Group VII - Free CTLD / Reg
group
- Joint human/mouse sequence alignment
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Mammalian
proteins containing CTLDs
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If alignments appear scrambled please maximize the width of your browser
window.
SIGNAL
SEQUENCE and N-TERMINAL PEPTIDE
human
Lit.a
MAQTSSYFMLISCLMFLSQSQG-------QEAQTELPQARI
mouse
Lit.a
MARNAYFILLSCLIVLSPSQG-------QEAEEDLPSARI
human
Lit.b
MAQTNSFFMLISSLMFLSLSQG-------QESQTELPNPRI
mouse
Lit.b MAQNNVYLILFLCLMFLSYSQGQVAEEDFPLAEKDLPSAKI
human
PAP/HIP MLPPMALPSVSWMLLSCLMLLSQVQG-------EEPQRELPSARI
mouse
PAP1 MLPPTACSVMSWMLLSCLMLLSQVQG-------EDSLKNIPSARI
mouse
PAP2 MLPHLVLNSISWMLLSCLLFVFQVQG-------EDFQKEVPSPRT
mouse
PAP3 MLPRITITIMSWMLLSCLMLLSQVQG-------EVAKKDAPSSRS
mouse Reg3d
MVSHKTLHSMSWMLLCCLMSLSWVQG-------EQSQKKLSSPRI
human
Reg4
MASRSMRLLLLLSCLAKTG-VLGDI-IMRP
mouse
Reg4
MAYKGVRLLLLLSWVAGPE-VLSD--ILRP
SIGNAL
SEQUENCE
CTLD
human
Lit.a SCPEGTNAYRSYCYYFNEDRETWVDADLYCQNMNSG-NLVSVLTQAEGAFVASLIKESGTDDFNVWIGLHDPKK--
mouse
Lit.a SCPEGSNAYSSYCYYFTEDRLTWADADLFCQNMNSG-YLVSVLSQAEGNFVASLIKESGTTDANVWTGLHDPKR--
human
Lit.b SCPEGTNAYRSYCYYFNEDPETWVDADLYCQNMNSG-NLVSVLTQAEGAFVASLIKESSTDDSNVWIGLHDPKK--
mouse
Lit.b NCPEGANAYGSYCYYLIEDRLTWGEADLFCQNMNAG-HLVSILSQAESNFVASLVKESGTTASNVWTGLHDPKS--
human
PAP/HIP RCPKGSKAYGSHCYALFLSPKSWTDADLACQKRPSG-NLVSVLSGAEGSFVSSLVKSIGNSYSYVWIGLHDPTQGT
mouse
PAP1 SCPKGSQAYGSYCYALFQIPQTWFDAELACQKRPGG-HLVSVLNSAEASFLSSMVKRTGNSYQYTWIGLHDPTLGA
mouse
PAP2 SCPMGYKAYRSHCYALVMTPKSWFQADLVCQKRPSG-HLVSILSGGEASFVSSLVNGRVDNYQDIWIGLHDPTMGQ
mouse
PAP3 SCPKGSRAYGSYCYALFSVSKNWYDADMACQKRPSG-HLVSVLSGAEASFLSSMIKSSGNSGQYVWIGLHDPTLGY
mouse Reg3d SCPQEAQAYGSYCYLLILEPQTWANAEIHCQKHFSG-HLAFLLTYGEIIFVSSLVKNSLTTFPYIWIGLHDLSLGS
human
Reg4 SCAPGWFYHKSNCYGYFRKLRNWSDAELECQSYGNGAHLASILSLKEASTIAEYISGYQRSQP-IWIGLHDPQK--
mouse
Reg4 SCAPGWFYYRSHCYGYFRKLRNWSHAELECQSYGNGSHLASVLNQKEASVISKYITGYQRNLP-VWIGLHDPQK--
human
Lit.a --NRR-WHWSSGSLVSYKSWGIGAPSSVNPGYCVSLTSSTGFQKWKDVPCEDKFSFVCKFKN
mouse
Lit.a --NRR-WHWSSGSLFLYKSWATGSPNSSNRGYCVSLTSNTGYKKWKDDNCDAQYSFVCKFKG
human
Lit.b --NRR-WHWSSGSLVSYKSWDTGSPSSANAGYCASLTSCSGFKKWKDESCEKKFSFVCKFKN
mouse
Lit.b --NRR-WHWSSGSLFLFKSWATGAPSTANRGYCVSLTSNTAYKKWKDENCEAQYSFVCKFRA
human
PAP/HIP EPNGEGWEWSSSDVMNYFAWERNPSTISSPGHCASLSRSTAFLRWKDYNCNVRLPYVCKFTD
mouse
PAP1 EPNGGGWEWSNNDVMNYFNWERNPSTALDRAFCGSLSRASGFLKWRDMTCEVKLPYVCKFTG
mouse
PAP2 QPNGGGWEWSNSDVLNYLNWDGDPSSTVNRGHCGSLTASSGFLKWGDYYCDGTLPFVCKFKQ
mouse
PAP3 EPNRGGWEWSNADVMNYINWETNPSSSSGN-HCGTLSRASGFLKWRENYCNLELPYVCKFKA
mouse Reg3d
LPNENGWKWSSSDPLTFYNWEIPPSMSAHHGYCAALSQASGYQKWRDYYCDPTFPYVCKFKG
human
Reg4 --RQQ-WQWIDGAMYLYRSWS--GKSMGGNKHCAEMSSNNNFLTWSSNECNKRQHFLCKYRP
mouse
Reg4 --KQL-WQWTDGSTNLYRRWN--PRTKSEARHCAEMNPKDKFLTWNKNGCANRQHFLCKYKT
CONSERVED
CORE RESIDUES
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- This page last updated:
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Thursday, 09 March 2006
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Animal
lectins home
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This site is
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- Kurt Drickamer
- Division of Molecular Biosciences
- Faculty of Natural Sciences
- Imperial College London
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- Email:
k.drickamer@imperial.ac.uk
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