Guide to the 3Rs & Responsible Animal Research
Research involving the use of animals or animal derived material is expected to be conducted in accordance with good practice standards relating to the responsible use of animals in bioscience research.
This short course will provide a practical guide to meeting the college’s and funder’s expectations with regards animal welfare, implementation of the 3Rs principles of humane experimental technique and standards of contemporary good practice. Content will be discussed in the context of statistics on animal use, public engagement and trends in public opinion, the culture of scientific research in the UK, the research framework, and initiatives to improve experimental design, planning and research reporting standards.
- Overview of animal use in the UK and at Imperial, plus trends in public opinion and initiatives to improve openness and transparency in the use of animals in research
- What is a testable hypothesis?
- How to identify the most appropriate research model/system, including ‘replacement’
- What does ‘responsible use of animals’ mean in practice at Imperial?
- Culture of scientific research in the UK and what can go wrong
- Overview of good practice in experimental design and planning, including common pitfalls and how to avoid them, plus implementing ‘reduction’
- Introduction to animal welfare and what it means in practice for each animals lifetime experience, plus implementing ‘refinement’
- Identifying and managing experimental variables or confounding factors that can impact upon animal welfare
- Critical thinking