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FILM - Facility for Imaging by Light Microscopy

Publications arising from projects performed in the FILM

NOTE: This page is work in progress, it only contains some selected publications; because of the notorious difficulty to track pages coming out of the facility, we are currently trialling an automated system, which will hopefully be up and running soon.

Selected publications

=> A complete publication list can be downloaded: <FILM Publication List> (pdf)

Toepfer C, Caorsi V, Kampourakis T, Sikkel MB, West TG, Leung MC, Al-Saud SA, Macleod KT, Lyon AR, Marston SB, Sellers JR, Ferenczi MA: "Myosin Regulatory Light Chain (RLC) Phosphorylation Change as a Modulator of Cardiac Muscle Contraction in Disease". J Biol Chem 288: 13446-13454 (2013)

Taylor HB, Liepe J, Barthen C, Bugeon L, Huvet M, Kirk PD, Brown SB, Lamb JR, Stumpf MP, Dallman MJ: "P38 and JNK have opposing effects on persistence of in vivo leukocyte migration in zebrafish". Immunol Cell Biol 91: 60-69 (2013)

Rudnicka D, Oszmiana A, Finch DK, Strickland I, Schofield DJ, Lowe DC, Sleeman MA, Davis DM: "Rituximab causes a polarisation of B cells which augments its therapeutic function in NK cell-mediated antibody-dependent cellular cytotoxicity". Blood(2013)

Lombardo F, Ghani Y, Kafatos FC, Christophides GK: "Comprehensive genetic dissection of the hemocyte immune response in the malaria mosquito Anopheles gambiae". PLoS Pathog 9: e1003145 (2013)

Caorsi V, Toepfer C, Sikkel MB, Lyon AR, MacLeod K, Ferenczi MA: "Non-linear optical microscopy sheds light on cardiovascular disease". PLoS One 8: e56136 (2013)

Zhu J, Bandi V, Qiu S, Figueroa DJ, Evans JF, Barnes N, Guntupalli KK, Jeffery PK: "Cysteinyl Leukotriene 1 Receptor Expression Associated With Bronchial Inflammation in Severe Exacerbations of COPD". Chest 142: 347-357 (2012)

Zecharia AY, Yu X, Gotz T, Ye Z, Carr DR, Wulff P, Bettler B, Vyssotski AL, Brickley SG, Franks NP, Wisden W: "GABAergic inhibition of histaminergic neurons regulates active waking but not the sleep-wake switch or propofol-induced loss of consciousness". J Neurosci 32: 13062-13075 (2012)

Sprong H, Tijsse-Klasen E, Langelaar M, De Bruin A, Fonville M, Gassner F, Takken W, Van Wieren S, Nijhof A, Jongejan F, Maassen CB, Scholte EJ, Hovius JW, Emil Hovius K, Spitalska E, Van Duynhoven YT: "Prevalence of Coxiella burnetii in ticks after a large outbreak of Q fever". Zoonoses Public Health 59: 69-75 (2012)

Shcherbakova DM, Subach OM, Verkhusha VV: "Red Fluorescent Proteins: Advanced Imaging Applications and Future Design". Angew Chem Int Ed Engl(2012)

Russell CA, Fonville JM, Brown AE, Burke DF, Smith DL, James SL, Herfst S, van Boheemen S, Linster M, Schrauwen EJ, Katzelnick L, Mosterin A, Kuiken T, Maher E, Neumann G, Osterhaus AD, Kawaoka Y, Fouchier RA, Smith DJ: "The potential for respiratory droplet-transmissible A/H5N1 influenza virus to evolve in a mammalian host". Science 336: 1541-1547 (2012)

Pfenniger A, Wong C, Sutter E, Cuhlmann S, Dunoyer-Geindre S, Mach F, Horrevoets AJ, Evans PC, Krams R, Kwak BR: "Shear stress modulates the expression of the atheroprotective protein Cx37 in endothelial cells". J Mol Cell Cardiol 53: 299-309 (2012)

