Imperial College London
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Dr. Tobias Buchborn, Dipl. Psych.

Faculty of Medicine, Department of Brain Sciences

Honorary Research Fellow
 
 
 
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Contact

 

+44 (0)20 7594 3205t.buchborn

 
 
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Location

 

Burlington DanesHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Kaertner:2021:10.1038/s41598-021-81446-7,
author = {Kaertner, L and Steinborn, M and Kettner, H and Spriggs, M and Roseman, L and Buchborn, T and Timmermann, Slater C and Erritzoe, D and Carhart-Harris, R},
doi = {10.1038/s41598-021-81446-7},
journal = {Scientific Reports},
title = {Positive expectations predict improved mental-health outcomes linked to psychedelic microdosing},
url = {http://dx.doi.org/10.1038/s41598-021-81446-7},
volume = {11},
year = {2021}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Psychedelic microdosing describes the ingestion of near-threshold perceptible doses of classicpsychedelic substances. Anecdotal reports and observational studies suggest that microdosingmay promote positive mood and well-being, but recent placebo-controlled studies failed to fndcompelling evidence for this. The present study collected web-based mental health and related datausing a prospective (before, during and after) design. Individuals planning a weekly microdosingregimen completed surveys at strategic timepoints, spanning a core four-week test period. Eightyone participants completed the primary study endpoint. Results revealed increased self-reportedpsychological well-being, emotional stability and reductions in state anxiety and depressivesymptoms at the four-week primary endpoint, plus increases in psychological resilience, socialconnectedness, agreeableness, nature relatedness and aspects of psychological fexibility. However,positive expectancy scores at baseline predicted subsequent improvements in well-being, suggestiveof a signifcant placebo response. This study highlights a role for positive expectancy in predictingpositive outcomes following psychedelic microdosing and cautions against zealous inferences on itsputative therapeutic value.
AU  - Kaertner,L
AU  - Steinborn,M
AU  - Kettner,H
AU  - Spriggs,M
AU  - Roseman,L
AU  - Buchborn,T
AU  - Timmermann,Slater C
AU  - Erritzoe,D
AU  - Carhart-Harris,R
DO  - 10.1038/s41598-021-81446-7
PY  - 2021///
SN  - 2045-2322
TI  - Positive expectations predict improved mental-health outcomes linked to psychedelic microdosing
T2  - Scientific Reports
UR  - http://dx.doi.org/10.1038/s41598-021-81446-7
UR  - https://www.nature.com/articles/s41598-021-81446-7
UR  - http://hdl.handle.net/10044/1/86428
VL  - 11
ER  -
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