Imperial College London

Dr Melody Zhifang Ni

Faculty of MedicineDepartment of Surgery & Cancer

Research Fellow



+44 (0)20 3312




Queen Elizabeth the Queen Mother Wing (QEQM)St Mary's Campus






Melody is a methodologist and decision scientist. Her research focuses on improving decision making in the context of surgical quality, patient safety and innovation. 

Melody's first project at Imperial examined safety of  various bedside methods for siting nasogastric feeding tubes. She used Bayesian networks to synthesise evidence  and visualised the dynamics between test results and feeding safety. Collaborating with a Scottish SME  Ingenza, we have completed a 10-site diagnostic performance study which demonstrated superior sensitivity of a new generation of pH strips against standard pH strips.  

Melody's work on surgical quality started from the National Training Programme in Laparoscopic Colorectal Cancer Surgeries, or Lapco, which trained 144 consultant colorectal surgeons in 11 national training centres. As a member of the education team, we developed tailor-made assessment forms and processes which we found to have predictive validity of clinical outcomes of Lapco delegates three years post-training. Lapco is considered best practice of training at the post-graduate (consultant) level. 

Since 2014, Melody has been a senior methodologist within the NIHR-London In Vitro Diagnostics Co-operative (formerly NIHR Diagnostic Evidence Cooperative). Within London IVD, we are working on developing efficient ways of evidence generation in order to enable better translation of exciting new ideas into products with tangible benefits. 

Selected Publications

Journal Articles

Huddy JR, Ni M, Misra S, et al., 2019, Development of the Point-of-Care Key Evidence Tool (POCKET): a checklist for multi-dimensional evidence generation in point-of-care tests, Clinical Chemistry and Laboratory Medicine, Vol:57, ISSN:1434-6621, Pages:845-855

Subbe CP, Bannard-Smith J, Bunch J, et al., 2019, Quality metrics for the evaluation of Rapid Response Systems: Proceedings from the third international consensus conference on Rapid Response Systems., Resuscitation, Vol:141, Pages:1-12

Borsci S, Uchegbu I, Buckle P, et al., 2017, Designing medical technology for resilience: Integrating health economics and human factors approaches, Expert Review of Medical Devices, Vol:15, ISSN:1743-4440, Pages:15-26

Ni MZ, Huddy JR, Priest OH, et al., 2017, Selecting pH cut-offs for the safe verification of nasogastric feeding tube placement: a decision analytical modelling approach., Bmj Open, Vol:7, ISSN:2044-6055

Markar S, Mackenzie H, Ni Z, et al., 2017, The influence of procedural volume and proficiency gain on mortality from upper GI endoscopic mucosal resection, Gut, Vol:67, ISSN:1468-3288, Pages:79-85

Acharya A, Markar SR, Matar M, et al., 2016, Use of Tumor Markers in Gastrointestinal Cancers: Surgeon Perceptions and Cost-Benefit Trade-Off Analysis, Annals of Surgical Oncology, Vol:24, ISSN:1068-9265, Pages:1165-1173

Markar SR, Mackenzie H, Ni M, et al., 2016, The influence of procedural volume and proficiency gain on mortality from upper GI endoscopic mucosal resection, Gut, ISSN:0017-5749

Mamidanna R, Ni Z, Anderson O, et al., 2016, Surgeon Volume and Cancer Esophagectomy, Gastrectomy, and Pancreatectomy: A Population-based Study in England, Annals of Surgery, Vol:263, ISSN:1528-1140, Pages:727-732

Miskovic D, Ni M, Wyles SM, et al., 2013, Is Competency Assessment at the Specialist Level Achievable? A Study for the National Training Programme in Laparoscopic Colorectal Surgery in England, Annals of Surgery, Vol:257, ISSN:0003-4932, Pages:476-482

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