Imperial College London
Portrait Picture

Professor Tony Cass

Faculty of Natural Sciences, Department of Chemistry

Senior Research Investigator
 
 
 
//

Contact

 

+44 (0)20 7594 5195t.cass

 
 
//

Location

 

301KMolecular Sciences Research HubWhite City Campus

//

Summary

 

Publications

Citation

BibTex format

@article{Luu:2019:10.1071/ch19238,
author = {Luu, T and Liu, M and Chen, Y and Hushiarian, R and Cass, A and Tang, BZ and Hong, Y},
doi = {10.1071/ch19238},
journal = {Australian Journal of Chemistry},
pages = {620--620},
title = {Aptamer-Based Biosensing with a Cationic AIEgen},
url = {http://dx.doi.org/10.1071/ch19238},
volume = {72},
year = {2019}
}
Download

RIS format (EndNote, RefMan)

TY  - JOUR
AB  - <jats:p>Fabrication of low-cost biosensing platforms with high selectivity and sensitivity is important for constructing portable devices for personal health monitoring. Herein, we report a simple biosensing strategy based on the combination of a cationic AIEgen (aggregation-induced emission fluorogen), TPE-2+, with an aptamer for specific protein detection. The target protein can displace the dye molecules on the dye–aptamer complex, resulting in changes in the fluorescence signal. Selectivity towards different targets can be achieved by simply changing the aptamer sequence. The working mechanism is also investigated.</jats:p>
AU  - Luu,T
AU  - Liu,M
AU  - Chen,Y
AU  - Hushiarian,R
AU  - Cass,A
AU  - Tang,BZ
AU  - Hong,Y
DO  - 10.1071/ch19238
EP  - 620
PY  - 2019///
SN  - 0004-9425
SP  - 620
TI  - Aptamer-Based Biosensing with a Cationic AIEgen
T2  - Australian Journal of Chemistry
UR  - http://dx.doi.org/10.1071/ch19238
VL  - 72
ER  -
Download