ProfessorStuartCook

Faculty of Medicine, Institute of Clinical Sciences

Visiting Professor

Contact

+44 (0)20 3313 1346stuart.cook

Location

RF 16Sydney StreetRoyal Brompton Campus

Summary

Professor Stuart Cook is the head of the Cardiovascular Genetics and Genomics group within Genetics & Imaging at the National Heart and Lung Institute (NHLI).

Publications

Journals

Adami E, Viswanathan S, Widjaja AA, et al.Adami E, Viswanathan S, Widjaja AA, Ng B, Chothani S, Zhihao N, Tan J, Lio PM, George BL, Altunoglu U, Ghosh K, Paleja BS, Schafer S, Reversade B, Albani S, Ling ALH, O'Reilly S, Cook SA close, 2021, IL11 is elevated in systemic sclerosis and IL11-dependent ERK signaling underlies TGFβ-mediated activation of dermal fibroblasts., Rheumatology (oxford)

Whiffin N, Karczewski KJ, Zhang X, et al.Whiffin N, Karczewski KJ, Zhang X, Chothani S, Smith MJ, Evans DG, Roberts AM, Quaife NM, Schafer S, Rackham O, Alfoeldi J, O'Donnell-Luria AH, Francioli LC, Armean IM, Aguilar Salinas CA, Cook SA, Barton PJR, MacArthur DG, Ware JS close, 2021, Characterising the loss-of-function impact of 5 ' untranslated region variants in 15,708 individuals (vol 11, 2523, 2020), Nature Communications, Vol:12, ISSN:2041-1723, Pages:1-1

Lim W-W, Corden B, Ye L, et al.Lim W-W, Corden B, Ye L, Viswanathan S, Widjaja AA, Xie C, Su L, Tee NGZ, Schafer S, Cook SA close, 2021, Antibody-mediated neutralization of IL11 signalling reduces ERK activation and cardiac fibrosis in a mouse model of severe pressure overload, Clinical and Experimental Pharmacology and Physiology, Vol:48, ISSN:0305-1870, Pages:605-613

Dong J, Viswanathan S, Adami E, et al.Dong J, Viswanathan S, Adami E, Singh BK, Chothani SP, Ng B, Lim WW, Zhou J, Tripathi M, Ko NSJ, Shekeran SG, Tan J, Lim SY, Wang M, Lio PM, Yen PM, Schafer S, Cook SA, Widjaja AA close, 2021, Hepatocyte-specific IL11 cis-signaling drives lipotoxicity and underlies the transition from NAFLD to NASH., Nat Commun, Vol:12

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