Imperial College London
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DrWilliamMan

Faculty of Medicine, National Heart & Lung Institute

Reader in Respiratory Medicine
 
 
 
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+44 (0)1895 828 851w.man

 
 
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Harefield HospitalHarefield Hospital

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Summary

 

Publications

Citation

BibTex format

@article{Mesquita:2017:10.1177/1479972316687207,
author = {Mesquita, R and Spina, G and Pitta, F and Donaire-Gonzalez, D and Deering, BM and Patel, MS and Mitchell, KE and Alison, J and van, Gestel AJR and Zogg, S and Gagnon, P and Abascal-Bolado, B and Vagaggini, B and Garcia-Aymerich, J and Jenkins, SC and Romme, EAPM and Kon, SSC and Albert, PS and Waschki, B and Shrikrishna, D and Singh, SJ and Hopkinson, NS and Miedinger, D and Benzo, RP and Maltais, F and Paggiaro, P and McKeough, ZJ and Polkey, MI and Hill, K and Man, WD-C and Clarenbach, CF and Hernandes, NA and Savi, D and Wootton, S and Furlanetto, KC and Ng, LWC and Vaes, AW and Jenkins, C and Eastwood, PR and Jarreta, D and Kirsten, A and Brooks, D and Hillman, DR and Sant'Anna, T and Meijer, K and Durr, S and Rutten, EPA and Kohler, M and Probst, VS and Tal-Singer, R and Garcia, Gil E and den, Brinker AC and Leuppi, JD and Calverley, PMA and Smeenk, FWJM and Costello, RW and Gramm, M and Goldstein, R and Groenen, MTJ and Magnussen, H and Wouters, EFM and ZuWallack, RL and Amft, O },
doi = {10.1177/1479972316687207},
journal = {Chronic Respiratory Disease},
pages = {256--269},
title = {Physical activity patterns and clusters in 1001 patients with COPD},
url = {http://dx.doi.org/10.1177/1479972316687207},
volume = {14},
year = {2017}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - We described physical activity measures and hourly patterns in patients with chronic obstructive pulmonary disease (COPD) after stratification for generic and COPD-specific characteristics and, based on multiple physical activity measures, we identified clusters of patients. In total, 1001 patients with COPD (65% men; age, 67 years; forced expiratory volume in the first second [FEV1], 49% predicted) were studied cross-sectionally. Demographics, anthropometrics, lung function and clinical data were assessed. Daily physical activity measures and hourly patterns were analysed based on data from a multisensor armband. Principal component analysis (PCA) and cluster analysis were applied to physical activity measures to identify clusters. Age, body mass index (BMI), dyspnoea grade and ADO index (including age, dyspnoea and airflow obstruction) were associated with physical activity measures and hourly patterns. Five clusters were identified based on three PCA components, which accounted for 60% of variance of the data. Importantly, couch potatoes (i.e. the most inactive cluster) were characterised by higher BMI, lower FEV1, worse dyspnoea and higher ADO index compared to other clusters (p < 0.05 for all). Daily physical activity measures and hourly patterns are heterogeneous in COPD. Clusters of patients were identified solely based on physical activity data. These findings may be useful to develop interventions aiming to promote physical activity in COPD.
AU  - Mesquita,R
AU  - Spina,G
AU  - Pitta,F
AU  - Donaire-Gonzalez,D
AU  - Deering,BM
AU  - Patel,MS
AU  - Mitchell,KE
AU  - Alison,J
AU  - van,Gestel AJR
AU  - Zogg,S
AU  - Gagnon,P
AU  - Abascal-Bolado,B
AU  - Vagaggini,B
AU  - Garcia-Aymerich,J
AU  - Jenkins,SC
AU  - Romme,EAPM
AU  - Kon,SSC
AU  - Albert,PS
AU  - Waschki,B
AU  - Shrikrishna,D
AU  - Singh,SJ
AU  - Hopkinson,NS
AU  - Miedinger,D
AU  - Benzo,RP
AU  - Maltais,F
AU  - Paggiaro,P
AU  - McKeough,ZJ
AU  - Polkey,MI
AU  - Hill,K
AU  - Man,WD-C
AU  - Clarenbach,CF
AU  - Hernandes,NA
AU  - Savi,D
AU  - Wootton,S
AU  - Furlanetto,KC
AU  - Ng,LWC
AU  - Vaes,AW
AU  - Jenkins,C
AU  - Eastwood,PR
AU  - Jarreta,D
AU  - Kirsten,A
AU  - Brooks,D
AU  - Hillman,DR
AU  - Sant'Anna,T
AU  - Meijer,K
AU  - Durr,S
AU  - Rutten,EPA
AU  - Kohler,M
AU  - Probst,VS
AU  - Tal-Singer,R
AU  - Garcia,Gil E
AU  - den,Brinker AC
AU  - Leuppi,JD
AU  - Calverley,PMA
AU  - Smeenk,FWJM
AU  - Costello,RW
AU  - Gramm,M
AU  - Goldstein,R
AU  - Groenen,MTJ
AU  - Magnussen,H
AU  - Wouters,EFM
AU  - ZuWallack,RL
AU  - Amft,O
AU  - Watz,H
AU  - Spruit,MA
DO  - 10.1177/1479972316687207
EP  - 269
PY  - 2017///
SN  - 1479-9723
SP  - 256
TI  - Physical activity patterns and clusters in 1001 patients with COPD
T2  - Chronic Respiratory Disease
UR  - http://dx.doi.org/10.1177/1479972316687207
UR  - http://hdl.handle.net/10044/1/56906
VL  - 14
ER  -
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