Imperial College London
Alternate

ProfessorTimBarraclough

Faculty of Natural Sciences, Department of Life Sciences (Silwood Park)

Visiting Professor
 
 
 
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Contact

 

+44 (0)20 7594 2247t.barraclough Website

 
 
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Location

 

N2.4Silwood ParkSilwood Park

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Summary

 

Publications

Citation

BibTex format

@article{Barraclough:2018:10.1371/journal.pbio.2004830,
author = {Barraclough, TG and Nowell, R and Wilson, C and Smith, T},
doi = {10.1371/journal.pbio.2004830},
journal = {PLoS Biology},
title = {Comparative genomics of bdelloid rotifers: insights from desiccating and nondesiccating species},
url = {http://dx.doi.org/10.1371/journal.pbio.2004830},
volume = {16},
year = {2018}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Bdelloid  rotifers  are a  Class  of microscopic  invertebrates  that  have  existed  for  millions  of  years apparently  without  sex  or  meiosis.  They  inhabit  a  variety  of  temporary  and permanent  freshwater habitats  globally,  and  many  species  are  remarkably  tolerant  of  desiccation.  Bdelloids  offer  an opportunity  to  better  understand  the  evolution  of  sex  and  recombination,  but  previous  work  has  emphasized  desiccation  as  the  cause  of  several  unusual  genomic  features  in  this  group.  Here,  we present high-quality whole genome sequences of three bdelloid species: Rotaria macrura and Rotaria  magnacalcarata, which  are  both  desiccation  intolerant,  and Adineta  ricciae,  which  is  desiccationtolerant.  In  combination  with  the  published  assembly  of Adineta  vaga,  which  is  also  desiccation tolerant, we apply a comparative genomics approach to evaluate the potential effects of desiccation tolerance  and  asexuality  on  genome  evolution  in  bdelloids.  We  find  that  ancestral  tetraploidy  is conserved  among  all  four  bdelloid  species,  but  homologous  divergence  in  obligately  aquatic Rotaria genomes  is  unexpectedly  low.  This  finding  is  contrary  to  current  models  regarding  the  role  of desiccation in shaping bdelloid genomes. In addition, we find that homologous regions in A. ricciaeare largely collinear and do not form palindromic repeats as observed in the published A. vaga assembly. Consequently,  several  features  interpreted  as  genomic  evidence  for  long-term  ameiotic evolution are not general to all bdelloid species, even within the same genus. Finally, we substantiate previous 50 findings  of  high  levels  of  horizontally  transferred  non-metazoan  genes  in  both  desiccating  and  non-desiccating bdelloid species, and show that this unusual feature is not shared by other animal phyla, even  those  with  desiccation-tolerant  representatives.  These  comparisons  call
AU  - Barraclough,TG
AU  - Nowell,R
AU  - Wilson,C
AU  - Smith,T
DO  - 10.1371/journal.pbio.2004830
PY  - 2018///
SN  - 1544-9173
TI  - Comparative genomics of bdelloid rotifers: insights from desiccating and nondesiccating species
T2  - PLoS Biology
UR  - http://dx.doi.org/10.1371/journal.pbio.2004830
UR  - http://hdl.handle.net/10044/1/58323
VL  - 16
ER  -
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