Nola S, Erasmus JC, Braga VM: "Quantitative and robust assay to measure cell-cell contact assembly and maintenance". Methods Mol Biol 827: 143-155 (2012)

Maher AD, Fonville JM, Coen M, Lindon JC, Rae CD, Nicholson JK: "Statistical total correlation spectroscopy scaling for enhancement of metabolic information recovery in biological NMR spectra". Anal Chem 84: 1083-1091 (2012)

Liepe J, Taylor H, Barnes CP, Huvet M, Bugeon L, Thorne T, Lamb JR, Dallman MJ, Stumpf MP: "Calibrating spatio-temporal models of leukocyte dynamics against in vivo live-imaging data using approximate Bayesian computation". Integr Biol (Camb) 4: 335-345 (2012)

Kirchmaier BC, Poon KL, Schwerte T, Huisken J, Winkler C, Jungblut B, Stainier DY, Brand T: "The Popeye domain containing 2 (popdc2) gene in zebrafish is required for heart and skeletal muscle development". Dev Biol 363: 438-450 (2012)

Kalaji R, Wheeler AP, Erasmus JC, Lee SY, Endres RG, Cramer LP, Braga VM: "ROCK1 and ROCK2 regulate epithelial polarisation and geometric cell shape". Biol Cell 104: 435-451 (2012)

Jahfari S, Fonville M, Hengeveld P, Reusken C, Scholte EJ, Takken W, Heyman P, Medlock J, Heylen D, Kleve J, Sprong H: "Prevalence of Neoehrlichia mikurensis in ticks and rodents from North-west Europe". Parasit Vectors 5: 74 (2012)

Ibrahim M, Kukadia P, Siedlecka U, Cartledge JE, Navaratnarajah M, Tokar S, Van Doorn C, Tsang VT, Gorelik J, Yacoub MH, Terracciano CM: "Cardiomyocyte Ca2+ handling and structure is regulated by degree and duration of mechanical load variation". J Cell Mol Med 16: 2910-2918 (2012)

Heylen D, Tijsse E, Fonville M, Matthysen E, Sprong H: "Transmission dynamics of Borrelia burgdorferi s.l. in a bird tick community". Environ Microbiol(2012)

Gruda R, Brown AC, Grabovsky V, Mizrahi S, Gur C, Feigelson SW, Achdout H, Bar-On Y, Alon R, Aker M, Davis DM, Mandelboim O: "Loss of kindlin-3 alters the threshold for NK cell activation in human leukocyte adhesion deficiency-III". Blood 120: 3915-3924 (2012)

Fonville JM, Swart M, Vokacova Z, Sychrovsky V, Sponer JE, Sponer J, Hilbers CW, Bickelhaupt FM, Wijmenga SS: "Chemical shifts in nucleic acids studied by density functional theory calculations and comparison with experiment". Chemistry 18: 12372-12387 (2012)

Fonville JM, Carter CL, Pizarro L, Steven RT, Palmer AD, Griffiths RL, Lalor PF, Lindon JC, Nicholson JK, Holmes E, Bunch J: "Hyperspectral visualization of mass spectrometry imaging data". Anal Chem(2012)

Fonville JM, Carter C, Cloarec O, Nicholson JK, Lindon JC, Bunch J, Holmes E: "Robust data processing and normalization strategy for MALDI mass spectrometric imaging". Anal Chem 84: 1310-1319 (2012)

Ferguson LS, Wulfert F, Wolstenholme R, Fonville JM, Clench MR, Carolan VA, Francese S: "Direct detection of peptides and small proteins in fingermarks and determination of sex by MALDI mass spectrometry profiling". Analyst 137: 4686-4692 (2012)

Elbediwy A, Zihni C, Terry SJ, Clark P, Matter K, Balda MS: "Epithelial junction formation requires confinement of Cdc42 activity by a novel SH3BP1 complex". J Cell Biol 198: 677-693 (2012)

