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Pioneering research

In the last decade, a number of research groups in Europe and the Americas have conducted studies into the safety and effectiveness of psychedelics for conditions such as depression and post-traumatic stress disorder (PTSD), but the Imperial Centre for Psychedelic Research is the first to gain this level of stature within a major academic institution.

When delivered safely and professionally, psychedelic therapy holds a great deal of promise for treating some very serious mental health conditions.

Dr Robin Carhart-Harris

Head of the Centre for Psychedelic Research

Ours was the first Centre in the world to investigate the brain effects of LSD using modern brain imaging and the first to study psilocybin – the active compound in magic mushrooms – for treating severe depression. These studies have laid the groundwork for larger trials that are now taking place around the world. Other pioneering work from the group includes breakthrough neuroimaging research with psilocybin, MDMA and DMT (the psychoactive compounds found in ecstasy and ayahuasca respectively).

Earlier this year the group began a new trial directly comparing psilocybin therapy with a conventional antidepressant drug in patients with depression – a study for which they are still recruiting volunteers. Building on this, they also plan to begin another new trial next year to explore the safety and feasibility of psilocybin for treating patients with anorexia.

Dr Carhart-Harris adds: “It may take a few years for psychedelic therapy to be available for patients, but research so far has been very encouraging. Early stage clinical research has shown that when delivered safely and professionally, psychedelic therapy holds a great deal of promise for treating some very serious mental health conditions and may one day offer new hope to vulnerable people with limited treatment options.”


If you are a student interested in conducting research with our Centre, please see the page join our research team.

Research publications

Citation

BibTex format

@article{Cofré:2019:10.3390/e21101009,
author = {Cofré, R and Herzog, R and Corcoran, D and Rosas, FE},
doi = {10.3390/e21101009},
journal = {Entropy: international and interdisciplinary journal of entropy and information studies},
pages = {1--20},
title = {A comparison of the maximum entropy principle across biological spatial scales},
url = {http://dx.doi.org/10.3390/e21101009},
volume = {21},
year = {2019}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Despite their differences, biological systems at different spatial scales tend to exhibit common organizational patterns. Unfortunately, these commonalities are often hard to grasp due to the highly specialized nature of modern science and the parcelled terminology employed by various scientific sub-disciplines. To explore these common organizational features, this paper provides a comparative study of diverse applications of the maximum entropy principle, which has found many uses at different biological spatial scales ranging from amino acids up to societies. By presenting these studies under a common approach and language, this paper aims to establish a unified view over these seemingly highly heterogeneous scenarios.
AU - Cofré,R
AU - Herzog,R
AU - Corcoran,D
AU - Rosas,FE
DO - 10.3390/e21101009
EP - 20
PY - 2019///
SN - 1099-4300
SP - 1
TI - A comparison of the maximum entropy principle across biological spatial scales
T2 - Entropy: international and interdisciplinary journal of entropy and information studies
UR - http://dx.doi.org/10.3390/e21101009
UR - https://www.mdpi.com/1099-4300/21/10/1009
UR - http://hdl.handle.net/10044/1/74337
VL - 21
ER -