Imperial College London

ProfessorSimonSchultz

Faculty of EngineeringDepartment of Bioengineering

Professor of Neurotechnology
 
 
 
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Contact

 

+44 (0)20 7594 1533s.schultz Website

 
 
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Location

 

4.11Royal School of MinesSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Berditchevskaia:2016:10.1038/srep27389,
author = {Berditchevskaia, A and Caze, R and Schultz, SR},
doi = {10.1038/srep27389},
journal = {Scientific Reports},
title = {Performance in a GO/NOGO perceptual task reflects a balance between impulsive and instrumental components of behaviour},
url = {http://dx.doi.org/10.1038/srep27389},
volume = {6},
year = {2016}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - In recent years, simple GO/NOGO behavioural tasks have become popular due to the relative ease with which they can be combined with technologies such as in vivo multiphoton imaging. To date, it has been assumed that behavioural performance can be captured by the average performance across a session, however this neglects the effect of motivation on behaviour within individual sessions. We investigated the effect of motivation on mice performing a GO/NOGO visual discrimination task. Performance within a session tended to follow a stereotypical trajectory on a Receiver Operating Characteristic (ROC) chart, beginning with an over-motivated state with many false positives, and transitioning through a more or less optimal regime to end with a low hit rate after satiation. Our observations are reproduced by a new model, the Motivated Actor-Critic, introduced here. Our results suggest that standard measures of discriminability, obtained by averaging across a session, may significantly underestimate behavioural performance.
AU - Berditchevskaia,A
AU - Caze,R
AU - Schultz,SR
DO - 10.1038/srep27389
PY - 2016///
SN - 2045-2322
TI - Performance in a GO/NOGO perceptual task reflects a balance between impulsive and instrumental components of behaviour
T2 - Scientific Reports
UR - http://dx.doi.org/10.1038/srep27389
UR - http://hdl.handle.net/10044/1/32707
VL - 6
ER -