Byrne SM, Aucher A, Alyahya S, Elder M, Olson ST, Davis DM, Ashton-Rickardt PG: "Cathepsin B controls the persistence of memory CD8+ T lymphocytes". J Immunol 189: 1133-1143 (2012)

Brown AC, Dobbie IM, Alakoskela JM, Davis I, Davis DM: "Super-resolution imaging of remodeled synaptic actin reveals different synergies between NK cell receptors and integrins". Blood 120: 3729-3740 (2012)

Wormann ME, Corrigan RM, Simpson PJ, Matthews SJ, Grundling A: "Enzymatic activities and functional interdependencies of Bacillus subtilis lipoteichoic acid synthesis enzymes". Mol Microbiol 79: 566-583 (2011)

Ushakov DS, Caorsi V, Ibanez-Garcia D, Manning HB, Konitsiotis AD, West TG, Dunsby C, French PM, Ferenczi MA: "Response of rigor cross-bridges to stretch detected by fluorescence lifetime imaging microscopy of myosin essential light chain in skeletal muscle fibers". J Biol Chem 286: 842-850 (2011)

Ushakov DS, Caorsi V, Ibanez-Garcia D, Manning HB, Konitsiotis AD, West TG, Dunsby C, French PM, Ferenczi MA: "Response of rigor cross-bridges to stretch detected by fluorescence lifetime imaging microscopy of myosin essential light chain in skeletal muscle fibers". J Biol Chem 286: 842-850 (2011)

Sowinski S, Alakoskela JM, Jolly C, Davis DM: "Optimized methods for imaging membrane nanotubes between T cells and trafficking of HIV-1". Methods 53: 27-33 (2011)

Kaplan A, Kotzer S, Almeida CR, Kohen R, Halpert G, Salmon-Divon M, Kohler K, Hoglund P, Davis DM, Mehr R: "Simulations of the NK cell immune synapse rev eal that activation thresholds can be established by inhibitory receptors acting locally". J Immunol 187: 760-773 (2011)

Engl C, Beek AT, Bekker M, de Mattos JT, Jovanovic G, Buck M: "Dissipation of proton motive force is not sufficient to induce the phage shock protein response in Escherichia coli". Curr Microbiol 62: 1374-1385 (2011)

Eifan AO, Shamji MH, Durham SR: "Long-term clinical and immunological effects of allergen immunotherapy". Curr Opin Allergy Clin Immunol 11: 586-593 (2011)

Corrigan RM, Abbott JC, Burhenne H, Kaever V, Grundling A: "c-di-AMP is a new second messenger in Staphylococcus aureus with a role in controlling cell size and envelope stress". PLoS Pathog 7: e1002217 (2011)

Caorsi V, Ushakov DS, West TG, Setta-Kaffetzi N, Ferenczi MA: "FRET characterisation for cross-bridge dynamics in single-skinned rigor muscle fibres". Eur Biophys J 40: 13-27 (2011)

Burroughs NJ, Kohler K, Miloserdov V, Dustin ML, van der Merwe PA, Davis DM: "Boltzmann energy-based image analysis demonstrates that extracellular domain size differences explain protein segregation at immune synapses". PLoS Comput Biol 7: e1002076 (2011)

Brown AC, Oddos S, Dobbie IM, Alakoskela JM, Parton RM, Eissmann P, Neil MA, Dunsby C, French PM, Davis I, Davis DM: "Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy". PLoS Biol 9: e1001152 (2011)

Alakoskela JM, Koner AL, Rudnicka D, Kohler K, Howarth M, Davis DM: "Mechanisms for size-dependent protein segregation at immune synapses assessed with molecular rulers". Biophys J 100: 2865-2874 (2011)

Yang J, Kohler K, Davis DM, Burroughs NJ: "An improved strip FRAP method for estimating diffusion coefficients: correcting for the degree of photobleaching". J Microsc 238: 240-253 (2010)

