Publications
251 results found
Elfaki N, Lutaaya N, Hardiman PJ, et al., 2021, Oocyte cryopreservation for social reasons versus fertility preservation; a systematic review, Publisher: WILEY, Pages: 238-238, ISSN: 1470-0328
Sorbi F, Capezzuoli T, Saso S, et al., 2021, The relation between endometrioma and ovarian cancer, MINERVA OBSTETRICS AND GYNECOLOGY, Vol: 73, Pages: 347-353, ISSN: 2724-606X
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- Citations: 1
Hughes T, Bracewell-Milnes T, Saso S, et al., 2021, A review on the motivations, decision-making factors, attitudes and experiences of couples using pre-implantation genetic testing for inherited conditions, HUMAN REPRODUCTION UPDATE, Vol: 27, Pages: 944-966, ISSN: 1355-4786
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- Citations: 11
Ahmed-Salim Y, Galazis N, Bracewell-Milnes T, et al., 2021, The application of metabolomics in ovarian cancer management: a systematic review, INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, Vol: 31, Pages: 754-774, ISSN: 1048-891X
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- Citations: 7
Kasaven LS, Jones BP, Keays R, et al., 2021, Anaesthetic considerations for fertility-sparing surgery and uterine transplantation, ANAESTHESIA, Vol: 76, Pages: 46-55, ISSN: 0003-2409
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- Citations: 2
Jones BP, Ranaei-Zamani N, Vali S, et al., 2021, Options for acquiring motherhood in absolute uterine factor infertility; adoption, surrogacy and uterine transplantation, OBSTETRICIAN & GYNAECOLOGIST, Vol: 23, Pages: 138-147, ISSN: 1467-2561
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- Citations: 9
Barcroft JF, Galazis N, Jones BP, et al., 2021, Fertility treatment and cancers-the eternal conundrum: a systematic review and meta-analysis., Human Reproduction, Vol: 36, Pages: 1093-1107, ISSN: 0268-1161
STUDY QUESTION: Does fertility treatment (FT) significantly increase the incidence of breast, ovarian, endometrial or cervical cancer? SUMMARY ANSWER: Overall, FT does not significantly increase the incidence of breast, ovarian or endometrial cancer and may even reduce the incidence of cervical cancer. WHAT IS KNOWN ALREADY: Infertility affects more than 14% of couples. Infertility and nulliparity are established risk factors for endometrial, ovarian and breast cancer, yet the association with FT is more contentious. STUDY DESIGN, SIZE, DURATION: A literature search was carried out using Cochrane Library, EMBASE, Medline and Google Scholar up to December 2019. Peer-reviewed studies stating cancer incidence (breast, ovarian, endometrial or cervical) in FT and no-FT groups were identified. Out of 128 studies identified, 29 retrospective studies fulfilled the criteria and were included (n = 21 070 337). PARTICIPANTS/MATERIALS, SETTING, METHODS: In the final meta-analysis, 29 studies were included: breast (n = 19), ovarian (n = 19), endometrial (n = 15) and cervical (n = 13), 17 studies involved multiple cancer types and so were included in each individual cancer meta-analysis. Primary outcome of interest was cancer incidence (breast, ovarian, endometrial and cervical) in FT and no-FT groups. Secondary outcome was cancer incidence according to specific fertility drug exposure. Odds ratio (OR) and random effects model were used to demonstrate treatment effect and calculate pooled treatment effect, respectively. A meta-regression and eight sub-group analyses were performed to assess the impact of the following variables, maternal age, infertility, study size, outliers and specific FT sub-types, on cancer incidence. MAIN RESULTS AND THE ROLE OF CHANCE: Cervical cancer incidence was significantly lower in the FT group compared with the no-FT group: OR 0.68 (95% CI 0.46-0.99). The incidences
Sorbi F, Fambrini M, Saso S, et al., 2021, Office hysteroscopy in pre- and post-menopausal women: a predictive model, GYNECOLOGICAL ENDOCRINOLOGY, Vol: 37, Pages: 206-210, ISSN: 0951-3590
Jones BP, Rajamanoharan A, Williams NJ, et al., 2021, Uterine Transplantation Using Living Donation: A Cross-sectional Study Assessing Perceptions, Acceptability, and Suitability, TRANSPLANTATION DIRECT, Vol: 7, ISSN: 2373-8731
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- Citations: 5
Patel S, John S, Pactat G, et al., 2021, PERIOPERATIVE ANAEMIA AND ITS PERILS, Publisher: BMJ PUBLISHING GROUP, Pages: A182-A182, ISSN: 1048-891X
Grewal K, Jones B, L'Heveder A, et al., 2021, The use of intra-operative ultrasound in gynecological surgery: a review, Future Science OA, Vol: 7, ISSN: 2056-5623
Ultrasound is a readily available, safe and portable imaging modality that is widely applied in gynecology. However, there is limited guidance for its use intra-operatively especially with complex gynecological procedures. This narrative review examines the existing literature published on the use of intraoperative ultrasound (IOUS) in benign gynecology and in gynecological oncology. We searched for the following terms: ‘intraoperative,’ ‘ultrasonography,’ ‘gynecology’ and ‘oncology’ using Pubmed/Medline. IOUS can minimize complications and facilitate difficult benign gynecological procedures. There is also a role for its use in gynecological oncology surgery and fertility-sparing surgery. The use of IOUS in gynecological surgery is an emerging field which improves visualization in the surgical field and aids completion of minimally invasive techniques.
