Imperial College London
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DR YUTONG SAMUEL CAI

Faculty of Medicine, School of Public Health

Honorary Research Fellow
 
 
 
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Contact

 

yutong.cai

 
 
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Location

 

155Wright Fleming WingSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Liang:2019:10.1016/S2542-5196(19)30085-3,
author = {Liang, L and Cai, Y and Barratt, B and Lyu, B and Chan, Q and Hansell, AL and Xie, W and Zhang, D and Kelly, FJ and Tong, Z},
doi = {10.1016/S2542-5196(19)30085-3},
journal = {Lancet Planet Health},
pages = {e270--e279},
title = {Associations between daily air quality and hospitalisations for acute exacerbation of chronic obstructive pulmonary disease in Beijing, 2013-17: an ecological analysis},
url = {http://dx.doi.org/10.1016/S2542-5196(19)30085-3},
volume = {3},
year = {2019}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BACKGROUND: Air pollution in Beijing has been improving through implementation of the Air Pollution Prevention and Control Action Plan (2013-17), but its implications for respiratory morbidity have not been directly investigated. We aimed to assess the potential effects of air-quality improvements on respiratory health by investigating the number of cases of acute exacerbations of chronic obstructive pulmonary disease (COPD) advanced by air pollution each year. METHODS: Daily city-wide concentrations of PM10, PM2.5, PMcoarse (particulate matter >2.5-10 mum diameter), nitrogen dioxide (NO2), sulphur dioxide (SO2), carbon monoxide (CO), and ozone (O3) in 2013-17 were averaged from 35 monitoring stations across Beijing. A generalised additive Poisson time-series model was applied to estimate the relative risks (RRs) and 95% CIs for hospitalisation for acute exacerbation of COPD associated with pollutant concentrations. FINDINGS: From Jan 18, 2013, to Dec 31, 2017, 161 613 hospitalisations for acute exacerbation of COPD were recorded. Mean ambient concentrations of SO2 decreased by 68% and PM2.5 decreased by 33% over this 5-year period. For each IQR increase in pollutant concentration, RRs for same-day hospitalisation for acute exacerbation of COPD were 1.029 (95% CI 1.023-1.035) for PM10, 1.028 (1.021-1.034) for PM2.5, 1.018 (1.013-1.022) for PMcoarse, 1.036 (1.028-1.044) for NO2, 1.019 (1.013-1.024) for SO2, 1.024 (1.018-1.029) for CO, and 1.027 (1.010-1.044) for O3 in the warm season (May to October). Women and patients aged 65 years or older were more susceptible to the effects of these pollutants on hospitalisation risk than were men and patients younger than 65 years. In 2013, there were 12 679 acute exacerbations of COPD cases that were advanced by PM2.5 pollution above the expected number of cases if daily PM2.5 concentrations had not exceeded the WHO target (25 mug/m(3)), whereas the respective figure in 2017 was 7377 cases. INTERPRETATION: Despite improveme
AU  - Liang,L
AU  - Cai,Y
AU  - Barratt,B
AU  - Lyu,B
AU  - Chan,Q
AU  - Hansell,AL
AU  - Xie,W
AU  - Zhang,D
AU  - Kelly,FJ
AU  - Tong,Z
DO  - 10.1016/S2542-5196(19)30085-3
EP  - 279
PY  - 2019///
SN  - 2542-5196
SP  - 270
TI  - Associations between daily air quality and hospitalisations for acute exacerbation of chronic obstructive pulmonary disease in Beijing, 2013-17: an ecological analysis
T2  - Lancet Planet Health
UR  - http://dx.doi.org/10.1016/S2542-5196(19)30085-3
UR  - https://www.ncbi.nlm.nih.gov/pubmed/31229002
UR  - http://hdl.handle.net/10044/1/70306
VL  - 3
ER  -
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