Taylor AE, Finney-Hayward TK, Quint JK, Thomas CM, Tudhope SJ, Wedzicha JA, Barnes PJ, Donnelly LE: "Defective macrophage phagocytosis of bacteria in COPD". Eur Respir J 35: 1039-1047 (2010)

Taylor AE, Finney-Hayward TK, Quint JK, Thomas CM, Tudhope SJ, Wedzicha JA, Barnes PJ, Donnelly LE: "Defective macrophage phagocytosis of bacteria in COPD". Eur Respir J 35: 1039-1047 (2010)

Stamati I, Kuimova MK, Lion M, Yahioglu G, Phillips D, Deonarain MP: "Novel photosensitisers derived from pyropheophorbide-a: uptake by cells and photodynamic efficiency in vitro". Photochem Photobiol Sci 9: 1033-1041 (2010)

Purbhoo MA, Liu H, Oddos S, Owen DM, Neil MA, Pageon SV, French PM, Rudd CE, Davis DM: "Dynamics of subsynaptic vesicles and surface microclusters at the immunological synapse". Sci Signal 3: ra36 (2010)

Lei Y, Overby DR, Read AT, Stamer WD, Ethier CR: "A new method for selection of angular aqueous plexus cells from porcine eyes: a model for Schlemm's canal endothelium". Invest Ophthalmol Vis Sci 51: 5744-5750 (2010)

Ibanez-Garcia D, Requejo-Isidro J, Webb MR, West TG, French P, Ferenczi MA: "Fluorescence lifetime imaging reveals that the environment of the ATP binding site of myosin in muscle senses force". Biophys J 99: 2163-2169 (2010)

Hughes S, Jenkins V, Dar MJ, Engelman A, Cherepanov P: "Transcriptional co-activator LEDGF interacts with Cdc7-activator of S-phase kinase (ASK) and stimulates its enzymatic activity". J Biol Chem 285: 541-554 (2010)

Green JA, Elkington PT, Pennington CJ, Roncaroli F, Dholakia S, Moores RC, Bullen A, Porter JC, Agranoff D, Edwards DR, Friedland JS: "Mycobacterium tuberculosis upregulates microglial matrix metalloproteinase-1 and -3 expression and secretion via NF-kappaB- and Activator Protein-1-dependent monocyte networks". J Immunol 184: 6492-6503 (2010)

Frasa MA, Maximiano FC, Smolarczyk K, Francis RE, Betson ME, Lozano E, Goldenring J, Seabra MC, Rak A, Ahmadian MR, Braga VM: "Armus is a Rac1 effector that inactivates Rab7 and regulates E-cadherin degradation". Curr Biol 20: 198-208 (2010)

Chaudhury H, Zakkar M, Boyle J, Cuhlmann S, van der Heiden K, Luong le A, Davis J, Platt A, Mason JC, Krams R, Haskard DO, Clark AR, Evans PC: "c-Jun N-terminal kinase primes endothelial cells at atheroprone sites for apoptosis". Arterioscler Thromb Vasc Biol 30: 546-553 (2010)

Carlucci F, Fossati-Jimack L, Dumitriu IE, Heidari Y, Walport MJ, Szajna M, Baruah P, Garden OA, Cook HT, Botto M: "Identification and characterization of a lupus suppressor 129 locus on chromosome 3". J Immunol 184: 6256-6265 (2010)

Ansari AW, Temblay JN, Alyahya SH, Ashton-Rickardt PG: "Serine protease inhibitor 6 protects iNKT cells from self-inflicted damage". J Immunol 185: 877-883 (2010)

