Animal lectins - References
	Jump to:- Calnexin   M-type   L-type   P-type   Galectins   I-type   R-type F-box   Ficolins   Chitinase-like F-type   Intelectins

 

Calnexin Family

 

• Parodi, A.J. (2000) Role of N-oligosaccharides endoplasmic reticulum processing reactions in glycoprotein folding and degradation. Biochem. J., 348, 1-13.

• Trombetta, E.S. and Helenius, A. (1998) Lectins as chaperones in glycoprotein folding. Cur. Opin. Struct. Biol., 8, 587-592.

• Schrag, J.D., Bergeron, J.J., Li, Y., Borisova, S., Hahn, M., Thomas, D.Y., Cygler, M. (2001)  The structure of calnexin, an ER chaperone involved in quality control of protein folding.  Mol. Cell, 8, 633-644.

• Thomson, S.P., Williams, D.B. (2005) Delineation of the lectin site of the molecular chaperone calreticulin.  Cell Stress Chaperones, 10, 242-251.

• Watanabe, D., Yamada, K., Nishina, Y., Tajima, Y., Koshimizu, U., Nagata, A., Nishimune, Y. (1994)  Molecular cloning of a novel Ca2+-binding protein (calmegin) specifically expressed during meiotic germ cell development.  J. Biol. Chem., 269, 7744-7749.

• Ohsako, S., Hayashi, Y., Bunick, D. (1994)  Molecular cloning and sequencing of calnexin-t.  An abundant male germ cell-specific calcium-binding protein of the endoplasmic reticulum.  J. Biol. Chem., 269, 14140-14148.

• Tanaka, H., Ikawa, M., Tsuchida, J., Nozaki, M., Suzuki, M., Fujiwara, T., Okabe, M., Nishimune, Y. (1997)  Cloning and characterization of the human calmegin gene encoding putative testis-specific chaperone.  Gene, 204, 156-163.

• Ikawa, M., Wada, I., Kominami, K., Watanabe, D., Toshimori, K., Nishimune, Y., Okabe, M. (1997)  The putative chaperone calmegin is required for sperm fertility.  Nature, 387, 607-611.

• Persson, S., Rosenquist, M., Sommarin, M. (2002)  Identification of a novel calreticulin isoform (Crt2) in human and mouse.  Gene, 297, 151-158.

• Williams, D.B. (2006) Beyond lectins: the calnexin/calreticulin chaperone system of the endoplasmic reticulum.  J. Cell Sci., 119, 615-623.

 

 

M-type lectins

 

• Braakman, I. (2001) A novel lectin in the secretory pathway: an elegant mechanism for glycoprotein elimination. EMBO Reports 2, 666-668.

• Hosokawa, N., Wada, I., Hasegawa, K., Yorihuzi, T., Tremblay, L.O., Herscovics, A. and Nagata, K. (2001) A novel ER a-mannosidase-like protein accelerates ER-associated degradation. EMBO Reports 2, 415-422.

• Jakob, C.A., Bodmer, D., Spirig, U., Battig, P., Marcil, A., Dignard, D., Bergeron, J.J.M., Thomas, D.Y. and Aebi, M. (2001) Htm1p, a mannosidase-like protein, is involved in glycoprotein degradation in yeast. EMBO Reports 2, 423-430.

• Nakatsukasa, K., Nishikawa, S., Hosokawa, N., Nagata, K. and Endo, T. (2001) Mnl1p, an a-mannoside-like protein in yeast Saccharomyces cerevisiae, is required for endoplasmic reticulum-associated degradation of glycoproteins. J. Biol. Chem. 276, 8635-8638

• Mast, S.W., Diekman, K., Karaveg, K., Davis, A., Sifers, R.N., Moremen, K.W. (2005) Human EDEM2, a novel homolog of family 47 glycosidases, is involved in ER-associated degradation of glycoproteins.  Glycobiology, 15, 421-436.  Erratum: 15, 13G.

• Olivari, S., Galli, C., Alanen, H., Ruddock, L., Molinari, M (2005) A novel stress-induced EDEM varient regulating endoplasmic reticulum-associated glycoprotein degradation.  J. Biol. Chem., 280, 2424-2428.

• Hirao, K., Natsuka, Y., Tamura, T., Wada, I., Morito, D., Natsuka, S., Romero, P., Sleno, B., Tremblay, L.O., Herscovics, A., Nagata, K., Hosokawa, N. (2006) EDEM3, a soluble EDEM homolog, enhances glycoprotein endoplasmic reticulum-associated degradation and mannose trimming.  J. Biol. Chem., 218, 9650-9658.

