Imperial College London

ProfessorTimothyHallett

Faculty of MedicineSchool of Public Health

Professor of Global Health
 
 
 
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Contact

 

+44 (0)20 7594 1150timothy.hallett

 
 
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Location

 

Norfolk PlaceSt Mary's Campus

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Summary

 

Publications

Publication Type
Year
to

209 results found

Gregson S, Hallett TB, Stover J, Ghys PDet al., 2013, Putting the burden of HIV in context, AIDS, Vol: 27, Pages: 2161-+, ISSN: 0269-9370

Journal article

Celum C, Hallett TB, Baeten JM, 2013, HIV-1 Prevention With ART and PrEP: Mathematical Modeling Insights Into Resistance, Effectiveness, and Public Health Impact, JOURNAL OF INFECTIOUS DISEASES, Vol: 208, Pages: 189-191, ISSN: 0022-1899

Journal article

Hallett TB, Eaton JW, 2013, A Side Door Into Care Cascade for HIV-Infected Patients?, JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, Vol: 63, Pages: S228-S232, ISSN: 1525-4135

Journal article

Vesga JF, Boily MC, Hallett TB, 2013, ESTIMATING THE IMPACT OF ANTIRETROVIRAL THERAPY AND CONDOMS IN THE HIV EPIDEMIC OF BOGOTA, COLOMBIA, SEXUALLY TRANSMITTED INFECTIONS, Vol: 89, Pages: A281-A281, ISSN: 1368-4973

Journal article

Alsallaq R, Buttolph J, Cleland C, Hallett T, Kurth Aet al., 2013, ESTIMATING THE IMPACT OF COMBINED PREVENTION INTERVENTIONS TARGETING 15-24 YEARS-OLD MEN AND WOMEN IN NYANZA, KENYA, SEXUALLY TRANSMITTED INFECTIONS, Vol: 89, Pages: A269-A269, ISSN: 1368-4973

Journal article

Elmes J, Nhongo K, Hallett T, White P, Ward H, Garnett G, Nyamukapa C, Gregson Set al., 2013, THE SOCIAL ORGANISATION OF SEX WORK IN RURAL EASTERN ZIMBABWE AND ITS IMPLICATIONS FOR HIV INFECTION, SEXUALLY TRANSMITTED INFECTIONS, Vol: 89, Pages: A179-A180, ISSN: 1368-4973

Journal article

Elmes J, Nhongo K, Hallett T, White P, Ward H, Garnett G, Nyamukapa C, Gregson Set al., 2013, THE PRICE OF SEX: INSIGHTS INTO THE DETERMINANTS OF THE PRICE OF COMMERCIAL SEX AMONG FEMALE SEX WORKERS IN RURAL ZIMBABWE, SEXUALLY TRANSMITTED INFECTIONS, Vol: 89, Pages: A39-A39, ISSN: 1368-4973

Journal article

Estill J, Egger M, Blaser N, Vizcaya LS, Garone D, Wood R, Campbell J, Hallett TB, Keiser Oet al., 2013, Cost-effectiveness of point-of-care viral load monitoring of antiretroviral therapy in resource-limited settings: mathematical modelling study, AIDS, Vol: 27, Pages: 1483-1492, ISSN: 0269-9370

Journal article

Estill J, Egger M, Johnson LF, Gsponer T, Wandeler G, Davies M-A, Boulle A, Wood R, Garone D, Stringer JSA, Hallett TB, Keiser Oet al., 2013, Monitoring of Antiretroviral Therapy and Mortality in HIV Programmes in Malawi, South Africa and Zambia: Mathematical Modelling Study, PLOS ONE, Vol: 8, ISSN: 1932-6203

Journal article

Cremin I, Alsallaq R, Dybul M, Piot P, Garnett G, Hallett TBet al., 2013, The new role of antiretrovirals in combination HIV prevention: a mathematical modelling analysis, AIDS, Vol: 27, Pages: 447-458, ISSN: 0269-9370

Journal article

Alsallaq RA, Baeten JM, Celum CL, Hughes JP, Abu-Raddad LJ, Barnabas RV, Hallett TBet al., 2013, Understanding the Potential Impact of a Combination HIV Prevention Intervention in a Hyper-Endemic Community, PLOS ONE, Vol: 8, ISSN: 1932-6203

Journal article

Chemaitelly H, Shelton JD, Hallett TB, Abu-Raddad LJet al., 2013, Only a fraction of new HIV infections occur within identifiable stable discordant couples in sub-Saharan Africa, AIDS, Vol: 27, Pages: 251-260, ISSN: 0269-9370