Zakkar M, Van der Heiden K, Luong le A, Chaudhury H, Cuhlmann S, Hamdulay SS, Krams R, Edirisinghe I, Rahman I, Carlsen H, Haskard DO, Mason JC, Evans PC: "Activation of Nrf2 in endothelial cells protects arteries from exhibiting a proinflammatory state". Arterioscler Thromb Vasc Biol 29: 1851-1857 (2009)

van Zon JS, Tzircotis G, Caron E, Howard M: "A mechanical bottleneck explains the variation in cup growth during FcgammaR phagocytosis". Mol Syst Biol 5: 298 (2009)

Russell RA, Adams NM, Stephens DA, Batty E, Jensen K, Freemont PS: "Segmentation of fluorescence microscopy images for quantitative analysis of cell nuclear architecture". Biophys J 96: 3379-3389 (2009)

Russell RA, Adams NM, Stephens DA, Batty E, Jensen K, Freemont PS: "Segmentation of fluorescence microscopy images for quantitative analysis of cell nuclear architecture". Biophys J 96: 3379-3389 (2009)

Rogers DW, Baldini F, Battaglia F, Panico M, Dell A, Morris HR, Catteruccia F: "Transglutaminase-mediated semen coagulation controls sperm storage in the malaria mosquito". PLoS Biol 7: e1000272 (2009)

Povelones M, Waterhouse RM, Kafatos FC, Christophides GK: "Leucine-rich repeat protein complex activates mosquito complement in defense against Plasmodium parasites". Science 324: 258-261 (2009)

Papathanos PA, Windbichler N, Menichelli M, Burt A, Crisanti A: "The vasa regulatory region mediates germline expression and maternal transmission of proteins in the malaria mosquito Anopheles gambiae: a versatile tool for genetic control strategies". BMC Mol Biol 10: 65 (2009)

Nicolson TJ, Bellomo EA, Wijesekara N, Loder MK, Baldwin JM, Gyulkhandanyan AV, Koshkin V, Tarasov AI, Carzaniga R, Kronenberger K, Taneja TK, da Silva Xavier G, Libert S, Froguel P, Scharfmann R, Stetsyuk V, Ravassard P, Parker H, Gribble FM, Reimann F, Sladek R, Hughes SJ, Johnson PR, Masseboeuf M, Burcelin R, Baldwin SA, Liu M, Lara-Lemus R, Arvan P, Schuit FC, Wheeler MB, Chimienti F, Rutter GA: "Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants". Diabetes 58: 2070-2083 (2009)

Munkonge FM, Amin V, Hyde SC, Green AM, Pringle IA, Gill DR, Smith JW, Hooley RP, Xenariou S, Ward MA, Leeds N, Leung KY, Chan M, Hillery E, Geddes DM, Griesenbach U, Postel EH, Dean DA, Dunn MJ, Alton EW: "Identification and functional characterization of cytoplasmic determinants of plasmid DNA nuclear import". J Biol Chem 284: 26978-26987 (2009)

Liebig T, Erasmus J, Kalaji R, Davies D, Loirand G, Ridley A, Braga VM: "RhoE Is required for keratinocyte differentiation and stratification". Mol Biol Cell 20: 452-463 (2009)

Lal K, Prieto JH, Bromley E, Sanderson SJ, Yates JR, 3rd, Wastling JM, Tomley FM, Sinden RE: "Characterisation of Plasmodium invasive organelles; an ookinete microneme proteome". Proteomics 9: 1142-1151 (2009)

Hume AN, Buttgereit J, Al-Awadhi AM, Al-Suwaidi SS, John A, Bader M, Seabra MC, Al-Gazali L, Ali BR: "Defective cellular trafficking of missense NPR-B mutants is the major mechanism underlying acromesomelic dysplasia-type Maroteaux". Hum Mol Genet 18: 267-277 (2009)

Gregory-Evans K, Chang F, Hodges MD, Gregory-Evans CY: "Ex vivo gene therapy using intravitreal injection of GDNF-secreting mouse embry onic stem cells in a rat model of retinal degeneration". Mol Vis 15: 962-973 (2009)