 

L-type lectins

 

• Sharon, N. and Lis, H. (1990) Legume lectins: a large family of homologous proteins. FASEB J., 4, 3198-3208.

• Fiedler, K. and Simons, K. (1994) A putative novel class of animal lectins in the secretory pathway homologous to leguminous lectins. Cell, 77, 625-626.

Itin, C., Roche, A.C., Monsigny, M. and Hauri, H.P. (1996) ERGIC-53 is a functional mannose-selective and calcium-dependent human homologue of leguminous lectins. Mol. Biol. Cell, 7, 483-493.

• Rini, J.M. (1995) Lectin structure. Annu. Rev. Biophys. Biomol. Struct., 24, 551-577.

• Sharma, V. and Surolia, A. (1997) Analyses of carbohydrate recognition by legume lectins: size of the combining site loops and their primary specificity. J. Mol. Biol., 267, 433-445.Yerushalmi, N., Keppler-Hafkemeyer, A., Vasmatzis, G., Liu, X.F., Olsson, P., Bera, T.K., Duray, P., Lee, B., Pastan, I. (2001) ERGL, a novel gene related to ERGIC-53 that is highly expressed in normal and neoplastic prostate and several other tissues.  Gene, 265, 55-60.

• Nufer, O., Mitrovic, S., Hauri, H-P. (2003) profile-based data base scanning for manimal L-type lectins and characterization of VIPL, a novel VIP36-like endoplasmic reticulum protein. J. Biol. Chem., 278, 15886-15896.

• Kamiya, Y., Yamaguchi, Y., Takahashi, N., Arata, Y., Kasai, K., Ihara, Y., Matsuo, I., Ito, Y., Yamamoto, K., Kato, K. (2005) Sugar-binding properties of VIP36, an intracellular animal lectin operating as a cargo receptor. J. Biol. Chem., 280, 37178-37182.

• Satoh, T., Sato, K., Kanoh, A., Yamashita, K., Yamada. Y., Igarashi, N., Kato, R., Nakano, A., Wakatsuki, S. (2006) Structures of the carbohydrate recognition domain of Ca2+-independent cargo receptors Emp46p and Emp47p.  J. Biol. Chem., 281, 10410-10419.

 

 

P-type lectins

 

• Dahms, N.M., Lobel, P. and Kornfeld, S. (1989) Mannose 6-phosphate receptors and lysosomal enzyme targeting. J. Biol. Chem., 264, 12115-12118.

• Roberts, D.L., Weix, D.J., Dahms, N.M. and Kim, J.-J.P. (1998) Molecular basis of lysosomal enzyme recognition: three-dimensional structure of the cation-dependent mannose 6-phosphate receptor. Cell, 93, 639-648.

• Munro, S. (2001) The MRH domain suggests a shared ancestry for the mannose 6-phosphate receptors and other N-glycan-recognising proteins. Current Biology, 11, R499-501.

• Whyte, J.R.C., Munro, S. (2001) A yeast homologue of the mammalian mannose 6-phosphate rceptors contributes to the sorting of vacuolar hydrolases.  Current Biology, 11, 1074-1078.

• Cormier, J.H., Pearse, B.R., Hebert, D.N. (2005) Yos9p: A sweet-toothed bouncer of the secretory pathway.  Mol. Cell, 19, 717-726.

• Bhamidipati, A., Denic, V., Quan, E.Q., Weissman, J.S. (2005) Exploration of the topological requirements of ERAD identifies Yos9p as a lectin sensor of misfolded glycoproteins in the ER lumen.  Mol. Cell, 19, 741-751.

• Kim, W., Spear, E.D., Ng, D.T.W. (2001) Yos9p detects and targets misfolded glycoproteins for ER-associated degradation. Mol. Cell, 19, 753-764.

• Szathmary, R., Bielmann, R., Nita-Lazar, M., Burda, P., Jakob, C.A. (2005) Yos9 protein is essential for degradation of misfolded glycoproteins and may function as a lectin in ERAD.  Mol. Cell, 19, 765-775.

• Cruciat, C-M., Hassler, C., Niehrs, C. (2006) The MRH protein erlectin is a member of the endoplasmic reticulum synexpression group and functions in N-glycan recognition.  J. Biol. Chem., 281, 12986-12993.

