Publications
779 results found
Purkayastha S, Tilney HS, Georgiou P, et al., 2007, Laparoscopic cholecystectomy versus mini-laparotomy cholecystectomy: a meta-analysis of randomised control trials, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, Vol: 21, Pages: 1294-1300, ISSN: 0930-2794
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- Citations: 82
Warren O, Wallace S, Massey R, et al., 2007, Does systemic leukocyte filtration affect perioperative hemorrhage in cardiac surgery? A systematic review and meta-analysis, ASAIO JOURNAL, Vol: 53, Pages: 514-521, ISSN: 1058-2916
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- Citations: 10
Massey RM, Warren OJ, Szczeklik M, et al., 2007, Skeletonization of radial and gastroepiploic conduits in coronary artery bypass surgery, Journal of Cardiothoracic Surgery, Vol: 2, ISSN: 1749-8090
The use of a skeletonized internal thoracic artery in coronary artery bypass graft surgery has been shown to confer certain advantages over a traditional pedicled technique, particularly in certain patient groups. Recent reports indicate that radial and gastroepiploic arteries can also be harvested using a skeletonized technique. The aim of this study is to systematically review the available evidence regarding the use of skeletonized radial and gastroepiploic arteries within coronary artery bypass surgery, focusing specifically on it's effect on conduit length and flow, levels of endothelial damage, graft patency and clinical outcome. Four electronic databases were systematically searched for studies reporting the utilisation of the skeletonization technique within coronary revascularisation surgery in humans. Reference lists of all identified studies were checked for any missing publications. There appears to be some evidence that skeletonization may improve angiographic patency, when compared with pedicled vessels in the short to mid-term. We have found no suggestion of increased complication rates or increased operating time. Skeletonization may increase the length of the conduit, and the number of sequential graft sites, but no clear clinical benefits are apparent. Our study suggests that there is not enough high quality or consistent evidence to currently advocate the application of this technique to radial or gastroepiploic conduits ahead of a traditional pedicled technique.
Purkayastha S, Tekkis PP, Athanasiou T, et al., 2007, Diagnostic precision of magnetic resonance imaging for preoperative prediction of the circumferential margin involvement in patients with rectal cancer, COLORECTAL DISEASE, Vol: 9, Pages: 402-411, ISSN: 1462-8910
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- Citations: 48
Mangoush O, Purkayastha S, Haj-Yahia S, et al., 2007, Heparin-bonded circuits versus nonheparin-bonded circuits: an evaluation of their effect on clinical outcomes, EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, Vol: 31, Pages: 1058-1069, ISSN: 1010-7940
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- Citations: 59
Hadjianastassiou VG, Tekkis PP, Athanasiou T, et al., 2007, Comparison of mortality prediction models after open abdominal aortic aneurysm repair, EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY, Vol: 33, Pages: 536-543, ISSN: 1078-5884
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- Citations: 14
Chikwe J, Athanasiou T, Collins P, et al., 2007, Safety and efficacy concerns regarding elective coronary artery surgery in patients with prior coronary stents, EUROPEAN HEART JOURNAL, Vol: 28, Pages: 1265-1265, ISSN: 0195-668X
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- Citations: 1
Warren O, Alexiou C, Massey R, et al., 2007, The effects of various leukocyte filtration strategies in cardiac surgery, EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, Vol: 31, Pages: 665-676, ISSN: 1010-7940
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- Citations: 49
Kokkinos C, Athanasiou T, Rao C, et al., 2007, Does re-operation have an effect on outcome following heart transplantation?, Heart Lung Circ, Vol: 16, Pages: 93-102, ISSN: 1443-9506
OBJECTIVE: Previous cardiac operation has traditionally been considered as a potential risk factor for patients undergoing heart transplantation. This study aimed to evaluate the outcome of patients undergoing heart transplantation as a second cardiac procedure and compare it with primary heart transplantation, using meta-analytical methodology. METHODS: A literature search was undertaken to identify relevant comparative studies. Outcomes of interest were classified into four categories: (a) intra-operative times; (b) post-operative outcomes; (c) resources; (d) actuarial outcomes. RESULTS: Seven studies matched the selection criteria, reporting on 1004 patients. Six hundred and twenty-three had transplantation as primary operation and 381 as re-operation. The 1-year, 2-year, and 5-year mortality were similar for the two groups (HR=0.85, p=0.54; HR=0.97, p=0.88; and HR=1.04, p=0.92, respectively). Total operative, cold-ischaemic, by-pass, and cross-clamp times were significantly longer for the re-operation group by 59.44 (p<0.001), 14.62 (p=0.05), 25.24 (p<0.001), and 7.93 (p<0.001)min, respectively. Both ICU and hospital stay were longer for the re-operation group but only the former was statistically significant (WMD=1.37; p=0.02). Post-operative complications were similar, except re-exploration rate and blood transfusion requirement, which were higher in the re-operation group (OR=3.51; p<0.001 and WMD=2.21; p<0.001, respectively). CONCLUSIONS: Heart transplantation following previous cardiac operation is technically demanding requiring longer operative times compared to primary heart transplantation. It does not, however, add a significant risk to the survival of the patient, and associated morbidity is not significantly compromised.
