Imperial College London

DrVassilikiKoufopanou

Faculty of Natural SciencesDepartment of Life Sciences (Silwood Park)

Research Fellow
 
 
 
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Contact

 

+44 (0)20 7594 2381v.koufopanou

 
 
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Location

 

W3.2Silwood ParkSilwood Park

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Summary

 

Summary

Research

My research is in evolutionary and population genetics, using the yeasts as a model system to study:

  • genome evolution
  • evolution and domestication of selfish genetic elements
  • horizontal transfer of genes
  • species diversity and phylogenetics

Selected Publications

  • Tsai I.J., A. Burt and V. Koufopanou (2010) Conservation of recombination hotspots in yeast. Proc Natl Acad Sci USA 107:7847-7852 (doi)
  • Tsai, I. J., D. Bensasson, A. Burt and V. Koufopanou (2008) Population genomics of a wild yeast: quantifying the life cycle. Proc. Natl. Acad. Sci. USA 105:4957-4962 (doi)
  • Bensasson, D., M. Zarowiecki, A. Burt and V. Koufopanou (2008). Rapid evolution of yeast centromeres in the absence of drive. Genetics Vol:178, Pages:2161-2167(doi)
  • Koufopanou, V. J. Hughes, G. Bell and A. Burt (2006). The spatial scale of genetic differentiation in a model organism: the wild yeast Saccharomyces paradoxus. Phil. Trans. Roy. Soc. London B 361:1941-1946 (doi)
  • Koufopanou, V. and A. Burt (2005). Degeneration and domestication of a selfish gene in yeast: molecular evolution versus site-directed mutagenesis. Molecular Biology and Evolution 22: 1535-1538 (doi)
  • Burt, A. and V. Koufopanou (2004). Homing endonuclease genes: the rise and fall and rise again of a selfish element. Current Opinion in Genetics & Development 14: 609-615 (doi)
  • Johnson, L. J., V. Koufopanou, et al. (2004). Population genetics of the wild yeast Saccharomyces paradoxus. Genetics 166: 43-52.
  • Leroi, A., V. Koufopanou, and A. Burt. (2003). Cancer selection. Nature Reviews, Cancer 3: 226-231 (doi)

Publications

Journals

Koufopanou V, Lomas S, Tsai IJ, et al., 2015, Estimating the Fitness Effects of New Mutations in the Wild Yeast Saccharomyces paradoxus, Genome Biology and Evolution, Vol:7, ISSN:1759-6653, Pages:1887-1895

Harrison E, MacLean RC, Koufopanou V, et al., 2014, Sex drives intracellular conflict in yeast, Journal of Evolutionary Biology, Vol:27, ISSN:1010-061X, Pages:1757-1763

Koufopanou V, Swire J, Lomas S, et al., 2013, Primers for fourteen protein-coding genes and the deep phylogeny of the true yeasts, Fems Yeast Research, Vol:13, ISSN:1567-1356, Pages:574-584

Harrison E, Koufopanou V, Burt A, et al., 2012, The cost of copy number in a selfish genetic element: the 2-mu M plasmid of Saccharomyces cerevisiae, Journal of Evolutionary Biology, Vol:25, ISSN:1010-061X, Pages:2348-2356

Tsai IJ, Burt A, Koufopanou V, 2010, Conservation of recombination hotspots in yeast, Proceedings of the National Academy of Sciences of the United States of America, Vol:107, ISSN:0027-8424, Pages:7847-7852

More Publications