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@article{Jones:2018:10.21037/jtd.2018.03.18,
author = {Jones, SE and Barker, RE and Nolan, CM and Patel, S and Maddocks, M and Man, WDC},
doi = {10.21037/jtd.2018.03.18},
journal = {Journal of Thoracic Disease},
pages = {S1390--S1399},
title = {Pulmonary rehabilitation in patients with an acute exacerbation of chronic obstructive pulmonary disease.},
url = {http://dx.doi.org/10.21037/jtd.2018.03.18},
volume = {10},
year = {2018}
}

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TY  - JOUR
AB  - Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are one of the most common causes of emergency hospital admission and place great burden upon healthcare systems. Furthermore, AECOPD represent an important life event for patients, and are associated with significant reductions in physical activity, skeletal muscle function, exercise tolerance and health-related quality of life. Pulmonary rehabilitation, an intervention comprising supervised exercise-training and education, may counteract these negative consequences and target modifiable risk factors for hospital readmission. A recent Cochrane systematic review included 20 randomized controlled trials comparing pulmonary rehabilitation after exacerbation of COPD versus conventional care. Overall, the evidence supports moderate to large effects on health-related quality of life and exercise capacity. However, there is substantial heterogeneity across studies, and more recent studies have been more equivocal, including around hospital readmissions, particularly when rehabilitation is started in the inpatient setting. In this narrative review, we examine the rationale for pulmonary rehabilitation following AECOPD with a particular focus on skeletal muscle function, review the current evidence for pulmonary rehabilitation in the AECOPD setting, and identify areas that require future research, including the structure and nature of the intervention, improving uptake and adherence, and the role of alternative rehabilitation strategies for patients with AECOPD.
AU  - Jones,SE
AU  - Barker,RE
AU  - Nolan,CM
AU  - Patel,S
AU  - Maddocks,M
AU  - Man,WDC
DO  - 10.21037/jtd.2018.03.18
EP  - 1399
PY  - 2018///
SN  - 2072-1439
SP  - 1390
TI  - Pulmonary rehabilitation in patients with an acute exacerbation of chronic obstructive pulmonary disease.
T2  - Journal of Thoracic Disease
UR  - http://dx.doi.org/10.21037/jtd.2018.03.18
UR  - https://www.ncbi.nlm.nih.gov/pubmed/29928521
UR  - http://jtd.amegroups.com/article/view/19965/16303
VL  - 10
ER  -

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