Imperial College London
Alternate

DrWengangChai

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

Senior Research Fellow
 
 
 
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Contact

 

+44 (0)20 7594 2596w.chai

 
 
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Location

 

Burlington DanesHammersmith Campus

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Summary

 

Publications

Publication Type
Year
to

191 results found

Campanero-Rhodes MA, Crocker P, Childs RA, Chai WG, Feizi Tet al., 2005, Analyses of carbohydrate recognition by mammalian sialic acid-binding proteins of the immune system, siglecs, using microarrays of lipid-linked oligosaccharide probes, Meeting of the Society-for-Glycobiology, Publisher: OXFORD UNIV PRESS INC, Pages: 1188-1188, ISSN: 0959-6658

Conference paper

Chai WG, Piskarev VE, Zhang YB, Lawson AM, Kogelberg Het al., 2005, Structural determination of novel lacto-<i>N</i>-decaose and its monofucosylated analogue from human milk by electrospray tandem mass spectrometry and <SUP>1</SUP>H NMR spectroscopy, ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, Vol: 434, Pages: 116-127, ISSN: 0003-9861

Journal article

Chai WG, Beeson JG, Byrne TJ, Brown GV, Lawson AMet al., 2004, Towards defining binding specificities of malaria parasite <i>Plasmodium falciparum</i>-infected, Joint Meeting of the Society-for-Glycobiology/Japanese-Society-for-Carbohydrate-Research, Publisher: OXFORD UNIV PRESS INC, Pages: 1102-1103, ISSN: 0959-6658

Conference paper

Reddy ST, Chai W, Childs RA, Page JD, Feizi T, Dahms NMet al., 2004, Identification of a Low Affinity Mannose 6-Phosphate Binding Site in Domain 5 of the Cation-Independent Mannose 6-Phosphate Receptor, J Biol Chem, Vol: 279, Pages: 38658-38667, ISSN: 0021-9258

Journal article

Chai WG, Leteux C, Westling C, Lindahl U, Feizi Tet al., 2004, Relative susceptibilities of the glucosamine-glucuronic acid and <i>N</i>-acetylglucosamine-glucuronic acid linkages to heparin lyase III, BIOCHEMISTRY, Vol: 43, Pages: 8590-8599, ISSN: 0006-2960

Journal article

Feizi T, Chai WG, 2004, Oligosaccharide microarrays to decipher the glyco code, NATURE REVIEWS MOLECULAR CELL BIOLOGY, Vol: 5, Pages: 582-588, ISSN: 1471-0072

Journal article

Galustian C, Park CG, Chai WG, Kiso M, Bruening SA, Kang YS, Steinman RM, Feizi Tet al., 2004, High and low affinity carbohydrate ligands revealed for murine SIGN-R1 by carbohydrate array and cell binding approaches, and differing specificities for SIGN-R3 and langerin, INTERNATIONAL IMMUNOLOGY, Vol: 16, Pages: 853-866, ISSN: 0953-8178

Journal article

Kogelberg H, Piskarev VE, Zhang YB, Lawson AM, Chai WGet al., 2004, Determination by electrospray mass spectrometry and <SUP>1</SUP>H-NMR spectroscopy of primary structures of variously fucosylated neutral oligosaccharides based on the <i>iso</i>-lacto-<i>N</i>-octaose core, EUROPEAN JOURNAL OF BIOCHEMISTRY, Vol: 271, Pages: 1172-1186, ISSN: 0014-2956

Journal article

Reddy ST, Chai WG, Childs RA, Feizi T, Dahms NMet al., 2003, Identification of a low-affinity mannose 6-phosphate binding site in domain 5 of the cation-independent mannose 6-phosphate receptor, 8th Annual Conference of the Society-for-Glycobiology, Publisher: OXFORD UNIV PRESS INC, Pages: 869-869, ISSN: 0959-6658

