Group IX - Tetranectin family

Joint human/mouse sequence alignment

Human sequence alignment

Introduction

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SIGNAL SEQUENCE and CHARGED N-TERMINAL TAIL

 

human Tetranectin      MELWGAYLLLCLFSLLTQVTTEPPTQKPKKIVNAKKDVVNTKMFEE

mouse Tetranectin      MGFWGTYLLFCLFSFLSQLTAESPTPKAKKAANAKKDLVSSKMFEE

human Cartilage CTL    -MAKNGLVICILVITLLLDQTTSHTSRLKARKHSKRRVRDKDGD

mouse Cartilage CTL    -MAKNGLVLCILVVSLLLDQTDGYPSRMKARKHSKRRVKAKDDD

human SCGF             MQAAWLLGALVVPQLLGFGHGARGAEREWEGGWGGAQEEEREREALMLKH

mouse SCGF             MQAAWLLGALVVPQLLSFGHGARGPGREWEGGWGGALEEERERESQMLKN                   

human SCGF             LQEALGLPAGRGDENPAGTVEGKEDWEMEED-QGEEEEEEATPTPSSG----PSPSPTPED

mouse SCGF             LQEALGLPTGVGNEDNLAENPEDKEVWETTETQGEEEEEEITTAPSSSPNPFPSPSPTPED

                   

CHARGED RESIDUES

COILED-COIL REGION

 

human Tetranectin      LKSRLDTLAQEVALLKEQQALQTV

mouse Tetranectin      LKNRMDVLAQEVALLKEKQALQTV

human Cartilage CTL    LKTQIEKLWTEVNALKEIQALQTV

mouse Cartilage CTL    LKSQVEKLWREVNALKEMQALQTV

 

human SCGF             IVTYILGRLAGLDAGLHQLHVRLHALDTRVVELTQGLRQLRNAAGDTRDAVQALQEAQGRAEREHGRLEG

mouse SCGF             TVTYILGRLASLDAGLHQLHVRLHVLDTRVVELTQGLRQLRDAASDTRDSVQALKEVQDRAEQEHGRLEG

 

HEPTAD REPEAT

CTLD

 

human Tetranectin      CLKGTKVHMKCFLAFTQTKTFHEASEDCISRGGTLSTPQTGSENDALYEYLRQSVGNEA--EIWLGLNDMAAEG

mouse Tetranectin      CLKGTKVNLKCLLAFTQPKTFHEASEDCISQGGTLGTPQSELENEALFEYARHSVGNDA--NIWLGLNDMAAEG

human Cartilage CTL    CLRGTKVHKKCYLASEGLKHFHEANEDCISKGGILVIPRNSDEINALQDYGKRSLPGVN--DFWLGINDMVTEG

mouse Cartilage CTL    CLRGTKVHKKCYLASEGLKHYHEANEDCISKGGTLVVPRNSDEINALRDYGKRSLPGVN--DFWLGINDMVTEG

human SCGF             CLKGLRLGHKCFLLSRDFEAQAAAQARCTARGGSLAQPADRQQMEALTRYLRAALAPYN-WPVWLGVHDRRAEG

mouse SCGF             CLKGLRLGHKCFLLSRDFETQAAAQARCKARGGSLAQPADRQQMDALSRYLRAALAPYN-WPVWLGVHDRRSEG

 

human Tetranectin      TWVDMTGARIAYKNWETE----------------ITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPYICQFGIV

mouse Tetranectin      AWVDMTGGLLAYKNWETE----------------ITTQPDGGKAENCAALSGAANGKWFDKRCRDQLPYICQFAIV

human Cartilage CTL    KFVDVNGIAISFLNWD-------------------RAQPNGGKRENCVLFSQSAQGKWSDEACRSSKRYICEFTIPQ

mouse Cartilage CTL    KFLDVHGFAVSFLNWD-------------------RAQPSGGKRENCVLFSQSAQGKWSDEACRSSKRYICEFIIP

human SCGF             LYLFENGQRVSFFAWHRSPRPELGAQPSASPHPLSPDQPNGGTLENCVAQASDD-GSWWDHDCQRRLYYVCEFPF

mouse SCGF             LYLFENGQRVSFFAWHRAFSLESGAQPSAATHPLSPDQPNGGVLENCVAQASDD-GSWWDHDCERRLYFVCEFPF

 

CONSERVED CORE RESIDUES     Ca SITE 1 LIGANDS     Ca SITE 2 LIGANDS (SUGAR-BINDING SITE)

 

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This page last updated:	Thursday, 09 March 2006	Animal lectins home
Contact information:	This site is supported by:
Kurt Drickamer Division of Molecular Biosciences Faculty of Natural Sciences Imperial College London   Email: k.drickamer@imperial.ac.uk