Engl C, Jovanovic G, Lloyd LJ, Murray H, Spitaler M , Ying L, Errington J, Buck M: "In vivo localizations of membrane stress controllers PspA and PspG in Escherichia coli". Mol Microbiol(2009)

Culley FJ, Johnson M, Evans JH, Kumar S, Crilly R, Casasbuenas J, Schnyder T, Mehrabi M, Deonarain MP, Ushakov DS, Braud V, Roth G, Brock R, Kohler K, Davis DM: "Natural killer cell signal integration balances synapse symmetry and migration". PLoS Biol 7: e1000159 (2009)

Bushell ES, Ecker A, Schlegelmilch T, Goulding D, Dougan G, Sinden RE, Christophides GK, Kafatos FC, Vlachou D: "Paternal effect of the nuclear formin-like protein MISFIT on Plasmodium development in the mosquito vector". PLoS Pathog 5: e1000539 (2009)

Windbichler N, Papathanos PA, Crisanti A: "Targeting the X chromosome during spermatogenesis induces Y chromosome transmission ratio distortion and early dominant embryo lethality in Anopheles gambiae". PLoS Genet 4: e1000291 (2008)

Tarasov AI, Nicolson TJ, Riveline JP, Taneja TK, Baldwin SA, Baldwin JM, Charpentier G, Gautier JF, Froguel P, Vaxillaire M, Rutter GA: "A rare mutation in ABCC8/SUR1 leading to altered ATP-sensitive K+ channel activity and beta-cell glucose sensing is associated with type 2 diabetes in adults". Diabetes 57: 1595-1604 (2008)

Sowinski S, Jolly C, Berninghausen O, Purbhoo MA, Chauveau A, Kohler K, Oddos S, Eissmann P, Brodsky FM, Hopkins C, Onfelt B, Sattentau Q, Davis DM: "Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission". Nat Cell Biol(2008)

Siti-Ismail N, Bishop AE, Polak JM, Mantalaris A: "The benefit of human embryonic stem cell encapsulation for prolonged feeder-free maintenance". Biomaterials 29: 3946-3952 (2008)

Moosajee M, Gregory-Evans K, Ellis CD, Seabra MC, Gregory-Evans CY: "Translational bypass of nonsense mutations in zebrafish rep1, pax2.1 and lamb1 highlights a viable therapeutic option for untreatable genetic eye disease". Hum Mol Genet 17: 3987-4000 (2008)

Jones S, Tucker KL, Sage T, Kaiser WJ, Barrett NE, Lowry PJ, Zimmer A, Hunt SP, Emerson M, Gibbins JM: "Peripheral tachykinins and the neurokinin receptor NK1 are required for platelet thrombus formation". Blood 111: 605-612 (2008)

Gorelik J, Ali NN, Sheikh Abdul Kadir SH, Lab M, Stojkovic P, Armstrong L, Sviderskaya EV, Negulyaev YA, Klenerman D, Bennett DC, Lako M, Harding SE, Stojkovic M, Korchev YE: "Non-invasive imaging of stem cells by scanning ion conductance microscopy: future perspective". Tissue Eng Part C Methods 14: 311-318 (2008)

Drew D, Newstead S, Sonoda Y, Kim H, von Heijne G, Iwata S: "GFP-based optimization scheme for the overexpression and purification of eukaryotic membrane proteins in Saccharomyces cerevisiae". Nat Protoc 3: 784-798 (2008)

Brito-Martins M, Harding SE, Ali NN: "beta(1)- and beta(2)-adrenoceptor responses in cardiomyocytes derived from human embryonic stem cells: comparison with failing and non-failing adult human heart". Br J Pharmacol 153: 751-759 (2008)

Baldwin GS, Brooks NJ, Robson RE, Wynveen A, Goldar A, Leikin S, Seddon JM, Kornyshev AA: "DNA double helices recognize mutual sequence homology in a protein free environment". J Phys Chem B 112: 1060-1064 (2008)