Conference paper

Feizi T, Fazio F, Chai WC, Wong CHet al., 2003, Carbohydrate microarrays - a new set of technologies at the frontiers of glycomics, CURRENT OPINION IN STRUCTURAL BIOLOGY, Vol: 13, Pages: 637-645, ISSN: 0959-440X

Journal article

Chai W, Leteux C, Lawson AM, Stoll MSet al., 2003, On-line overpressure thin-layer chromatographic separation and electrospray mass spectrometric detection of glycolipids, Anal Chem, Vol: 75, Pages: 118-125, ISSN: 0003-2700

Journal article

Chai WG, Stoll MS, Galustian C, Lawson AM, Feizi Tet al., 2003, Neoglycolipid technology: Deciphering information content of glycome, RECOGNITION OF CARBOHYDRATES IN BIOLOGICAL SYSTEMS PT A: GENERAL PROCEDURES, Vol: 362, Pages: 160-195, ISSN: 0076-6879

Journal article

Feizi T, Fukui S, Galustian C, Lawson AM, Chai Wet al., 2002, Progress toward deciphering the information content in the glycome, Pages: 61-62

The results of researches being carried out on 'glycome', a group of oligosaccharide structures found in the organism, were presented. The neoglycoplipid (NGL) technology, was developed for lipid-linked oligosaccharides probes from glycoproteins for studying their interactions with carbohydrate recognizing proteins. The uses of NGL technology as the basis of a carbohydrate microarray system for generating large repertoires of immobilized oligosaccharides probes required for the detection of carbohydrate protein interactions, were also discussed. It was shown that these repertoires of NGLs are robust probes when presented on nitrocellulose membranes.

Conference paper

Martín MJ, Feizi T, Leteux C, Pavlovic D, Piskarev VE, Chai WGet al., 2002, An investigation of the interactions of E-selectin with fuco-oligosaccharides of the blood group family, GLYCOBIOLOGY, Vol: 12, Pages: 829-835, ISSN: 0959-6658

Journal article

Kogelberg H, Frenkiel TA, Birdsall B, Chai WG, Muskett FWet al., 2002, Binding of sucrose octasulphate to the C-type lectin-like domain of the recombinant natural killer cell receptor NKR-P1A observed by NMR spectroscopy, CHEMBIOCHEM, Vol: 3, Pages: 1072-1077, ISSN: 1439-4227

Journal article

Chai WG, Fukui S, Galustian C, Lawson AM, Feizi Tet al., 2002, Oligosaccharide microarrays for high-throughput detection and specificity - Assignments of carbohydrate-protein interactions, 7th Annual Conference of the Society-for-Glycobiology, Publisher: OXFORD UNIV PRESS INC, Pages: 675-676, ISSN: 0959-6658

Conference paper

Fukui S, Feizi T, Galustian C, Lawson AM, Chai WGet al., 2002, Oligosaccharide microarrays for high-throughput detection and specificity assignments of carbohydrate-protein interactions, NATURE BIOTECHNOLOGY, Vol: 20, Pages: 1011-1017, ISSN: 1087-0156

Journal article

Chai WG, Beeson JG, Lawson AM, 2002, The structural motif in chondroitin sulfate for adhesion of <i>Plasmodium falciparum</i>-infected erythrocytes comprises disaccharide units of 4-<i>O</i>-sulfated and non-sulfated <i>N</i>-acetylgalactosamine linked to glucuronic acid, JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 277, Pages: 22438-22446, ISSN: 0021-9258

Journal article

Chai W, Piskarev V, Lawson AM, 2002, Branching pattern and sequence analysis of underivatized oligosaccharides by combined MS/MS of singly and doubly charged molecular Ions in negative-ion electrospray mass spectrometry, J Am Soc Mass Spectrom, Vol: 13, Pages: 670-679, ISSN: 1044-0305

Journal article

Kogelberg H, Chai W, Feizi T, Lawson AMet al., 2001, NMR studies of mannitol-terminating oligosaccharides derived by reductive alkaline hydrolysis from brain glycoproteins, CARBOHYDRATE RESEARCH, Vol: 331, Pages: 393-401, ISSN: 0008-6215

