Summary
The Luis lab focuses on the role of the bone marrow microenvironment in the regulation of blood stem cell function. We are interested in decoding the molecular crosstalk between stem cells and their niches, it's role in the maintenance of homeostasis and the development of haematological malignancies.
haematopoietic stem cell niche lab
We are recruiting. Post-doctoral position will soon be advertised here.
We also welcome informal enquires about positions in the lab. If you are interested in joining the lab, please get in touch.
For more information visit our web site.
Selected Publications
Journal Articles
Carrelha J, Meng Y, Kettyle LM, et al., 2018, Hierarchically related lineage-restricted fates of multipotent haematopoietic stem cells, Nature, Vol:554, ISSN:0028-0836, Pages:106-+
Beerman I, Luis TC, Singbrant S, et al., 2017, The evolving view of the hematopoietic stem cell niche, Experimental Hematology, Vol:50, ISSN:0301-472X, Pages:22-26
Luis TC, Luc S, Mizukami T, et al., 2016, Initial seeding of the embryonic thymus by immune-restricted lympho-myeloid progenitors, Nature Immunology, Vol:17, ISSN:1529-2908, Pages:1424-1435
Luis TC, Tremblay CS, Manz MG, et al., 2016, Inflammatory signals in HSPC development and homeostasis: Too much of a good thing?, Experimental Hematology, Vol:44, ISSN:0301-472X, Pages:908-912
Sanjuan-Pla A, Macaulay IC, Jensen CT, et al., 2013, Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy, Nature, Vol:502, ISSN:0028-0836, Pages:232-+
Luis TC, Naber BAE, Roozen PPC, et al., 2011, Canonical Wnt Signaling Regulates Hematopoiesis in a Dosage-Dependent Fashion, Cell Stem Cell, Vol:9, ISSN:1934-5909, Pages:345-356