TY - JOUR AB - OBJECTIVE: HIV testing services (HTS) are a crucial component of national HIV responses. Learning one's HIV diagnosis is the entry point to accessing life-saving antiretroviral treatment and care. Recognizing the critical role of HTS, the Joint United Nations Programme on HIV/AIDS (UNAIDS) launched the 90-90-90 targets stipulating that by 2020, 90% of people living with HIV know their status, 90% of those who know their status receive antiretroviral therapy, and 90% of those on treatment have a suppressed viral load. Countries will need to regularly monitor progress on these three indicators. Estimating the proportion of people living with HIV who know their status (i.e., the "first 90"), however, is difficult. METHODS: We developed a mathematical model (henceforth referred to as "F90") that formally synthesizes population-based survey and HTS program data to estimate HIV status awareness over time. The proposed model uses country-specific HIV epidemic parameters from the standard UNAIDS Spectrum model to produce outputs that are consistent with other national HIV estimates. The F90 model provides estimates of HIV testing history, diagnosis rates, and knowledge of HIV status by age and sex. We validate the F90 model using both in-sample comparisons and out-of-sample predictions using data from three countries: Côte d'Ivoire, Malawi, and Mozambique. RESULTS: In-sample comparisons suggest that the F90 model can accurately reproduce longitudinal sex-specific trends in HIV testing. Out-of-sample predictions of the fraction of PLHIV ever tested over a 4-to-6-year time horizon are also in good agreement with empirical survey estimates. Importantly, out-of-sample predictions of HIV knowledge are consistent (i.e., within 4% points) with those of the fully calibrated model in the three countries when HTS program data are included. The F90 model's predictions of knowledge of status are higher than available self-reported HIV awareness estimates, howe AU - Maheu-Giroux,M AU - Marsh,K AU - Doyle,C AU - Godin,A AU - Delaunay,CL AU - Johnson,LF AU - Jahn,A AU - Abo,K AU - Mbofana,F AU - Boily,M-C AU - Buckeridge,DL AU - Hankins,C AU - Eaton,JW DO - 10.1097/QAD.0000000000002386 EP - 269 PY - 2019/// SN - 0269-9370 SP - 255 TI - National HIV testing and diagnosis coverage in sub-Saharan Africa: a new modeling tool for estimating the "first 90" from program and survey data T2 - AIDS UR - http://dx.doi.org/10.1097/QAD.0000000000002386 UR - https://www.ncbi.nlm.nih.gov/pubmed/31764066 UR - https://insights.ovid.com/crossref?an=00002030-900000000-96771 UR - http://hdl.handle.net/10044/1/75346 VL - 33 ER -