>) in the regulation of left ventricular mass, NATURE GENETICS, Vol: 40, Pages: 546-552, ISSN: 1061-4036
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- Citations: 134
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