TY - JOUR AB - Functions of EBER RNAs were tested in lymphoblastoid cell lines containing EBER mutants of Epstein-Barr Virus (EBV). Binding of EBER1 to RPL22 was confirmed. Deletion of EBER1 or EBER2 correlated with increased cytoplasmic EBV LMP2 RNA and with small effects on specific cellular miRNA levels but protein levels of LMP1 and LMP2A were not affected. Wild type and EBER deletion EBV had approximately equal ability to infect immunodeficient mice reconstituted with a human haematopoietic system. AU - Gregorovic,G AU - Boulden,EA AU - Bosshard,R AU - Karstegl,CE AU - Skalsky,R AU - Cullen,BR AU - Gujer,C AU - Rämer,P AU - Münz,C AU - Farrell,PJ DO - 10.1128/JVI.01873-15 EP - 11714 PY - 2015/// SN - 1098-5514 SP - 1171 TI - Epstein-Barr viruses deficient in EBER RNAs give higher LMP2 RNA expression in lymphoblastoid cell lines and efficiently establish persistent infection in humanized mice. T2 - Journal of Virology UR - http://dx.doi.org/10.1128/JVI.01873-15 UR - http://hdl.handle.net/10044/1/26502 VL - 89 ER -