Aziz O, Rao C, Panesar SS, et al., 2007, Meta-analysis of minimally invasive internal thoracic artery bypass versus percutaneous revascularisation for isolated lesions of the left anterior descending artery, BMJ-BRITISH MEDICAL JOURNAL, Vol: 334, Pages: 617-621, ISSN: 1756-1833
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- Citations: 87
Rao C, Aziz O, Panesar SS, et al., 2007, Cost effectiveness analysis of minimally invasive internal thoracic artery bypass versus percutaneous revascularisation for isolated lesions of the left anterior descending artery, BMJ-BRITISH MEDICAL JOURNAL, Vol: 334, Pages: 621-624, ISSN: 1756-1833
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- Citations: 28
Mayer EK, Purkayastha S, Athanasiou T, et al., 2007, Redefining quality of care, JOURNAL OF THE ROYAL SOCIETY OF MEDICINE, Vol: 100, Pages: 122-124, ISSN: 0141-0768
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- Citations: 4
Tsoli E, Tsantoulis PK, Papalambros A, et al., 2007, Simultaneous evaluation of maspin and CXCR4 in patients with breast cancer, JOURNAL OF CLINICAL PATHOLOGY, Vol: 60, Pages: 261-266, ISSN: 0021-9746
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- Citations: 14
Purkayastha S, Athanasiou T, Tekkis PP, et al., 2007, Magnetic Resonance Colonography Versus Computed Tomography Colonography for the Diagnosis of Colorectal Cancer: An Indirect Comparison., Association of Coloproctology of Great Britain and Ireland
Warren O, Mandal K, Hadjianastassiou V, et al., 2007, Recombinant activated factor VII in cardiac surgery: A systematic review, ANNALS OF THORACIC SURGERY, Vol: 83, Pages: 707-714, ISSN: 0003-4975
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- Citations: 99
Purkayastha S, Athanasiou T, Tekkis PP, et al., 2007, Magnetic resonance colonography <i>vs</i> computed tomography colonography for the diagnosis of colorectal cancer:: an indirect comparison, COLORECTAL DISEASE, Vol: 9, Pages: 100-111, ISSN: 1462-8910
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- Citations: 16
Protopapas AD, Rao C, Choong A, et al., 2007, Combined sterno-clavicular approach as an alternative technique in hybrid exclusion of aortic arch aneurysm, JOURNAL OF CARDIOTHORACIC SURGERY, Vol: 2, ISSN: 1749-8090
Jones CM, Athanasiou T, Dunne N, et al., 2007, Multi-detector computed tomography in coronary artery bypass graft assessment: A meta-analysis, ANNALS OF THORACIC SURGERY, Vol: 83, Pages: 341-348, ISSN: 0003-4975
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- Citations: 38
Aziz O, Rahman MS, Hadjianastassiou VG, et al., 2007, Novel applications of Dermabond (2-octyl -cyanoacrylate) in cardiothoracic surgery., Surg Technol Int, Vol: 16, Pages: 46-51, ISSN: 1090-3941
Dermabond (Ethicon Inc., Somerville, NJ, USA) is a cyanoacrylate adhesive normally indicated for skin wound closure. This study describes the emergency use of this adhesive to control bleeding close to coronary anastomoses in exceptional cases. Dermabond was used in 17 patients who underwent cardiac surgery during an eight-month period, where other haemostatic interventions were unsuitable. It was applied for haemorrhage in 15 patients and control air leaks in two of the patients. Haemostasis was successful with Dermabond alone in 11 patients; the remaining four required additional interventions. It effectively controlled haemorrhage from ventricular pacing wires, vascular sling holes, peri-anastomotic bleeding, and epicardial tears. The adhesive was not placed directly on any graft because of embolic risk. In the two patients with visible air leaks, it was successfully used. No patient events were recorded as a result of haemorrhage and no reported toxicity. Dermabond may be indicated in circumstances in which haemostasis with traditional methods has failed or is inappropriate. A need for further high-quality objective research exists on the effectiveness and long-term safety of 2-octyl cyanoacrylate in cardiac surgery.