 

Galectins

 

• Barondes, S.H., Cooper, D.N.W., Gitt, M.A. and Leffler, H. (1994) Galectins structure and function of a large family of animal lectins. J. Biol. Chem., 269, 20807-20810.

Cooper, D.N.W. and Barondes, S.H. (1999) God must love galectins; He made so many of them. Glycobiology, 9, 979-984.

• Leonidas, D.D., Vatzaki, E.H., Vorum, H., Celis, J.E., Madsen, P. and Acharya, K.R. (1998) Structural basis for the recognition of carbohydrates by human galectin-7. Biochemistry, 37, 13930-13940.

• Liao, D.-I., Kapadia, G., Ahmed, H., Vasta, G.R. and Herzberg, O. (1994) Structure of S-lectin, a developmentally regulated vertebrate a-galactoside-binding protein. Proc. Natl. Acad. Sci. U.S.A., 91, 1428-1432.

• Lobsanov, Y.D., Gitt, M.A., Leffler, H., Barondes, S.H. and Rini, J.M. (1993) X-ray crystal structure of the human dimeric S-Lac lectin, L-14-II, in complex with lactose at 2.9-Å resolution. J. Biol. Chem., 268, 27034-27038.

• Swaminathan, G.J., Leonidas, D.D., Savage, M.P., Ackerman, S.J. and Acharya, K.R. (1999) Selective recognition of mannose by the human eosinophil Charcot-Leydon crystal protein (Galectin 10): a crystallographic study at 1.8 Å resolution. Biochemistry, 38, 13837-13843.

 

I-type lectins

 

• Crocker, P., Clark, E.A., Filbin, M., Gordon, S., Jones, Y., Kehrl, J.H., Kelm, S., Le Douarin, N., Powell, L., Roder, J., Schnaar, R.L., Sgroi, D.C., Stamenkovic, K., Schauer, R., Schachner, M., van den Berg, T.K., van der Merwe, P.A., Watt, S.M. and Varki, A. (1998) Siglecs: a family of sialic-acid binding lectins. Glycobiology, 8, v.

• Crocker, P.R. and Varki, A. (2001) Siglecs in the immune system.  Immunology, 103, 137-145.

• Crocker, P.R. and Varki, A. (2001) Siglecs, sialic acid and innate immunity.  Trends in Immunology, 22, 337-342.

• Nitchke, L. (2005) The role of CD22 and other inhibitory co-receptors in B-cell activation.  Curr. Opin. Immunol., 17, 290-297.

 

R-type lectins

 

• Clausen, H. and Bennett, E.P. (1996) A family of UDP-GalNAc: polypeptide N-acetylgalactosaminyl-transferases control the initiation of mucin type O-linked glycosylation. Glycobiology, 6, 635-646.

• Fiete, D.J., Beranek, M.C. and Baenziger, J.U. (1998) A cysteine-rich domain of the "mannose" receptor mediates GalNAc-4-SO4 binding. Proc. Natl. Acad. Sci. U.S.A., 95, 2089-2093.

• Fujimoto, Z., Kuno, A., Kaneko, S., Yoshida, S., Kobayashi, H., Kusakabe, I. and Mizuno, H. (2000) Crystal structure of Streptomyces olivaceoviridis E-86 b-xylanase containing xylan-binding domain. J. Mol. Biol., 300, 575-585.

• Liu, Y., Chirino, A.J., Misulovin, Z., Leteux, C., Feizi, T., Nussenzweig, M.C. and Bjorkman, P.J. (2000) Crystal structure of the cysteine-rich domain of mannose receptor complexed with a sulfated carbohydrate ligand. J. Exptl. Med., 191, 1105-1115.

• Hassan, H., Reis, C.A., Bennett, E.P., Mirgorodskaya, E., Roepstorff, P., Hollingsworth, M.A., Burchell, J., Taylor-Papadimitiou, J. and Clausen, H. (2000) The lectin domain of UDP-N-acetyl-D-galactosmine:polypeptide N-acetylgalactosaminyltransferase-T4 direct its glycopeptide specificities. J. Biol. Chem., 275, 38197-38205.

• Murzin, A.G., Lesk, A.M. and Chothia, C. (1992) Beta-trefoil fold patterns of structure and sequence in the Kunitz inhibitors, interleukins-1b and 1a and fibroblast growth factors. J. Mol. Biol., 223, 531-543.

• Rutenber, E., Ready, M. and Robertus, J.D. (1987) Structure and evolution of ricin B chain. Nature, 326, 624-626.

