Imperial College London
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Professor Tony Cass

Faculty of Natural Sciences, Department of Chemistry

Senior Research Investigator
 
 
 
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Contact

 

+44 (0)20 7594 5195t.cass

 
 
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Location

 

301KMolecular Sciences Research HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Le:2014:10.1039/c4cc07888h,
author = {Le, TT and Adamiak, B and Benton, DJ and Johnson, CJ and Sharma, S and Fenton, R and McCauley, JW and Iqbal, M and Cass, AEG},
doi = {10.1039/c4cc07888h},
journal = {CHEMICAL COMMUNICATIONS},
pages = {15533--15536},
title = {Aptamer-based biosensors for the rapid visual detection of flu viruses},
url = {http://dx.doi.org/10.1039/c4cc07888h},
volume = {50},
year = {2014}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - RNA aptamers showing affinity and specificity for different strains of human influenza virus were assembled onto gold nanoparticles that subsequently formed a gold nanoshell (AuNS) around the viral envelope. These shells could be visualised by transmission electron microscopy (TEM). Changes in size and structure of the AuNS coated virus can be used to detect the viruses. We show that sedimentation with a low cost centrifuge and visual determination can detect 3 × 108 viral particles.
AU  - Le,TT
AU  - Adamiak,B
AU  - Benton,DJ
AU  - Johnson,CJ
AU  - Sharma,S
AU  - Fenton,R
AU  - McCauley,JW
AU  - Iqbal,M
AU  - Cass,AEG
DO  - 10.1039/c4cc07888h
EP  - 15536
PY  - 2014///
SN  - 1359-7345
SP  - 15533
TI  - Aptamer-based biosensors for the rapid visual detection of flu viruses
T2  - CHEMICAL COMMUNICATIONS
UR  - http://dx.doi.org/10.1039/c4cc07888h
VL  - 50
ER  -
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