Windbichler N, Papathanos PA, Catteruccia F, Ranson H, Burt A, Crisanti A: "Homing endonuclease mediated gene targeting in Anopheles gambiae cells and embryos". Nucleic Acids Res 35: 5922-5933 (2007)

Raine JD, Ecker A, Mendoza J, Tewari R, Stanway RR, Sinden RE: "Female inheritance of malarial lap genes is essential for mosquito transmission". PLoS Pathog 3: e30 (2007)

Newstead S, Kim H, von Heijne G, Iwata S, Drew D: "High-throughput fluorescent-based optimization of eukaryotic membrane protein overexpression and purification in Saccharomyces cerevisiae". Proc Natl Acad Sci U S A 104: 13936-13941 (2007)

Lopes VS, Ramalho JS, Owen DM, Karl MO, Strauss O, Futter CE, Seabra MC: "The ternary Rab27a-Myrip-Myosin VIIa complex regulates melanosome motility in the retinal pigment epithelium". Traffic 8: 486-499 (2007)

Ecker A, Pinto SB, Baker KW, Kafatos FC, Sinden RE: "Plasmodium berghei: plasmodium perforin-like protein 5 is required for mosquito midgut invasion in Anopheles stephensi". Exp Parasitol 116: 504-508 (2007)

Onfelt B, Nedvetzki S, Benninger RK, Purbhoo MA, Sowinski S, Hume AN, Seabra MC, Neil MA, French PM, Davis DM: "Structurally distinct membrane nanotubes between human macrophages support long-distance vesicular traffic or surfing of bacteria". J Immunol 177: 8476-8483 (2006)

Hume AN, Tarafder AK, Ramalho JS, Sviderskaya EV, Seabra MC: "A coiled-coil domain of melanophilin is essential for Myosin Va recruitment and melanosome transport in melanocytes". Mol Biol Cell 17: 4720-4735 (2006)

Almeida CR, Davis DM: "Segregation of HLA-C from ICAM-1 at NK cell immune synapses is controlled by its cell surface density". J Immunol 177: 6904-6910 (2006)

Wise EL, Bonner KT, Williams TJ, Pease JE: "A single nucleotide polymorphism in the CCR3 gene ablates receptor export to the plasma membrane". J Allergy Clin Immunol 126: 150-157 e152

Tollis S, Dart AE, Tzircotis G, Endres RG: "The zipper mechanism in phagocytosis: energetic requirements and variability in phagocytic cup shape". BMC Syst Biol 4: 149

Swanwick RS, Pristera A, Okuse K: "The trafficking of Na(V)1.8". Neurosci Lett 486: 78-83

Riches LC, Lynch AM, Gooderham NJ: "A molecular beacon approach to detecting RAD52 expression in response to DNA damage in human cells". Toxicol In Vitro 24: 652-660

Owen DM, Oddos S, Kumar S, Davis DM, Neil MA, French PM, Dustin ML, Magee AI, Cebecauer M: "High plasma membrane lipid order imaged at the immunological synapse periphery in live T cells". Mol Membr Biol 27: 178-189

Mazurek MP, Prasad PD, Gopal E, Fraser SP, Bolt L, Rizaner N, Palmer CP, Foster CS, Palmieri F, Ganapathy V, Stuhmer W, Djamgoz MB, Mycielska ME: "Molecular origin of plasma membrane citrate transporter in human prostate epithelial cells". EMBO Rep 11: 431-437

Lei Y, Overby DR, Read AT, Stamer WD, Ethier CR: "A new method for selection of angular aqueous plexus cells from porcine eyes: a model for Schlemm's canal endothelium". Invest Ophthalmol Vis Sci 51: 5744-5750

