Imperial College London

Steven Riley

Faculty of MedicineSchool of Public Health

Professor of Infectious Disease Dynamics
 
 
 
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Contact

 

+44 (0)20 7594 2452s.riley

 
 
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Location

 

UG8Medical SchoolSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Kwok:2018:10.1186/s12879-018-3060-6,
author = {Kwok, KO and Read, JM and Tang, A and Chen, H and Riley, S and Kam, KM},
doi = {10.1186/s12879-018-3060-6},
journal = {BMC Infectious Diseases},
title = {A systematic review of transmission dynamic studies of methicillin-resistant Staphylococcus aureus in non-hospital residential facilities},
url = {http://dx.doi.org/10.1186/s12879-018-3060-6},
volume = {18},
year = {2018}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - BackgroundNon-hospital residential facilities are important reservoirs for MRSA transmission. However, conclusions and public health implications drawn from the many mathematical models depicting nosocomial MRSA transmission may not be applicable to these settings. Therefore, we reviewed the MRSA transmission dynamics studies in defined non-hospital residential facilities to: (1) provide an overview of basic epidemiology which has been addressed; (2) identify future research direction; and (3) improve future model implementation.MethodsA review was conducted by searching related keywords in PUBMED without time restriction as well as internet searches via Google search engine. We included only articles describing the epidemiological transmission pathways of MRSA/community-associated MRSA within and between defined non-hospital residential settings.ResultsAmong the 10 included articles, nursing homes (NHs) and correctional facilities (CFs) were two settings considered most frequently. Importation of colonized residents was a plausible reason for MRSA outbreaks in NHs, where MRSA was endemic without strict infection control interventions. The importance of NHs over hospitals in increasing nosocomial MRSA prevalence was highlighted. Suggested interventions in NHs included: appropriate staffing level, screening and decolonizing, and hand hygiene. On the other hand, the small population amongst inmates in CFs has no effect on MRSA community transmission. Included models ranged from system-level compartmental models to agent-based models. There was no consensus over the course of disease progression in these models, which were mainly featured with NH residents /CF inmates/ hospital patients as transmission pathways. Some parameters used by these models were outdated or unfit.ConclusionsImportance of NHs has been highlighted from these current studies addressing scattered aspects of MRSA epidemiology. However, the wide variety of non-hospital residential settings suggest th
AU - Kwok,KO
AU - Read,JM
AU - Tang,A
AU - Chen,H
AU - Riley,S
AU - Kam,KM
DO - 10.1186/s12879-018-3060-6
PY - 2018///
SN - 1471-2334
TI - A systematic review of transmission dynamic studies of methicillin-resistant Staphylococcus aureus in non-hospital residential facilities
T2 - BMC Infectious Diseases
UR - http://dx.doi.org/10.1186/s12879-018-3060-6
UR - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000431054200003&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR - http://hdl.handle.net/10044/1/60343
VL - 18
ER -