Journal article

Butler AR, Smith JA, Polis CB, Gregson S, Stanton D, Hallett TBet al., 2013, Modelling the global competing risks of a potential interaction between injectable hormonal contraception and HIV risk, AIDS, Vol: 27, Pages: 105-113, ISSN: 0269-9370

Background: Some, but not all, observational studies have suggested an increase in the risk of HIV acquisition for women using injectable hormonal contraception (IHC).Methods: We used country-level data to explore the effects of reducing IHC use on the number of HIV infections, the number of live births and the resulting net consequences on AIDS deaths and maternal mortality for each country.Results: High IHC use coincides with high HIV incidence primarily in southern and eastern Africa. If IHC increases the risk of HIV acquisition, this could generate 27 000–130 000 infections per year globally, 87–88% of which occur in this region. Reducing IHC use could result in fewer HIV infections but also a substantial increase in live births and maternal mortality in countries with high IHC use, high birth rates and high maternal mortality: mainly southern and eastern Africa, South-East Asia, and Central and South America. For most countries, the net impact of reducing IHC use on maternal and AIDS-related deaths is dependent on the magnitude of the assumed IHC–HIV interaction.Conclusions: If IHC use increases HIV acquisition risk, reducing IHC could reduce new HIV infections; however, this must be balanced against other important consequences, including unintended pregnancy, which impacts maternal and infant mortality. Unless the true effect size approaches a relative risk of 2.19, it is unlikely that reductions in IHC could result in public health benefit, with the possible exception of those countries in southern Africa with the largest HIV epidemics.

Journal article

Wheelock A, Eisingerich AB, Ananworanich J, Gomez GB, Hallett TB, Dybul MR, Piot Pet al., 2013, Are Thai MSM Willing to Take PrEP for HIV Prevention? An Analysis of Attitudes, Preferences and Acceptance, Plos One, Vol: 8(1)e54288

Journal article

Eaton JW, Hallett TB, Epstein H, 2012, What Might be the Impact of Sexual Partnership "Concurrency'' Behavior Change Communication Campaigns?, SEXUALLY TRANSMITTED DISEASES, Vol: 39, Pages: 899-899, ISSN: 0148-5717

Journal article

Case KK, Ghys PD, Gouws E, Eaton JW, Borquez A, Stover J, Cuchi P, Abu-Raddad LJ, Garnett GP, Hallett TBet al., 2012, Understanding the modes of transmission model of new HIV infection and its use in prevention planning, BULLETIN OF THE WORLD HEALTH ORGANIZATION, Vol: 90, Pages: 831-838, ISSN: 0042-9686

Journal article

Hontelez JAC, Lurie MN, Baernighausen T, Bakker R, Baltussen R, Tanser F, Hallett TB, Newell M-L, de Vlas SJet al., 2012, Treatment as prevention for HIV in South Africa: different models show consistency in occurrence, but difference in timing of elimination and the overall impact of the intervention, JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, Vol: 15, Pages: 113-116

Journal article

Gomez GB, Borquez A, Caceres CF, Segura ER, Grant RM, Garnett GP, Hallett TBet al., 2012, The Potential Impact of Pre-Exposure Prophylaxis for HIV Prevention among Men Who Have Sex with Men and Transwomen in Lima, Peru: A Mathematical Modelling Study, PLOS MEDICINE, Vol: 9, ISSN: 1549-1676

Journal article

Escaleira F, Birger R, Hallett T, Grenfell B, Hodder S, Sinha Aet al., 2012, Cost-effectiveness of test and treat prevention in a high HIV prevalence US city, JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, Vol: 15, Pages: 256-257

Journal article

Smit M, Smit C, Cremin I, Garnett GP, Hallett T, de Wolf Fet al., 2012, Could better tolerated HIV drug regimens improve patient outcome?, AIDS, Vol: 26, Pages: 1953-1959, ISSN: 0269-9370

Journal article

Estill J, Aubriere C, Egger M, Johnson L, Wood R, Garone D, Gsponer T, Wandeler G, Boulle A, Davies M-A, Hallett TB, Keiser Oet al., 2012, Viral load monitoring of antiretroviral therapy, cohort viral load and HIV transmission in Southern Africa: a mathematical modelling analysis, AIDS, Vol: 26, Pages: 1403-1413, ISSN: 0269-9370

Journal article

HIV Modelling Consortium Treatment as Prevention Editorial Writing Group, 2012, HIV treatment as prevention: models, data, and questions--towards evidence-based decision-making., PLOS Medicine, Vol: 9, ISSN: 1549-1277

Antiretroviral therapy (ART) for those infected with HIV can prevent onward transmission of infection, but biological efficacy alone is not enough to guide policy decisions about the role of ART in reducing HIV incidence. Epidemiology, economics, demography, statistics, biology, and mathematical modelling will be central in framing key decisions in the optimal use of ART. PLoS Medicine, with the HIV Modelling Consortium, has commissioned a set of articles that examine different aspects of HIV treatment as prevention with a forward-looking research agenda. Interlocking themes across these articles are discussed in this introduction. We hope that this article, and others in the collection, will provide a foundation upon which greater collaborations between disciplines will be formed, and will afford deeper insights into the key factors involved, to help strengthen the support for evidence-based decision-making in HIV prevention.