• Rutenber, E. and Robertus, J.D. (1991) Structure of ricin B-chain at 2.5 Å resolution. Proteins, 10, 260-269.

• Taylor, M.E. (1997) Evolution of a family of receptors containing multiple motifs resembling carbohydrate-recognition domains. Glycobiology, 7, R5-R8.

 

F-box lectins

 

• Mizushima, T., Hirao, T., Yoshida, Y., Lee, S.J., Chiba, T., Iwai, K., Yamaguchi, Y., Kato, K., Tsukihara, T., Tanaka, K. (2004)  Structural basis of sugar-recognizing ubiquitin ligase.  Nat. Struct. Mol. Biol., 11, 365-370.

• Yoshida, Y., Tokunaga, F., Chiba, T., Iwai, K., Tanaka, K., Tai, T. (2003) Fbs2 a new member of the E3 ubiquitin ligase family that recognizes sugar chains.  J. Biol. Chem., 278, 43877-43884.

• Yoshida, Y., Adachi, E., Fukiya, K., Iwai, K., Tanaka, K. (2005)  Glycoprotein-specific ubiquitin ligases recognize N-glycans in unfolded substrates.  EMBO Rep, 6, 239-244.

 

Ficolins

 

• Ohashi, T., Erickson, H.P. (1997) Two oligomeric forms of plasma ficolin have differential lectin activity.  J. Biol. Chem., 272, 14220-14226.

• Matsushita, M., Fujita, T. (2001) Ficolins and the lectin complement pathway.  Immunological Reviews, 180, 78-85.

• Ohashi, T., Erickson, H.P. (2004) The disulfide bonding pattern in ficolin mutlimers.  J. Biol. Chem., 279, 6534-6539.

• Ma, Y.G., Cho, M.Y, Zhao, M., Park, J.W., Matsushita, M., Fujita, T., Lee, B.L. (2004)  Human mannose-binding lectin and L-ficolin function as specific pattern recognition proteins in the lectin activation pathway of complement.  J. Biol. Chem., 279, 25307-25312.

• Krarup, A., Thiel, S., Hansen, A., Fujita, T., Jensenius, J.C. (2004)  L-ficolin is a pattern recognition molecule specific for acetyl groups.  J. Biol. Chem., 279, 47513-47519.

• Gokudan, S., Muta, T., Tsuda, R., Koori, K., Kawahara, T., Seki, N., Mizunoe, Y., Wai, S.W., Iwanaga, S., Kawabata, S-I. (1999)  Horseshoe crab acetyl group-recognizing lectins involved in innate immunity are structurally related to fibrinogen.  Proc. Natl. Acad. Sci. USA, 96, 10086-10091.

 

Chitinase-like lectins

 

• Chang, N-C.A., Hung, S-I., Hwa, K-Y., Kato, I., Chen, J-E., Liu, C-H., Chang, A.C. (2001) A macrophage protein, Ym1, transiently expressed during inflammation is a novel mammalian lectin.  J. Biol. Chem., 276, 17497-17506.

• Sun, Y-J., Chang, N-C.A., Hung, S-I., Chang, A.C., Chou, C-C., Hsiao, C-D. (2001) The crystal structure of a novel mammalian lectin, Ym1, suggests a saccharide binding site.  J. Biol. Chem., 276, 17507-17514.

• Tsai, M.L., Liaw, S.H., Chang, N.C. (2004) The crystal structure of Ym1 at 1.31 A resolution.  J. Struct. Biol., 148, 290-296.

• Fusetti, F., von Moeller, H., Houston, D., Rozeboom, H.J., Dijkstra, B.W., Boot, R.G., Aerts, J.M.F.G, van Aalten, D.M.F. (2002) Structure of human chitotriosidase.  J. Biol. Chem., 277, 25537-25544.

• Fusetti, F., Pijning, T., Kalk, K.H., Bos, E., Dijkstra, B.W. (2003) Crystal structure and carbohydrate-binding properties of the human cartilage glycoprotein-39.  J. Biol. Chem., 278, 37753-37760.

• Bigg, H.F., Wait, R., Rowan, A.D., Cawston, T.E. (2006) The mammalian chitinase-like lectin, YKL-40, binds specifically to type I collagen and modulates the rate of type I collagen fibril formation.  J. Biol. Chem., 281, 21083-21095.

 

F-type lectins (fucolectins)

 

• Saito, T., Hatada, M., Iwanaga, S., Kawabata, S. (1997)  A newly identified horseshoe crab lectin with binding specificity to O-antigen of bacterial lipopolysaccharides.  J. Biol. Chem., 272, 30703-30708.

