Imperial College London
Portrait Picture

ProfessorShiraneeSriskandan

Faculty of Medicine, Department of Infectious Disease

Professor of Infectious Diseases
 
 
 
//

Contact

 

s.sriskandan

 
 
//

Assistant

 

Ms Teyanna Gaeta +44 (0)20 3313 1943

 
//

Location

 

8N21ACWBCommonwealth BuildingHammersmith Campus

//

Summary

 

Publications

Publication Type
Year
to

216 results found

Belcher E, Evans TW, Sriskandan S, Mitchell JAet al., 2003, Escherichia coli induces nitric oxide release in cardiovascular tissue via a toll like receptor 4-independent pathway, Meeting of the British-Pharmacological-Society-Clinical-Pharmacology-Section, Publisher: WILEY, Pages: U16-U16, ISSN: 0007-1188

Conference paper

Belcher E, Evans TW, Sriskandan S, Mitchell JAet al., 2003, Gram-positive <i>Staphylococcus aureus</i> contrasts with Gram-negative <i>Escherichia coli</i> in the induction of tumour necrosis factor-alpha and nitric oxide from macrophages in urine, Meeting of the Intensive-Care-Society, Publisher: OXFORD UNIV PRESS, Pages: 540P-541P, ISSN: 0007-0912

Conference paper

Desai PR, Sriskandan S, 2003, Hypothermia in a child secondary to ibuprofen [2], Archives of Disease in Childhood, Vol: 88, Pages: 87-88, ISSN: 0003-9888

  • Cite
  • Citations: 11
Journal article

Fenwick P, Ryan C, Sriskandan S, Cohen Jet al., 2003, Application of a rat model of streptococcal shock to evaluate on-line hemoperfusion and removal of circulating superantigens, CRITICAL CARE MEDICINE, Vol: 31, Pages: 171-178, ISSN: 0090-3493

Journal article

Hopkins P, Sriskandan S, 2002, Gram-positive bacterial infection in severe sepsis, Clinical Intensive Care, Vol: 13, Pages: 147-160, ISSN: 0956-3075

Journal article

Belcher E, Evans TW, Sriskandan S, Mitchell JAet al., 2002, The main site of iNOS activity induced by Gram postive <i>Staphylococcus aureus</i> may be blood vessels and not macrophages:: Comparisons with Gram negative <i>Escherichia coli</i>, Winter Meeting of the British-Thoracic-Society, Publisher: BRITISH MED JOURNAL PUBL GROUP, ISSN: 0040-6376

Conference paper

Unnikrishnan M, Altmann DM, Proft T, Wahid F, Cohen J, Fraser JD, Sriskandan Set al., 2002, The bacterial superantigen streptococcal mitogenic exotoxin Z is the major immunoactive agent of <i>Streptococcus pyogenes</i>, JOURNAL OF IMMUNOLOGY, Vol: 169, Pages: 2561-2569, ISSN: 0022-1767

Journal article

Ferguson M, Edwards R, Finney SJ, Taylor G, Sriskandan Set al., 2002, Proteolytic cleavage of human interleukin-8 by invasive Group A Streptococcal strains abrogates chemokine activity and recruitment of immune response, 42nd Interscience Conference on Antimicrobial Agents and Chemotherapy

Conference paper

Unnikrishnan M, Cohen J, Sriskandan S, 2001, Complementation of a <i>speA</i> negative <i>Streptococcus pyogenes</i> with <i>speA</i> -: effects on virulence and production of streptococcal pyrogenic exotoxin A, MICROBIAL PATHOGENESIS, Vol: 31, Pages: 109-114, ISSN: 0882-4010

Journal article

Sriskandan S, Unnikrishnan M, Krausz T, Dewchand H, Van Noorden S, Cohen J, Altmann DMet al., 2001, Enhanced susceptibility to superantigen-associated streptococcal sepsis in human leukocyte antigen-DQ transgenic mice, JOURNAL OF INFECTIOUS DISEASES, Vol: 184, Pages: 166-173, ISSN: 0022-1899

Journal article

Sriskandan S, Kemball-Cook G, Moyes D, Canvin J, Tuddenham E, Cohen Jet al., 2000, Contact activation in shock caused by invasive group A <i>Streptococcus pyogenes</i>, CRITICAL CARE MEDICINE, Vol: 28, Pages: 3684-3691, ISSN: 0090-3493

Journal article

Sriskandan S, Unnikrishnan M, Krausz T, Cohen Jet al., 2000, Mitogenic factor (MF) is the major DNase of serotype M89 <i>Streptococcus pyogenes</i>, MICROBIOLOGY-SGM, Vol: 146, Pages: 2785-2792, ISSN: 1350-0872

Journal article

Sriskandan S, Cohen J, 2000, Kallikrein-kinin system activation in streptococcal toxic shock syndrome, CLINICAL INFECTIOUS DISEASES, Vol: 30, Pages: 961-962, ISSN: 1058-4838

Journal article

Sriskandan S, 2000, Assay for superantigens., Methods Mol Med, Vol: 36, Pages: 67-79, ISSN: 1543-1894

This chapter describes a quantitative assay for the streptococcal superantigen, streptococcal pyrogenic exotoxin A (SPEA), which can be used in broth, tissue-culture media, and certain sera. The protocol can be adapted to allow measurement of any bacterial superantigen or protein toxin, using different oligonucleotides to amplify the coding sequences from bacterial DNA. Previously, measurement of bacterial toxins such as SPEA was limited by poor test sensitivity and test samples could only be analyzed if concentrated. Techniques included Ouchterlony immunodiffusion or enzyme-linked immuno-sorbent assay (ELISA), although the lower limit of detection was 100-fold greater than that achievable in this system. (1-3) Recent methods described have achieved improved sensitivities, some using sandwich ELISA techniques, others using competitive ELISA techniques. (4-8).

