Group IX - Tetranectin family

Human sequence alignment

Joint human/mouse sequence alignment

Introduction

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SIGNAL SEQUENCE and CHARGED N-TERMINAL TAIL

 

human Tetranectin      MELWGAYLLLCLFSLLTQVTTEPPTQKPKKIVNAKKDVVNTKMFEE

human Cartilage CTL    -MAKNGLVICILVITLLLDQTTSHTSRLKARKHSKRRVRDKDGD

human SCGF             MQAAWLLGALVVPQLLGFGHGARGAEREWEGGWGGAQEEEREREALMLKH

human SCGF             LQEALGLPAGRGDENPAGTVEGKEDWEMEED-QGEEEEEEATPTPSSG----PSPSPTPED

                   

CHARGED RESIDUES

COILED-COIL REGION

 

human Tetranectin      LKSRLDTLAQEVALLKEQQALQTV

human Cartilage CTL    LKTQIEKLWTEVNALKEIQALQTV

human SCGF             IVTYILGRLAGLDAGLHQLHVRLHALDTRVVELTQGLRQLRNAAGDTRDAVQALQEAQGRAEREHGRLEG

 

HEPTAD REPEAT

CTLD

 

human Tetranectin      CLKGTKVHMKCFLAFTQTKTFHEASEDCISRGGTLSTPQTGSENDALYEYLRQSVGNEA--EIWLGLNDMAAEG

human Cartilage CTL    CLRGTKVHKKCYLASEGLKHFHEANEDCISKGGILVIPRNSDEINALQDYGKRSLPGVN--DFWLGINDMVTEG

human SCGF             CLKGLRLGHKCFLLSRDFEAQAAAQARCTARGGSLAQPADRQQMEALTRYLRAALAPYN-WPVWLGVHDRRAEG

 

human Tetranectin      TWVDMTGARIAYKNWETE----------------ITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPYICQFGIV

human Cartilage CTL    KFVDVNGIAISFLNWD-------------------RAQPNGGKRENCVLFSQSAQGKWSDEACRSSKRYICEFTIPQ

human SCGF             LYLFENGQRVSFFAWHRSPRPELGAQPSASPHPLSPDQPNGGTLENCVAQASDD-GSWWDHDCQRRLYYVCEFPF

 

CONSERVED CORE RESIDUES     Ca SITE 1 LIGANDS     Ca SITE 2 LIGANDS (SUGAR-BINDING SITE)

 

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This page last updated:	Thursday, 09 March 2006	Animal lectins home
Contact information:	This site is supported by:
Kurt Drickamer Division of Molecular Biosciences Faculty of Natural Sciences Imperial College London   Email: k.drickamer@imperial.ac.uk