Platts S, Trigg B, Bracewell-Milnes T, et al., 2021, Exploring women's attitudes, knowledge, and intentions to use oocyte freezing for non-medical reasons: A systematic review, ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, Vol: 100, Pages: 383-393, ISSN: 0001-6349
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- Citations: 15
Kasaven LS, Saso S, Barcroft J, et al., 2021, Authors' reply Re: Implications for the future of Obstetrics and Gynaecology following the COVID-19 pandemic: a commentary, BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Vol: 128, Pages: 616-617, ISSN: 1470-0328
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- Citations: 1
Jones BP, Rajamanoharan A, Vali S, et al., 2021, Perceptions and Motivations for Uterus Transplant in Transgender Women, JAMA NETWORK OPEN, Vol: 4, ISSN: 2574-3805
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- Citations: 16
Glasbey JC, Omar O, Nepogodiev D, et al., 2021, Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pandemic, BRITISH JOURNAL OF SURGERY, Vol: 108, Pages: 88-96, ISSN: 0007-1323
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- Citations: 43
Bracewell-Milnes T, Saso S, Jones B, et al., 2021, A systematic review exploring the patient decision-making factors and attitudes towards pre-implantation genetic testing for aneuploidy and gender selection, ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, Vol: 100, Pages: 17-29, ISSN: 0001-6349
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- Citations: 10
Murugesu S, Galazis N, Jones B, et al., 2020, Evaluating the use of Telemedicine in Gynaecological Practice: A Systematic Review, BMJ Open, Vol: 10, ISSN: 2044-6055
Objectives The aim of this systematic review is to examine the use of telemedicine in the delivery and teaching of gynaecological clinical practice. To our knowledge, no other systematic review has assessed this broad topic.Design Systematic review of all studies investigating the use of telemedicine in the provision of gynaecological care and education. The search for eligible studies followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and focused on three online databases: PubMed, Science Direct and SciFinder.Eligibility criteria Only studies within gynaecology were considered for this review. Studies covering only obstetrics and with minimal information on gynaecology, or clinical medicine in general were excluded. All English language, peer-reviewed human studies were included. Relevant studies published up to the date of final submission of this review were considered with no restrictions to the publication year.Data extractions and synthesis Data extracted included author details, year of publication and country of the study, study aim, sample size, methodology, sample characteristics, outcome measures and a summary of findings. Data extraction and qualitative assessment were performed by the first author and crossed checked by the second author. Quality assessment for each study was assessed using the Newcastle-Ottawa scale.Results A literature search carried out in August 2020 yielded 313 records published between 1992 and 2018. Following a rigorous selection process, only 39 studies were included for this review published between 2000 and 2018. Of these, 19 assessed gynaecological clinical practice, eight assessed gynaecological education, one both, and 11 investigated the feasibility of telemedicine within gynaecological practice. 19 studies were classified as good, 12 fair and eight poor using the Newcastle-Ottawa scale. Telecolposcopy and abortion care were two areas where telemedicine was found to be effective in p
Phelps DL, Saso S, Ghaem-Maghami S, 2020, Is ovarian cancer surgery stuck in the dark ages?: a commentary piece reviewing surgical technologies, BRITISH JOURNAL OF CANCER, Vol: 123, Pages: 1471-1473, ISSN: 0007-0920
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- Citations: 2
Kasaven LS, Saso S, Barcroft J, et al., 2020, Implications for the future of obstetrics and gynaecology following the COVID-19 pandemic: a commentary., BJOG: an International Journal of Obstetrics and Gynaecology, Vol: 127, Pages: 1318-1323, ISSN: 1470-0328
In March 2020, the World Health Organization (WHO) declared COVID-19 a global pandemic. At the time of writing, more than 261,184 cases of COVID-19 have been confirmed in the UK resulting in over 36,914 directly attributable deaths.1 The National Health Service (NHS) has been confronted with the unprecedented task of dealing with the enormity of the resultant morbidity and mortality. In addition, the workforce has been depleted as a direct consequence of the disease, in most cases temporarily, but in some tragic cases permanently.