Journal article

Unnikrishnan M, Cohen J, Sriskandan S, 1999, Growth-phase-dependent expression of virulence factors in an M1T1 clinical isolate of <i>Streptococcus pyogenes</i>, INFECTION AND IMMUNITY, Vol: 67, Pages: 5495-5499, ISSN: 0019-9567

Journal article

Sriskandan S, Unnikrishnan M, Krausz T, Cohen Jet al., 1999, Molecular analysis of the role of streptococcal pyrogenic exotoxin A (SPEA) in invasive soft-tissue infection resulting from <i>Streptococcus pyogenes</i>, MOLECULAR MICROBIOLOGY, Vol: 33, Pages: 778-790, ISSN: 0950-382X

Journal article

Sriskandan S, Cohen J, 1999, Gram-positive sepsis - Mechanisms and differences from gram-negative sepsis, INFECTIOUS DISEASE CLINICS OF NORTH AMERICA, Vol: 13, Pages: 397-+, ISSN: 0891-5520

Journal article

Sriskandan S, Kemball-Cook G, Moyes D, Canvin J, Tuddenham E, Cohen Jet al., 1999, Coagulation abnormalities in severe streptococcal shock syndrome, SHOCK, Vol: 12, Pages: 21-22, ISSN: 1073-2322

Journal article

Sriskandan S, Moves D, Cohen J, 1998, Previous exposure to superantigen enhances host inflammatory responses and susceptibility to infection with SPEA-producing Streptococcus pyogenes, International Congress and Symposium Series - Royal Society of Medicine, ISSN: 0142-2367

Journal article

Sriskandan S, McKee A, Hall L, Cohen Jet al., 1997, Comparative effects of clindamycin and ampicillin on superantigenic activity of Streptococcus pyogenes, JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, Vol: 40, Pages: 275-277, ISSN: 0305-7453

Journal article

Curtis N, Jacobs M, Sriskandan S, 1997, Musculoskeletal side-effects of varicella, LANCET, Vol: 349, Pages: 1623-1624, ISSN: 0140-6736

Journal article

Sriskandan S, Moyes D, Buttery LK, Wilkinson J, Evans TJ, Polak J, Cohen Jet al., 1997, The role of nitric oxide in experimental murine sepsis due to pyrogenic exotoxin A-producing Streptococcus pyogenes, INFECTION AND IMMUNITY, Vol: 65, Pages: 1767-1772, ISSN: 0019-9567

Journal article

Jones HA, Sriskandan S, Peters AM, Pride NB, Krausz T, Boobis AR, Haslett Cet al., 1997, Dissociation of neutrophil emigration and metabolic activity in lobar pneumonia and bronchiectasis, EUROPEAN RESPIRATORY JOURNAL, Vol: 10, Pages: 795-803, ISSN: 0903-1936

Journal article

Feng Q, Rahman SU, Rhodes CG, Hayes MJ, Sriskandan S, Ind PW, Jones T, Hughes JMBet al., 1997, Pulmonary and cardiac beta-adrenoceptor density in vivo in asthmatic subjects, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 155, Pages: 1130-1134, ISSN: 1073-449X

Journal article

Sriskandan S, Moyes D, Lemm G, Cohen Jet al., 1996, Lymphotoxin-alpha (TNF-beta) during sepsis, CYTOKINE, Vol: 8, Pages: 933-937, ISSN: 1043-4666

Journal article

Sriskandan S, Moyes D, Cohen J, 1996, Detection of circulating bacterial superantigen and lymphotoxin-alpha in patients with streptococcal toxic-shock syndrome, LANCET, Vol: 348, Pages: 1315-1316, ISSN: 0140-6736

Journal article

Hayes MJ, Qing F, Rhodes CG, Rahman SU, Ind PW, Sriskandan S, Jones T, Hughes JMBet al., 1996, In vivo quantification of human pulmonary beta-adrenoceptors: Effect of beta-agonist therapy, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 154, Pages: 1277-1283, ISSN: 1073-449X

Journal article

Sriskandan S, Moyes D, Buttery LK, Krausz T, Evans TJ, Polak J, Cohen Jet al., 1996, Streptococcal pyrogenic exotoxin a release, distribution, and role in a murine model of fasciitis and multiorgan failure due to Streptococcus pyogenes, JOURNAL OF INFECTIOUS DISEASES, Vol: 173, Pages: 1399-1407, ISSN: 0022-1899

Journal article

Sriskandan S, Evans TJ, Cohen J, 1996, Bacterial superantigen-induced human lymphocyte responses are nitric oxide dependent and mediated by IL-12 and IFN-gamma, JOURNAL OF IMMUNOLOGY, Vol: 156, Pages: 2430-2435, ISSN: 0022-1767

Journal article

Sriskandan S, Labrecque LG, Schofield J, 1996, Diffuse pneumonia associated with infectious mononucleosis: Detection of Epstein-Barr virus in lung tissue by in situ hybridization, CLINICAL INFECTIOUS DISEASES, Vol: 22, Pages: 578-579, ISSN: 1058-4838

Journal article

This data is extracted from the Web of Science and reproduced under a licence from Thomson Reuters. You may not copy or re-distribute this data in whole or in part without the written consent of the Science business of Thomson Reuters.

Request URL: http://wlsprd.imperial.ac.uk:80/respub/WEB-INF/jsp/search-html.jsp Request URI: /respub/WEB-INF/jsp/search-html.jsp Query String: id=00167628&limit=30&person=true&page=7&respub-action=search.html