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@article{Alatab:2020:10.1016/s2468-1253(19)30333-4,
author = {Alatab, S and Sepanlou, SG and Ikuta, K and Vahedi, H and Bisignano, C and Safiri, S and Sadeghi, A and Nixon, MR and Abdoli, A and Abolhassani, H and Alipour, V and Almadi, MAH and Almasi-Hashiani, A and Anushiravani, A and Arabloo, J and Atique, S and Awasthi, A and Badawi, A and Baig, AAA and Bhala, N and Bijani, A and Biondi, A and Borzì, AM and Burke, KE and Carvalho, F and Daryani, A and Dubey, M and Eftekhari, A and Fernandes, E and Fernandes, JC and Fischer, F and Haj-Mirzaian, A and Haj-Mirzaian, A and Hasanzadeh, A and Hashemian, M and Hay, SI and Hoang, CL and Househ, M and Ilesanmi, OS and Jafari, Balalami N and James, SL and Kengne, AP and Malekzadeh, MM and Merat, S and Meretoja, TJ and Mestrovic, T and Mirrakhimov, EM and Mirzaei, H and Mohammad, KA and Mokdad, AH and Monasta, L and Negoi, I and Nguyen, TH and Nguyen, CT and Pourshams, A and Poustchi, H and Rabiee, M and Rabiee, N and Ramezanzadeh, K and Rawaf, DL and Rawaf, S and Rezaei, N and Robinson, SR and Ronfani, },
doi = {10.1016/s2468-1253(19)30333-4},
journal = {The Lancet Gastroenterology & Hepatology},
pages = {17--30},
title = {The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017},
url = {http://dx.doi.org/10.1016/s2468-1253(19)30333-4},
volume = {5},
year = {2020}
}

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TY  - JOUR
AB  - BackgroundThe burden of inflammatory bowel disease (IBD) is rising globally, with substantial variation in levels and trends of disease in different countries and regions. Understanding these geographical differences is crucial for formulating effective strategies for preventing and treating IBD. We report the prevalence, mortality, and overall burden of IBD in 195 countries and territories between 1990 and 2017, based on data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017.MethodsWe modelled mortality due to IBD using a standard Cause of Death Ensemble model including data mainly from vital registrations. To estimate the non-fatal burden, we used data presented in primary studies, hospital discharges, and claims data, and used DisMod-MR 2.1, a Bayesian meta-regression tool, to ensure consistency between measures. Mortality, prevalence, years of life lost (YLLs) due to premature death, years lived with disability (YLDs), and disability-adjusted life-years (DALYs) were estimated. All of the estimates were reported as numbers and rates per 100000 population, with 95% uncertainty intervals (UI).FindingsIn 2017, there were 6·8 million (95% UI 6·4–7·3) cases of IBD globally. The age-standardised prevalence rate increased from 79·5 (75·9–83·5) per 100000 population in 1990 to 84·3 (79·2–89·9) per 100000 population in 2017. The age-standardised death rate decreased from 0·61 (0·55–0·69) per 100000 population in 1990 to 0·51 (0·42–0·54) per 100000 population in 2017. At the GBD regional level, the highest age-standardised prevalence rate in 2017 occurred in high-income North America (422·0 [398·7–446·1] per 100000) and the lowest age-standardised prevalence rates were observed in the Caribbean (6·7 [6·3–7·2] per 100000 population). High Socio-demogra
AU  - Alatab,S
AU  - Sepanlou,SG
AU  - Ikuta,K
AU  - Vahedi,H
AU  - Bisignano,C
AU  - Safiri,S
AU  - Sadeghi,A
AU  - Nixon,MR
AU  - Abdoli,A
AU  - Abolhassani,H
AU  - Alipour,V
AU  - Almadi,MAH
AU  - Almasi-Hashiani,A
AU  - Anushiravani,A
AU  - Arabloo,J
AU  - Atique,S
AU  - Awasthi,A
AU  - Badawi,A
AU  - Baig,AAA
AU  - Bhala,N
AU  - Bijani,A
AU  - Biondi,A
AU  - Borzì,AM
AU  - Burke,KE
AU  - Carvalho,F
AU  - Daryani,A
AU  - Dubey,M
AU  - Eftekhari,A
AU  - Fernandes,E
AU  - Fernandes,JC
AU  - Fischer,F
AU  - Haj-Mirzaian,A
AU  - Haj-Mirzaian,A
AU  - Hasanzadeh,A
AU  - Hashemian,M
AU  - Hay,SI
AU  - Hoang,CL
AU  - Househ,M
AU  - Ilesanmi,OS
AU  - Jafari,Balalami N
AU  - James,SL
AU  - Kengne,AP
AU  - Malekzadeh,MM
AU  - Merat,S
AU  - Meretoja,TJ
AU  - Mestrovic,T
AU  - Mirrakhimov,EM
AU  - Mirzaei,H
AU  - Mohammad,KA
AU  - Mokdad,AH
AU  - Monasta,L
AU  - Negoi,I
AU  - Nguyen,TH
AU  - Nguyen,CT
AU  - Pourshams,A
AU  - Poustchi,H
AU  - Rabiee,M
AU  - Rabiee,N
AU  - Ramezanzadeh,K
AU  - Rawaf,DL
AU  - Rawaf,S
AU  - Rezaei,N
AU  - Robinson,SR
AU  - Ronfani,L
AU  - Saxena,S
AU  - Sepehrimanesh,M
AU  - Shaikh,MA
AU  - Sharafi,Z
AU  - Sharif,M
AU  - Siabani,S
AU  - Sima,AR
AU  - Singh,JA
AU  - Soheili,A
AU  - Sotoudehmanesh,R
AU  - Suleria,HAR
AU  - Tesfay,BE
AU  - Tran,B
AU  - Tsoi,D
AU  - Vacante,M
AU  - Wondmieneh,AB
AU  - Zarghi,A
AU  - Zhang,Z-J
AU  - Dirac,M
AU  - Malekzadeh,R
AU  - Naghavi,M
DO  - 10.1016/s2468-1253(19)30333-4
EP  - 30
PY  - 2020///
SN  - 2468-1253
SP  - 17
TI  - The global, regional, and national burden of inflammatory bowel disease in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
T2  - The Lancet Gastroenterology & Hepatology
UR  - http://dx.doi.org/10.1016/s2468-1253(19)30333-4
UR  - https://www.sciencedirect.com/science/article/pii/S2468125319303334?via%3Dihub
UR  - http://hdl.handle.net/10044/1/74663
VL  - 5
ER  -

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