Journal article

Leteux C, Chai WG, Nagai K, Herbert CG, Lawson AM, Feizi Tet al., 2001, 10E4 antigen of scrapie lesions contains an unusual nonsulfated heparan motif, JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 276, Pages: 12539-12545, ISSN: 0021-9258

Journal article

Chai W, Pisvarev V, Lawson AM, 2001, negative-ion electrospray mass spectrometry of neutral underivatized oligosaccharides, Anal Chem, Vol: 73, Pages: 651-657, ISSN: 0003-2700

Journal article

Osanai T, Chai W, Tajima Y, Shimoda Y, Sanai Y, Yuen CTet al., 2001, Expression of glycoconjugates bearing the Lewis X epitope during neural differentiation of P19 EC cells, FEBS Lett, Vol: 488, Pages: 23-28, ISSN: 0014-5793

Journal article

Chai W, Beeson JG, Kogelberg H, Brown GV, Lawson AMet al., 2001, Inhibition of adhesion of Plasmodium falciparum-infected erythrocytes by structurally defined hyaluronic acid dodecasaccharides, Infect Immun, Vol: 69, Pages: 420-425, ISSN: 0019-9567

Journal article

Leteux C, Chai WG, Loveless RW, Yuen CT, Uhlin-Hansen L, Combarnous Y, Jankovic M, Maric SC, Misulovin Z, Nussenzweig MC, Feizi Tet al., 2000, The cysteine-rich domain of the macrophage mannose receptor is a multispecific lectin that recognizes chondroitin sulfates A and B and sulfated oligosaccharides of blood group Lewis<SUP>a</SUP> and Lewis<SUP>x</SUP> types in addition to the sulfated <i>N</i>-glycans of lutropin, JOURNAL OF EXPERIMENTAL MEDICINE, Vol: 191, Pages: 1117-1126, ISSN: 0022-1007

Journal article

Stoll MS, Feizi T, Loveless RW, Chai WG, Lawson AM, Yuen CTet al., 2000, Fluorescent neoglycolipids - Improved probes for oligosaccharide ligand discovery, EUROPEAN JOURNAL OF BIOCHEMISTRY, Vol: 267, Pages: 1795-1804, ISSN: 0014-2956

Journal article

Beeson JG, Rogerson SJ, Cooke BM, Reeder JC, Chai WG, Lawson AM, Molyneux ME, Brown GVet al., 2000, Adhesion of <i>Plasmodium falciparum</i>-infected erythrocytes to hyaluronic acid in placental malaria, NATURE MEDICINE, Vol: 6, Pages: 86-90, ISSN: 1078-8956

Journal article

Chai WG, Yuen CT, Kogelberg H, Carruthers RA, Margolis RU, Feizi T, Lawson AMet al., 1999, High prevalence of 2-mono- and 2,6-di-substituted Manol-terminating sequences among O-glycans released from brain glycopeptides by reductive alkaline hydrolysis, EUROPEAN JOURNAL OF BIOCHEMISTRY, Vol: 263, Pages: 879-888, ISSN: 0014-2956

Journal article

Leteux C, Stoll MS, Childs RA, Chai W, Vorozhaikina M, Feizi Tet al., 1999, Influence of oligosaccharide presentation on the interactions of carbohydrate sequence-specific antibodies and the selectins - Observations with biotinylated oligosaccharides, JOURNAL OF IMMUNOLOGICAL METHODS, Vol: 227, Pages: 109-119, ISSN: 0022-1759

Journal article

Chai WG, Yuen CT, Feizi T, Lawson AMet al., 1999, Core-branching pattern and sequence analysis of mannitol-terminating oligosaccharides by neoglycolipid technology, ANALYTICAL BIOCHEMISTRY, Vol: 270, Pages: 314-322, ISSN: 0003-2697

Journal article

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