Imperial College London


Faculty of MedicineDepartment of Medicine

Chair in Human Immunology



+44 (0)20 3315 6558x.xu




Mrs Julie James +44 (0)20 3315 8258




Chelsea and Westminster HospitalChelsea and Westminster Campus





Dr Xiao-Ning Xu qualified in Medicine from Capital Medical University (Beijing) in 1984 and obtained a PhD in Clinical Immunology in 1992 from Flinders Medical Centre (Australia) and became the fellow of the Royal College of Pathologists of Australasia (FRCPA) in 1999. He then joined the group of Prof Sir Andrew J. McMichael at Weatherall Institute of Molecular Medicine, University of Oxford.

For the last 10 years Xiao-Ning served as Medical Research Council (MRC) Senior Clinical Scientist, project leader, and tenured programme leader at MRC Human Immunology Unit, Oxford University, where he led research projects involving immune correlates of protection against emerging infectious diseases including HIV, SARS, and avian influenza. In 2010, he joined Novartis as the Head of Novartis Vaccines Research China, Novartis Vaccines & Diagnostics based in Shanghai, and is now the Chair professor in Human Immunology at the Imperial College of London based at Chelsea & Westminster Hospital.

Selected Publications

Journal Articles

Li CK-F, Rappuoli R, Xu X-N, 2013, Correlates of protection against influenza infection in humans - on the path to a universal vaccine?, Current Opinion in Immunology, Vol:25, ISSN:0952-7915, Pages:470-476

Bangs SC, Baban D, Cattan HJ, et al., 2009, Human CD4(+) Memory T Cells Are Preferential Targets for Bystander Activation and Apoptosis, Journal of Immunology, Vol:182, ISSN:0022-1767, Pages:1962-1971

Li CK-F, Wu H, Yan H, et al., 2008, T cell responses to whole SARS coronavirus in humans, Journal of Immunology, Vol:181, ISSN:0022-1767, Pages:5490-5500

Freundt EC, Yu L, Park E, et al., 2009, Molecular Determinants for Subcellular Localization of the Severe Acute Respiratory Syndrome Coronavirus Open Reading Frame 3b Protein, Journal of Virology, Vol:83, ISSN:0022-538X, Pages:6631-6640

Haig NA, Guan Z, Li D, et al., 2011, Identification of Self-lipids Presented by CD1c and CD1d Proteins, Journal of Biological Chemistry, Vol:286, ISSN:0021-9258, Pages:37692-37701

Li D, Wang L, Yu L, et al., 2009, Ig-Like Transcript 4 Inhibits Lipid Antigen Presentation through Direct CD1d Interaction, Journal of Immunology, Vol:182, ISSN:0022-1767, Pages:1033-1040

Wilkinson TM, Li CKF, Chui CSC, et al., 2012, Preexisting influenza-specific CD4(+) T cells correlate with disease protection against influenza challenge in humans, Nature Medicine, Vol:18, ISSN:1078-8956, Pages:274-280

Rajapaksa US, Li D, Peng Y-C, et al., 2012, HLA-B may be more protective against HIV-1 than HLA-A because it resists negative regulatory factor (Nef) mediated down-regulation, Proceedings of the National Academy of Sciences of the United States of America, Vol:109, ISSN:0027-8424, Pages:13353-13358

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