Imperial College London

Prof. William Wisden F. Med. Sci.

Faculty of Natural SciencesDepartment of Life Sciences

Chair in Molecular Neuroscience



+44 (0)20 7594 9744w.wisden Website CV




401BSir Ernst Chain BuildingSouth Kensington Campus





Research interests and techniques

    AAV infected subicular neurons, Dr A. Zecharia
  • Neuroscience: molecular biology; transgenics, neuroanatomy, physiology, behaviour. 
  • Mechanisms of sleep
  • Hypothalamic function: the regulation of neurons which make histamine: the tuberomammillary nucleus and sleep regulation
  • other neuromodulators which regulate sleep



1986 BA,  Zoology - Natural Sciences, University of Cambridge
1989 PhD Molecular Neuroscience, University of Cambridge (with Stephen P. Hunt).

Posts held:

1990-1992 EMBO Long-term Fellowship, ZMBH, University of Heidelberg (with Peter H. Seeburg)
1993-2001 Group Leader, MRC LMB, Cambridge
2001-2005 Group Leader, IZN, University of Heidelberg
2005-2009 Professor & Chair of Neuroscience, Head of Neurobiology programme, Institute of Medical Sciences, University of Aberdeen

2009- Professor of Molecular Neuroscience



How to find us: click here for a map  - we are on the 4th floor  of the Sir Ernst Chain Building (marked "30" on the map)

Imperial College''s location in London:

 Royal Albert Hall - next to Imperial College

 Albert Hall - view from Imperial






Ye Z, Yu X, Houston CM, et al., 2017, Fast and Slow Inhibition in the Visual Thalamus Is Influenced by Allocating GABAA Receptors with Different γ Subunits., Front Cell Neurosci, Vol:11, ISSN:1662-5102

Ma S, Hangya B, Leonard CS, et al., 2017, Dual-transmitter systems regulating arousal, attention, learning and memory., Neurosci Biobehav Rev

Wisden W, Yu X, Franks NP, 2017, GABA Receptors and the Pharmacology of Sleep., Handb Exp Pharmacol, ISSN:0171-2004

Jager P, Ye Z, Yu X, et al., 2016, Tectal-derived interneurons contribute to phasic and tonic inhibition in the visual thalamus, Nature Communications, Vol:7, ISSN:2041-1723


Wisden W, Yu X, Ye Z, et al., 2016, Histamine and gamma-amino butyric acid co-transmission promotes arousal, 23rd Congress of the European-Sleep-Research-Society, WILEY-BLACKWELL, Pages:26-26, ISSN:0962-1105

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