Imperial College London


Faculty of MedicineNational Heart & Lung Institute

Professor of Paediatric Respiratory Medicine



+44 (0)20 7594 3167s.saglani




368Sir Alexander Fleming BuildingSouth Kensington Campus





Sejal Saglani completed her undergraduate degree in medicine at the University of Leicester. Dr Saglani then undertook her clinical training in general paediatrics in the Thames Region. Further training at The Royal London Hospital, Great Ormond Street Hospital and The Royal Brompton Hospital allowed her to obtain her Certificate of Specialist Training in Respiratory Paediatrics.

Dr Saglani took time out of her clinical training to carry out her postgraduate research at the National Heart and Lung Institute and The Royal Brompton Hospital, funded by Asthma UK, and supervised by Professor Andrew Bush and Professor Peter Jeffery.  She obtained her MD degree investigating the pathology of infant and preschool wheeze and received the NHLI Thesis prize for best thesis. Her main clinical interests include the diagnosis and management of difficult asthma in children and also the management of severe infant and preschool wheeze.

Subsequent to completing her clinical training, Dr Saglani obtained a British Lung Foundation Research Fellowship to develop a neonatal mouse model of allergic airways disease. The establishment of this model has allowed her to obtain a Wellcome Intermediate Clinical Fellowship.

Dr Saglani's research interests include the pathology of infant and preschool wheeze, mechanisms of onset of airway remodelling in severe preschool wheeze and disease modifying therapies for preschool wheeze and childhood difficult asthma.



Edwards MR, Saglani S, Schwarze J, et al., Addressing Unmet Needs in Understanding Asthma Mechanisms, European Respiratory Journal, ISSN:1399-3003

Del Giacco SR, Bakirtas A, Bel E, et al., 2017, Allergy in severe asthma, Allergy, Vol:72, ISSN:0105-4538, Pages:207-220

Andersson CK, Adams A, Nagakumar P, et al., 2016, Intraepithelial neutrophils in pediatric severe asthma are associated with better lung function., J Allergy Clin Immunol

Bossley CJ, Fleming L, Ullmann N, et al., 2016, Assessment of corticosteroid response in pediatric patients with severe asthma by using a multidomain approach, Journal of Allergy and Clinical Immunology, Vol:138, ISSN:0091-6749, Pages:413-+

Cook J, Saglani S, 2016, Pathogenesis and prevention strategies of severe asthma exacerbations in children, Current Opinion in Pulmonary Medicine, Vol:22, ISSN:1070-5287, Pages:25-31

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