Journal article

Delva W, Eaton JW, Meng F, Fraser C, White RG, Vickerman P, Boily M-C, Hallett TBet al., 2012, HIV Treatment as Prevention: Optimising the Impact of Expanded HIV Treatment Programmes, PLOS Medicine, Vol: 9, ISSN: 1549-1277

Until now, decisions about how to allocate ART have largely been based on maximising the therapeutic benefit of ART for patients. Since the results of the HPTN 052 study showed efficacy of antiretroviral therapy (ART) in preventing HIV transmission, there has been increased interest in the benefits of ART not only as treatment, but also in prevention. Resources for expanding ART in the short term may be limited, so the question is how to generate the most prevention benefit from realistic potential increases in the availability of ART. Although not a formal systematic review, here we review different ways in which access to ART could be expanded by prioritising access to particular groups based on clinical or behavioural factors. For each group we consider (i) the clinical and epidemiological benefits, (ii) the potential feasibility, acceptability, and equity, and (iii) the affordability and cost-effectiveness of prioritising ART access for that group. In re-evaluating the allocation of ART in light of the new data about ART preventing transmission, the goal should be to create policies that maximise epidemiological and clinical benefit while still being feasible, affordable, acceptable, and equitable.

Journal article

Boily M-C, Masse B, Alsallaq R, Padian NS, Eaton JW, Vesga JF, Hallett TBet al., 2012, HIV Treatment as Prevention: Considerations in the Design, Conduct, and Analysis of Cluster Randomized Controlled Trials of Combination HIV Prevention, PLOS Medicine, Vol: 9, ISSN: 1549-1277

Journal article

Johnson LF, Hallett TB, Rehle TM, Dorrington REet al., 2012, The effect of changes in condom usage and antiretroviral treatment coverage on human immunodeficiency virus incidence in South Africa: a model-based analysis, JOURNAL OF THE ROYAL SOCIETY INTERFACE, Vol: 9, Pages: 1544-1554, ISSN: 1742-5689

Journal article

Eaton JW, Johnson LF, Salomon JA, Baernighausen T, Bendavid E, Bershteyn A, Bloom DE, Cambiano V, Fraser C, Hontelez JAC, Humair S, Klein DJ, Long EF, Phillips AN, Pretorius C, Stover J, Wenger EA, Williams BG, Hallett TBet al., 2012, HIV Treatment as Prevention: Systematic Comparison of Mathematical Models of the Potential Impact of Antiretroviral Therapy on HIV Incidence in South Africa, PLOS MEDICINE, Vol: 9, ISSN: 1549-1277

Journal article

Delva W, Wilson DP, Abu-Raddad L, Gorgens M, Wilson D, Hallett TB, Welte Aet al., 2012, HIV Treatment as Prevention: Principles of Good HIV Epidemiology Modelling for Public Health Decision-Making in All Modes of Prevention and Evaluation, PLOS MEDICINE, Vol: 9, ISSN: 1549-1277

Journal article

Hewett PC, Hallett TB, Mensch BS, Dzekedzeke K, Zimba-Tembo S, Garnett GP, Todd PEet al., 2012, Sex with stitches: assessing the resumption of sexual activity during the postcircumcision wound-healing period, AIDS, Vol: 26, Pages: 749-756, ISSN: 0269-9370

Journal article

Chemaitelly H, Cremin I, Shelton J, Hallett TB, Abu-Raddad LJet al., 2012, Distinct HIV discordancy patterns by epidemic size in stable sexual partnerships in sub-Saharan Africa, SEXUALLY TRANSMITTED INFECTIONS, Vol: 88, Pages: 51-57, ISSN: 1368-4973

Journal article

Hallett TB, Gregson S, Dube S, Mapfeka ES, Mugurungi O, Garnett GPet al., 2011, Estimating the resources required in the roll-out of universal access to antiretroviral treatment in Zimbabwe, SEXUALLY TRANSMITTED INFECTIONS, Vol: 87, Pages: 621-628, ISSN: 1368-4973

Journal article

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