Constantinides VA, Tekkis PP, Fazil A, et al., 2006, Fast-track failure after cardiac surgery: Development of a prediction model, CRITICAL CARE MEDICINE, Vol: 34, Pages: 2877-2884, ISSN: 0090-3493
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- Citations: 41
Panesar SS, Athanasiou T, Nair S, et al., 2006, Early outcomes in the elderly: a meta-analysis of 4921 patients undergoing coronary artery bypass grafting - comparison between off-pump and on-pump techniques, HEART, Vol: 92, Pages: 1808-1816, ISSN: 1355-6037
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- Citations: 98
Sains PS, Tilney HS, Purkayastha S, et al., 2006, Outcomes following laparoscopic versus open repair of incisional hernia, WORLD JOURNAL OF SURGERY, Vol: 30, Pages: 2056-2064, ISSN: 0364-2313
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- Citations: 38
Purkayastha S, Tekkis PP, Lanitis S, et al., 2006, A comparison of segmental vs subtotal/total colectomy for colonic Crohn's disease: a meta-analysis., Colorectal Dis, Vol: 8, Pages: 723-724, ISSN: 1462-8910
Purpose: To evaluate differences in short- and long-term outcomes of patients with colonic Crohn's disease (CD) undergoing either subtotal/total colectomy with ileorectal anastomosis (IRA) or segmental colectomy(SC). Method: Comparative studies from 1988 to 2002, of subtotal/total colectomy and IRA vs SC, were used. The study end points included surgical and overall recurrence, time to recurrence, postoperative morbidity and incidence of permanent stoma. Meta-analytical tools were used to evaluate the study outcomes. Results: Six studies, consisting of a total of 488 patients (223-IRA and 265-SC) were included. Meta-analysis suggested no significant difference between IRA and SC in recurrence of CD. Time to recurrence was longer in the IRA group by 4.4 years (95%CI, 3.1-5.8), P < 0.001. There was no difference in postoperative complications (OR = 1.4, 95%CI, 0.16-12.74) or the need for a permanent stoma between the two groups (OR = 2.75, 95%CI, 0.78-9.71). Patients with two or more colonic segments involved were associated with lower re-operation rate in the IRA group, a difference which did not reach statistical significance (P = 0.177). Conclusions: Both procedures were equally effective as treatment options for colonic CD, however, patients in the SC group exhibited recurrence earlier than those in the IRA group. The choice of operation is dependent on the extent of colonic disease, with a trend towards better outcomes with IRA for two or more colonic segments involved.
Lovegrove RE, Tilney HS, Heriot AG, et al., 2006, A comparison of adverse events and functional outcomes after restorative proctocolectomy for familial adenomatous polyposis and ulcerative colitis, DISEASES OF THE COLON & RECTUM, Vol: 49, Pages: 1293-1306, ISSN: 0012-3706
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- Citations: 66
Purkayastha S, Chow A, Athanasiou T, et al., 2006, Does serum procalcitonin have a role in evaluating the severity of acute pancreatitis? A question revisited, WORLD JOURNAL OF SURGERY, Vol: 30, Pages: 1713-1721, ISSN: 0364-2313
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- Citations: 23
Jones CM, Athanasiou T, Dunne N, et al., 2006, Multi-slice computed tomography in coronary artery diseasel, EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, Vol: 30, Pages: 443-450, ISSN: 1010-7940
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- Citations: 17
Panesar SS, Thakrar R, Athanasiou T, et al., 2006, Comparison of reports of randomized controlled trials and systematic reviews in surgical journals: literature review, JOURNAL OF THE ROYAL SOCIETY OF MEDICINE, Vol: 99, Pages: 470-472, ISSN: 0141-0768
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- Citations: 38
O'Flynn E, Purkayastha S, Athanasiou T, et al., 2006, Repair of a giant left ventricular pseudoaneurysm in a Jehovah's Witness., Asian Cardiovasc Thorac Ann, Vol: 14, Pages: 328-330
We report the successful surgical management of a giant chronic left ventricular pseudoaneurysm that developed after an inferior myocardial infarction in a 71-year-old female Jehovah's Witness. The case presented a highly risky challenge to the surgeon because of the faith's stance of refusing blood transfusion.
Constantinides VA, Tekkis PP, Athanasiou T, et al., 2006, Primary resection with anastomosis <i>vs</i>. Hartmann's procedure in nonelective surgery for acute colonic diverticulitis:: A systematic review, DISEASES OF THE COLON & RECTUM, Vol: 49, Pages: 966-981, ISSN: 0012-3706
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- Citations: 163
Tilney HS, Constantinides VA, Heriot AG, et al., 2006, Comparison of laparoscopic and open ileocecal resection for Crohn's disease: a metaanalysis, SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES, Vol: 20, Pages: 1036-1044, ISSN: 0930-2794
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- Citations: 135
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