Imperial College London

Dipl. Psych. Tobias Buchborn

Faculty of MedicineDepartment of Brain Sciences

Honorary Research Fellow



+44 (0)20 7594 3205t.buchborn




Burlington DanesHammersmith Campus





  • Tobias Buchborn graduated in Psychology at the Otto-von-Guericke University in Magdeburg, Germany. In his Diploma thesis, he investigated the behavioural and pharmacodynamic effects of the 5-HT1A/2A agonist LSD on bulbectomised rats, an animal model of depression.
  • Tobias ran his PhD project in Biology (dspln. Neuroscience) at the Institute of Pharmacology and Toxicology in Magdeburg. Here, his research addressed the behavioural and molecular biological correlates of differential tolerance to LSD and DMT, with focus on processes of 5-HT2A regulation.
  • In 2016, Tobias was awarded an MSCA Individual Research Fellowship and started to work at Imperial's Department of Medicine, Laboratory for Neuronal Circuit Dynamics (LNCD). Ever since, his research has been devoted to the corticodynamics of serotonergic hallucinogen action.

Further inormation



Buchborn T, Lyons T, Knopfel T, 2018, Tolerance and Tachyphylaxis to Head Twitches Induced by the 5-HT2A Agonist 25CN-NBOH in Mice, Frontiers in Pharmacology, Vol:9, ISSN:1663-9812

Buchborn T, Schroeder H, Dieterich DC, et al., 2015, Tolerance to LSD and DOB induced shaking behaviour: Differential adaptations of frontocortical 5-HT2A and glutamate receptor binding sites, Behavioural Brain Research, Vol:281, ISSN:0166-4328, Pages:62-68

Buchborn T, Schroeder H, Hoellt V, et al., 2014, Repeated lysergic acid diethylamide in an animal model of depression: Normalisation of learning behaviour and hippocampal serotonin 5-HT2 signalling, Journal of Psychopharmacology, Vol:28, ISSN:0269-8811, Pages:545-552


Buchborn T, Schroeder H, Koch T, et al., 2016, Differential tolerance to lysergic acid diethylamide (LSD) and dimethyltryptamine (DMT) - A matter of serotonin (5-HT) 2A receptor downregulation?, 82nd Annual Meeting of the German-Society-for-Exerimental-and-Clinical-Pharmacology-and-Toxicology (DGPT) / 18th Annual Meeting of the Network-Clinical-Pharmacology-Germany (VKliPha), SPRINGER, Pages:S63-S63, ISSN:0028-1298

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