Imperial College London
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ProfessorShiraneeSriskandan

Faculty of Medicine, Department of Infectious Disease

Professor of Infectious Diseases
 
 
 
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Contact

 

s.sriskandan

 
 
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Assistant

 

Ms Teyanna Gaeta +44 (0)20 3313 1943

 
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Location

 

8N21ACWBCommonwealth BuildingHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Pearson:2017:10.1016/j.jinf.2017.03.001,
author = {Pearson, M and Fallowfield, JL and Davey, T and Thorpe, N and Allsopp, A and Shaw, A and Wilson, D and Sriskandan, S and Lamb, L},
doi = {10.1016/j.jinf.2017.03.001},
journal = {Journal of Infection},
pages = {585--589},
title = {Asymptomatic group A Streptococcal throat carriage in Royal Marines recruits and young officers},
url = {http://dx.doi.org/10.1016/j.jinf.2017.03.001},
volume = {74},
year = {2017}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Aims A prospective observational study was conducted in Royal Marines (RM) recruits to investigate throat carriage of group A Streptococcus (GAS) and incidence of soft tissue infections. Methods 1012 RM recruits were followed through a 32-week training programme, with throat swabs being obtained in weeks 1, 6, 15, and 32. Alongside a separate cohort of 46 RM Young Officers (YO) undergoing training were sampled in parallel. Results Carriage of group A Streptococcus was detected in only 5/1012 (0.49%) recruits at the beginning of training and remained low throughout training. There was no association between GAS carriage and development of soft tissue infection. There was no carriage of GAS in the smaller YO cohort at the start of training, (0/46). At week 6, a surge in GAS carriage was detected in 8/46 (17%) YO, that could be ascribed to a cluster of GAS genotype emm83. Conclusions Asymptomatic GAS carriage is very infrequent among young adults in England and this should be borne in mind when considering the relevance of a positive throat swab result in symptomatic patients or outbreaks. Despite low prevalence, there is however potential for GAS to rapidly and transiently disseminate among adults during outbreaks.
AU  - Pearson,M
AU  - Fallowfield,JL
AU  - Davey,T
AU  - Thorpe,N
AU  - Allsopp,A
AU  - Shaw,A
AU  - Wilson,D
AU  - Sriskandan,S
AU  - Lamb,L
DO  - 10.1016/j.jinf.2017.03.001
EP  - 589
PY  - 2017///
SN  - 1532-2742
SP  - 585
TI  - Asymptomatic group A Streptococcal throat carriage in Royal Marines recruits and young officers
T2  - Journal of Infection
UR  - http://dx.doi.org/10.1016/j.jinf.2017.03.001
UR  - http://hdl.handle.net/10044/1/45480
VL  - 74
ER  -
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