Summary
Dr. Sara Bonvini is Research Associate in the Respiratory Pharmacology group within the National Heart and Lung Institute.
Sara completed her PhD in 2016 where she is investigated the role of the ion channel TRPV4 in airway sensory nerves. Activation of airway sensory nerves in the lungs can cause reflex events such as cough and bronchoconstriction, both of which are characteristic symptoms of respiratory disease. New and effective therapies to combat these debilitating symptoms are urgently needed.
Her current research involves investigating mechanisms of enhanced reflex responses in airway disease with the aim of developing novel therapies
During her time within the Respiratory Pharmacology laboratory, Sara has been a recipient of a number of prizes including NHLI Day best poster presentation (2013) and best oral presentation (2014), the BALR Young Scientist prize at the summer meeting of 2014, the GSK prize for best oral presentation at the BPS Pharmacology meeting 2014, the best abstract by a Young Investigator in Assembly 5 at the ERS congress 2015 and the Stuart J. Hirst award in 2018.
Publications
Journals
Di Poto C, Tian X, Mellors S, et al., 2024, A microfluidic chip-based capillary zone electrophoresis-mass spectrometry method for measuring adenosine 5'-Triphosphate and its similar nucleotide analogues., Anal Chim Acta, Vol:1298
Bonvini SJ, 2020, Cause or Effect? Stretching to Understand the Inflammatory Role of Elastin Fiber Breakdown in Chronic Obstructive Pulmonary Disease, American Journal of Respiratory Cell and Molecular Biology, Vol:63, ISSN:1044-1549, Pages:558-559
Bonvini SJ, Birrell MA, Dubuis E, et al., 2020, Novel airway smooth muscle-mast cell interactions and a role for the TRPV4-ATP axis in non-atopic asthma, European Respiratory Journal, Vol:56, ISSN:0903-1936
Lahousse L, Bahmer T, Cuevas-Ocaña S, et al., 2020, ERS International Congress, Madrid, 2019: highlights from the Airway Diseases, Asthma and COPD Assembly, Erj Open Research, Vol:6, ISSN:2312-0541
Smith JA, Wortley MA, Bonvini S, et al., 2020, "Truth is ever to be found in simplicity, and not in the multiplicity and confusion of things" - Sir Isaac Newton, European Respiratory Journal, Vol:55, ISSN:0903-1936