Imperial College London
Miss Sue Clark

MissSueClark

Faculty of Medicine, Department of Surgery & Cancer

Professor of Practice (Colorectal Surgery)
 
 
 
//

Contact

 

+44 (0)20 8235 4018sue.clark

 
 
//

Location

 

St Marks HospitalNorthwick Park and St Marks Site

//

Summary

 

Publications

Citation

BibTex format

@article{Stellingwerf:2016:10.1111/codi.13431,
author = {Stellingwerf, ME and Maeda, Y and Patel, U and Vaizey, CJ and Warusavitarne, J and Bemelman, WA and Clark, SK},
doi = {10.1111/codi.13431},
journal = {Colorectal Disease},
pages = {O292--O300},
title = {The role of the defaecating pouchogram in the assessment of evacuation difficulty after restorative proctocolectomy and pouch–anal anastomosis},
url = {http://dx.doi.org/10.1111/codi.13431},
volume = {18},
year = {2016}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - AIM: Restorative proctocolectomy (RPC) with ileal pouch-anal anastomosis (IPAA) is the most frequently performed operation for intractable ulcerative colitis (UC) and for many patients with familial adenomatous polyposis (FAP). It can be complicated by a functional evacuation difficulty, which is not well understood. We aimed to evaluate the role of defaecating pouchography in an attempt to assess the mechanism of evacuation difficulty in pouch patients. METHOD: All RPC patients who had had a defaecating pouchogram for evacuation difficulty at one hospital between 2006 and 2014 were retrospectively reviewed. The findings and features were correlated with the symptoms. Demographic, clinical and radiological variables were analysed. RESULTS: 87 (55 (63%) female (F)) patients of mean age of 47.6 ± 12.5 (standard deviation [SD]) years were identified. Thirty five had a mechanical outlet obstruction and 52 had no identified mechanical cause to explain the evacuation difficulty. The mean age of the 52 (33 [63%] F) patients was 48.2± 13 years. Of the 52 patients, significantly more used anti-diarrhoeal medication (p=0.029), complained of high frequency of defaecation (p=0.005), experienced a longer time to the initiation of defaecation (p=0.049) and underwent pouchoscopy (p=0.003). Biofeedback appeared to improve the symptoms in 7 of 16 patients with a non-mechanical defaecatory difficulty. The most common findings on defaecating pouchography included residual barium of more than 33% after an attempted evacuation (46%, n=24), slow evacuation (35%, n=18) and mucosal irregularity (33%, n=17). Correlation between radiological features and symptoms showed a statistically significant relationship between straining, anal pain, incontinence and urgency with patterns of anismus or pelvic floor descent or weakness seen on the defaecating pouchogram. Symptoms of incomplete evacuation, difficulty in the initiation of defaecation, high defaecatory frequency and abdominal
AU  - Stellingwerf,ME
AU  - Maeda,Y
AU  - Patel,U
AU  - Vaizey,CJ
AU  - Warusavitarne,J
AU  - Bemelman,WA
AU  - Clark,SK
DO  - 10.1111/codi.13431
EP  - 300
PY  - 2016///
SN  - 1463-1318
SP  - 292
TI  - The role of the defaecating pouchogram in the assessment of evacuation difficulty after restorative proctocolectomy and pouch–anal anastomosis
T2  - Colorectal Disease
UR  - http://dx.doi.org/10.1111/codi.13431
UR  - http://hdl.handle.net/10044/1/38553
VL  - 18
ER  -
Download