Kohler K, Xiong S, Brzostek J, Mehrabi M, Eissmann P, Harrison A, Cordoba SP, Oddos S, Miloserdov V, Gould K, Burroughs NJ, van der Merwe PA, Davis DM: "Matched sizes of activating and inhibitory receptor/ligand pairs are required for optimal signal integration by human natural killer cells". PLoS One 5: e15374

Ibanez-Garcia D, Requejo-Isidro J, Webb MR, West TG, French P, Ferenczi MA: "Fluorescence lifetime imaging reveals that the environment of the ATP binding site of myosin in muscle senses force". Biophys J 99: 2163-2169

Howell OW, Rundle JL, Garg A, Komada M, Brophy PJ, Reynolds R: "Activated microglia mediate axoglial disruption that contributes to axonal injury in multiple sclerosis". J Neuropathol Exp Neurol 69: 1017-1033

Heal WP, Jovanovic B, Bessin S, Wright MH, Magee AI, Tate EW: "Bioorthogonal chemical tagging of protein cholesterylation in living cells". Chem Commun (Camb)

Findon H, Calcagno-Pizarelli AM, Martinez JL, Spielvogel A, Markina-Inarrairaegui A, Indrakumar T, Ramos J, Penalva MA, Espeso EA, Arst HN, Jr.: "Analysis of a novel calcium auxotrophy in Aspergillus nidulans". Fungal Genet Biol 47: 647-655

Fadda L, Borhis G, Ahmed P, Cheent K, Pageon SV, Cazaly A, Stathopoulos S, Middleton D, Mulder A, Claas FH, Elliott T, Davis DM, Purbhoo MA, Khakoo SI: "Peptide antagonism as a mechanism for NK cell activation". Proc Natl Acad Sci U S A 107: 10160-10165

Erasmus J, Aresta S, Nola S, Caron E, Braga VM: "Newly formed E-cadherin contacts do not activate Cdc42 or induce f ilopodia protrusion in human keratinocytes". Biol Cell 102: 13-24

Danks L, Workman S, Webster D, Horwood NJ: "Elevated cytokine product ion restores bone resorption by human Btk-deficient osteoclasts". J Bone Miner Res 26: 182-192

Chauveau A, Aucher A, Eissmann P, Vivier E, Davis DM: "Membrane nanotubes facilitate long-distance interactions between natural killer cells and target cells". Proc Natl Acad Sci U S A 107: 5545-5550

Chaudhury H, Zakkar M, Boyle J, Cuhlmann S, van der Heiden K, Luong le A, Davis J, Platt A, Mason JC, Krams R, Haskard DO, Clark AR, Evans PC: "c-Jun N-terminal kinase primes endothelial cells at atheroprone sites for apoptosis". Arterioscler Thromb Vasc Biol 30: 546-553

Cebecauer M, Spitaler M, Serge A, Magee AI: "Signalling complexes and clusters: functional advantages and methodological hurdles". J Cell Sci 123: 309-320

Caorsi V, Ushakov DS, West TG, Setta-Kaffetzi N, Ferenczi MA: "FRET characterisation for cross-bridge dynamics in single-skinned rigor muscle fibres". Eur Biophys J

Ball SK, Field MC, Tippins JR: "Regulation of thromboxane receptor signaling at multiple levels by oxidative stress-induced stabilization, relocation and enhanced responsiveness". PLoS One 5: e12798

An R, da Silva Xavier G, Semplici F, Vakhshouri S, Hao HX, Rutter J, Pagano MA, Meggio F, Pinna LA, Rutter GA: "Pancreatic and duodenal homeobox 1 (PDX1) phosphorylation at serine-269 is HIPK2-dependent and affects PDX1 subnuclear localization". Biochem Biophys Res Commun 399: 155-161

Ali F, Ali NS, Bauer A, Boyle JJ, Hamdulay SS, Haskard DO, Randi AM, Mason JC: "PPARdelta and PGC1alpha act cooperatively to induce haem oxygenase-1 and enhance vascular endothelial cell resistance to stress". Cardiovasc Res 85: 701-710


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