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Imperial College London has international reputation for research in perinatal neurology and brain imaging, spanning over several decades. We were the first in the world to have a dedicated in-unit neonatal 3 Telsa MRI scanner.

We lead one of the largest clinical research programs in neonatal encephalopathy in the world. Neonatal encephalopathy, or brain injury related to 'birth asphyxia' is a devastating condition due to a presumed lack of oxygen and blood flow to the fetal brain, possibly around the time of birth. Pioneering research undertaken in the unit, along with many other researchers and collaborators in the UK and worldwide led to the establishment of brain cooling as the first effective therapy for neonatal encephalopathy. However, despite cooling therapy, almost half of the babies born with neonatal encephalopathy will have adverse outcomes.

Our current work is focussed on developing effective disease stratification tools for developing personalised neuroprotection in neonatal encephalopathy and evaluating these using quantitative MR spectroscopy biomarkers in a multi-country setting.


HELIX Trial Video

 

 

 

 

 

 

 

PREVENT Study Web Link

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Research team

Mythilli Babu

Mythilli Babu

Mythilli Babu
Research Nurse (HELIX)

Ms Constance Burgod

Ms Constance Burgod

Ms Constance Burgod
MRes student

Dr Gaurav Atreja

Gaurav Atreja

Dr Gaurav Atreja
Consultant Neonatologist

Dr Vaisakh Krishnan

Vaisakh

Dr Vaisakh Krishnan
Clinical Research Associate (PhD student)

Dr Vijay Kumar

Dr Vijay Kumar

Dr Vijay Kumar
Clinical Research Associate (PhD student)

Josephine Mendoza

Josephine Mendoza

Josephine Mendoza
Neonatal Neurology Research Nurse

Dr Chris Merin Varghese

Dr Chris Merin Varghese

Dr Chris Merin Varghese
Project manager (PREVENT)

Ms Pallavi Muraleedharan

Ms Pallavi Muraleedhran

Ms Pallavi Muraleedharan
NIHR SPARK Fellow and Research Associate (PhD Student)

Indiramma Prabhu

Indiramma Prabhu

Indiramma Prabhu
Research Nurse (HELIX)

Dr Vijayakumar Shivamurthappa,

Shivamurthappa, Vijayakumar

Dr Vijayakumar Shivamurthappa,
Consultant Neonatologist

Dr Deepika Shukla

Deepika Shukla

Dr Deepika Shukla
Senior MR Physicist

Dr Ravi Swamy

Ravi Swamy

Dr Ravi Swamy
Consultant Neonatologist and Director of Perinatal Trials Unit Foundation, Bangalore