Phelps DL, Saso S, Ghaem-Maghami S, 2020, Analysis of worldwide surgical outcomes in COVID-19-infected patients: a gynecological oncology perspective, Future Science OA, Vol: 6, Pages: 1-8, ISSN: 2056-5623
Coronavirus Disease 2019 (COVID-19) guidance limits all but the most urgent surgery in the United Kingdom. We review the literature and our experience in gynecology to assess perioperative outcomes. PubMed was searched with (surg*[Title])AND(COVID[Title]), (surg*[Title])AND(2019-nCoV[Title]), and (surg*[Title])AND(SARS-CoV-2[Title]), and 67 COVID-19-positive surgical patients across ten hospitals in four countries are included. Median mortality was 33%. Cardiac and pulmonary co-morbidities associated with higher risk of COVID-19-positive postoperative death. Mortality was high in neurosurgery (80%) and the lowest in gynecological oncology surgery (none). This analysis provides an evidence base on which to consider surgical risk assessment for different specialties. Risk of perioperative death needs to be assessed in the context of patients’ co-morbidities and surgical specialty. An individualized approach toward surgical decision making is imperative.
Jones BP, Saso S, Quiroga I, et al., 2020, Limited Availability of Deceased Uterus Donors: A UK Perspective, TRANSPLANTATION, Vol: 104, Pages: E250-E251, ISSN: 0041-1337
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- Citations: 7
Galazis N, Mappouridou S, Saso S, et al., 2020, Applying the vaginal approach to ovarian cystectomy: current evidence and future applications, FUTURE SCIENCE OA, Vol: 6, ISSN: 2056-5623
Bayar E, Saso S, Galazis N, et al., 2020, Impact of polyunsaturated fatty acid supplementation on assisted reproductive technology (ART) outcomes: a systematic review, 36th Virtual Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology (ESHRE), Publisher: OXFORD UNIV PRESS, Pages: 1424-1424, ISSN: 0268-1161
Jones BP, L'Heveder A, Saso S, et al., 2020, Re: Sports gynaecology Reply, OBSTETRICIAN & GYNAECOLOGIST, Vol: 22, Pages: 245-246, ISSN: 1467-2561
Galazis N, Mappouridou S, Saso S, et al., 2020, Applying the vaginal approach for benign ovarian cystectomy: current evidence and future applications, FUTURE SCIENCE OA, Vol: 6, ISSN: 2056-5623
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- Citations: 5
Jones BP, Vali S, Saso S, et al., 2020, Endometrial autotransplantation in rabbits: Potential for fertility restoration in severe Asherman's syndrome, EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, Vol: 248, Pages: 14-23, ISSN: 0301-2115
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- Citations: 1
Al-Memar M, Vaulet T, Fourie H, et al., 2020, Intrauterine haematomas in the first trimester and pregnancy complications, Ultrasound in Obstetrics and Gynecology, Vol: 55, Pages: 536-545, ISSN: 0960-7692
OBJECTIVES: The role of intrauterine haematoma on pregnancy outcomes remains uncertain. Some studies report an association with miscarriage, whilst others refute this. The impact on long-term outcomes is not known. We aimed to assess if intrauterine haematomas detected using ultrasonography in the first trimester are associated with adverse pregnancy outcomes. METHODS: A prospective observational cohort study at Queen Charlotte's & Chelsea Hospital, London, was conducted between March 2014 and March 2016. Participants with intrauterine pregnancies were recruited and underwent serial ultrasound scans in the first trimester. Clinical symptoms, including pelvic pain and vaginal bleeding were recorded using validated symptom scores at each visit. The presence, location and size of any intrauterine haematoma seen on ultrasonography was noted. Pregnancy outcomes were obtained from hospital records. RESULTS: Of 1003 recruited participants, 268 had an intrauterine haematoma (27%). The presence of intrauterine haematoma in the first trimester was associated with preterm birth (OR 1.94; 95% CI 1.07-3.53). No association was found with miscarriage (OR 0.916; 95% CI 0.571-1.471). This was irrespective of the absolute size of the haematoma or the presence or absence of vaginal bleeding and pelvic pain. A retroplacental haematoma was associated with an increase in overall antenatal complications (P = 0.0395). CONCLUSIONS: Our data demonstrates no association between the presence of intrauterine haematoma in the first trimester and first trimester miscarriage. However, a relationship with preterm birth independent of the presence of symptoms of pain and bleeding is evident. These women should be counseled about their increased risk of preterm birth and possibly be offered increased surveillance during their pregnancies. This article is protected by copyright. All rights reserved.
Galazis N, Saso S, Sorbi F, et al., 2020, Intraoperative Ultrasound during Fertility-Sparing Surgery: A Systematic Review and Practical Applications, GYNECOLOGIC AND OBSTETRIC INVESTIGATION, Vol: 85, Pages: 127-148, ISSN: 0378-7346
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- Citations: 6
Jones BP, Kasaven L, L'Heveder A, et al., 2020, Perceptions, outcomes, and regret following social egg freezing in the UK; a cross-sectional survey, ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, Vol: 99, Pages: 324-332, ISSN: 0001-6349
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- Citations: 35
Lathouras K, Saso S, Jones BP, et al., 2020, Transvaginal laparoscopic salpingo-oophorectomy: an oncological risk-reducing procedure, FUTURE SCIENCE OA, Vol: 6, ISSN: 2056-5623
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