Imperial College London
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DrYiqunHan

Faculty of Medicine, School of Public Health

Research Associate
 
 
 
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Contact

 

yiqun.han

 
 
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Location

 

Sir Michael Uren HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Xu:2024:10.1016/j.envint.2024.108567,
author = {Xu, Y and Han, Y and Chen, W and Chatzidiakou, L and Yan, L and Krause, A and Li, Y and Zhang, H and Wang, T and Xue, T and Chan, Q and Barratt, B and Jones, RL and Liu, J and Wu, Y and Zhao, M and Zhang, J and Kelly, FJ and Zhu, T},
doi = {10.1016/j.envint.2024.108567},
journal = {Environ Int},
title = {Susceptibility of hypertensive individuals to acute blood pressure increases in response to personal-level environmental temperature decrease.},
url = {http://dx.doi.org/10.1016/j.envint.2024.108567},
volume = {185},
year = {2024}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BACKGROUND: Environmental temperature is negatively associated with blood pressure (BP), and hypertension may exacerbate this association. The aim of this study is to investigate whether hypertensive individuals are more susceptible to acute BP increases following temperature decrease than non-hypertensive individuals. METHODS: The study panel consisted of 126 hypertensive and 125 non-hypertensive (n = 251) elderly participants who completed 940 clinical visits during the winter of 2016 and summer of 2017 in Beijing, China. Personal-level environmental temperature (PET) was continuously monitored for each participant with a portable sensor platform. We associated systolic BP (SBP) and diastolic BP (DBP) with the average PET over 24 h before clinical visits using linear mixed-effects models and explored hourly lag patterns for the associations using distributed lag models. RESULTS: We found that per 1 °C decrease in PET, hypertensive individuals showed an average (95 % confidence interval) increase of 0.96 (0.72, 1.19) and 0.28 (0.13, 0.42) mmHg for SBP and DBP, respectively; and non-hypertensive participants showed significantly smaller increases of 0.28 (0.03, 0.53) mmHg SBP and 0.14 (-0.01, 0.30) mmHg DBP. A lag pattern analysis showed that for hypertensive individuals, the increases in SBP and DBP were greatest following lag 1 h PET decrease and gradually attenuated up to lag 10 h exposure. No significant BP change was observed in non-hypertensive individuals associated with lag 1-24 h PET exposure. The enhanced increase in PET-associated BP in hypertensive participants (i.e., susceptibility) was more significant in winter than in summer. CONCLUSIONS: We found that a decrease in environmental temperature was associated with acute BP increases and these associations diminished over time, disappearing after approximately 10 hours. This implies that any intervention measures to prevent BP increases due to temperature drop
AU  - Xu,Y
AU  - Han,Y
AU  - Chen,W
AU  - Chatzidiakou,L
AU  - Yan,L
AU  - Krause,A
AU  - Li,Y
AU  - Zhang,H
AU  - Wang,T
AU  - Xue,T
AU  - Chan,Q
AU  - Barratt,B
AU  - Jones,RL
AU  - Liu,J
AU  - Wu,Y
AU  - Zhao,M
AU  - Zhang,J
AU  - Kelly,FJ
AU  - Zhu,T
DO  - 10.1016/j.envint.2024.108567
PY  - 2024///
TI  - Susceptibility of hypertensive individuals to acute blood pressure increases in response to personal-level environmental temperature decrease.
T2  - Environ Int
UR  - http://dx.doi.org/10.1016/j.envint.2024.108567
UR  - https://www.ncbi.nlm.nih.gov/pubmed/38460242
VL  - 185
ER  -
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