• Honda, S., Kashiwagi, M., Miyamoto, K., Takei, Y., Hirose, S. (2000) Multiplicity, structures, and endocrine and exocrine natures of eel fucose-binding lectins.  J. Biol. Chem., 275, 33151-33157.

• Bianchet, M.A., Odom, E.W., Vasta, G.R., Amzel, L.M. (2002)  A novel fucose recognition fold involved in innate immunity.  Nature. Struct. Biol., 9, 628-634.

• Vasta, G.R., Ahmed, H., Odom, E.W. (2004)  Structural and functional diversity of lectin repertoires in invertebrates, protochordates and ectothermic vertebrates.  Curr. Op. Struct. Biol., 14, 617-630.

• Vasta, G.R., Odom, E.W. (2006) Characterization of a binary tandem domain F-type lectin from striped bass (Morone saxatilis).  J. Biol. Chem., 281, 1698-1713.

• Boraston, A.B., Wang, D., Burke, R.D. (2006)  Blood group antigen recognition by a Streptococcus pneumoniae virulence factor.  J. Biol. Chem., in press.

 

Intelectins

 

• Nagata, S., Nakanishi, M., Nanba, R., Fujita, N. (2003)  Developmental expression of XEEL, a novel molecule of the Xenopus oocyte cortical granule lectin family.  Dev. Genes Evol., 213, 368-370.

• Chang, B.Y., Peavy, T.R., Wardrip, N.J., Hedrick, J.L. (2004)  The Xenopus laevis cortical granule lectin: cDNA cloning, developmental expression, and identification of the eglectin family of lectins.  Comp. Biochem. Physiol. A. Mol. Integr. Physiol., 137, 115-129.

• Abe, Y., Tokuda, M., Ishimoto, R., Azumi, K., Yokosawa, H. (1999)  A unique primary structure, cDNA cloning and function of a galactose-specific lectin from ascidian plasma.  Eur. J. Biochem., 261, 33-39.

• Komiya, T., Tanigawa, Y., Hirohashi, S. (1998) Cloning of the novel gene intelectin, which is expressed in intestinal paneth cells in mice.  Biochem. Biophys. Res. Commun., 251, 759-762.

• Pemberton, A.D., Knight, P.A., Gamble, J., Colledge, W.H., Lee, J.K., Pierce, M., Miller, H.R. (2004)  Innate BALB/c enteric epithelial responses to Trichinella spiralis: inducible expression of a novel goblet cell lectin, intelectin-2, and its natural deletion in C57BL/10 mice.  J. Immunol., 173, 1894-1901.

• Tsuji, S., Uehori, J., Matsumoto, M., Suzuki, Y., Matsuhisa, A., Toyoshima, K., Seya, T. (2001)  Human intelectin is a novel soluble lectin that recognizes galactofuranose in carbohydrate chains of bacterial cell wall.  J. Biol. Chem., 276, 23456-23463.

• Suzuki, Y.A., Shin, K., Lonnerdal, B. (2001)  Molecular cloning and functional expression of a human intestinal lactoferrin receptor.  Biochemistry, 40, 15771-15779.

• Lee, J.K, Schnee, J., Pang, M., Wolfert, M., Baum, L.G., Moremen, K.W., Pierce, M. (2001) Human homologs of the Xenopus oocyte cortical granule lectin XL35.  Glycobiology, 11, 65-73.

• Schaffler, A., Neumeier, M., Herfarth, H., Furst, A., Scholmerich, J., Buchler, C. (2005)  Genomic structure of human omentin, a new adipocytokine expressed in omental adipose tissue.  Biochim. Biophys. Acta., 1723, 96-102.

• Wrackmeyer, U., Hansen, G.H., Seya, T., Danielsen, E.M. (2006)  Intelectin: a novel lipid raft-associated protein in the enterocyte brush border.  Biochemistry, 45, 9188-9197.

• Lee, J.K., Baum, L.G., Moremen, K., Pierce, M. (2004)  The X-lectins: a new family with homology to the Xenopus laevis oocyte lectin XL-35.  Glycoconj. J., 21, 443-450.

 

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This page last updated:	Wednesday, 18 October 2006	Animal lectins home
Contact information:	This site is supported by:
Kurt Drickamer Division of Molecular Biosciences Faculty of Natural Sciences Imperial College London   Email: k.drickamer@imperial.ac.uk