Imperial College London
Portrait Picture

Tom Ellis

Faculty of Engineering, Department of Bioengineering

Professor of Synthetic Genome Engineering
 
 
 
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Contact

 

+44 (0)20 7594 7615t.ellis Website CV

 
 
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Location

 

704Bessemer BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Boo:2019:10.1016/j.coisb.2019.03.001,
author = {Boo, A and Ellis, T and Stan, G},
doi = {10.1016/j.coisb.2019.03.001},
journal = {Current Opinion in Systems Biology},
pages = {66--72},
title = {Host-aware synthetic biology},
url = {http://dx.doi.org/10.1016/j.coisb.2019.03.001},
volume = {14},
year = {2019}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Unnatural gene expression imposes a load on engineered microorganisms thatdecreases their growth and subsequent production yields, a phenomenon knownasburden.  In the last decade, the field of synthetic biology has made progress onthe development of biomolecular feedback control systems and other approachesthat can improve the growth of engineered cells, as well as the genetic stability,portability and robust performance of cell-hosted synthetic constructs.  In thisreview, we highlight recent work focused on the development of host-aware syn-thetic biology.
AU  - Boo,A
AU  - Ellis,T
AU  - Stan,G
DO  - 10.1016/j.coisb.2019.03.001
EP  - 72
PY  - 2019///
SN  - 2452-3100
SP  - 66
TI  - Host-aware synthetic biology
T2  - Current Opinion in Systems Biology
UR  - http://dx.doi.org/10.1016/j.coisb.2019.03.001
UR  - http://hdl.handle.net/10044/1/68705
VL  - 14
ER  -
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