Certain pathogens, toxins and their genetic materials are controlled under the Anti-Terrorism, Crime and Security Act (ATCSA). Principal investigators who wish to acquire, possess or use any of these agents or materials must notify, and obtain consent from, the College Biosafety Team. Before such consent can be given it will be necessary to ensure that the security measures provided are in compliance with those required under published national security requirements. Consent shall not be provided until the Home Office has been notified and the Counter Terrorism Security Adviser (CTSA) has been informed and the latter has had the opportunity to inspect the facility proposed for this use.

Central to the College’s counter terrorism strategy is the need to protect vulnerable individuals from being radicalised or drawn into terrorism. In accordance with the requirements of the Counter-Terrorism and Security Act 2015, a protocol has been published by the College for the purpose of detecting and preventing the radicalisation of individuals (published by the College Secretariat). The effective implementation of the protocol will aid the identification of vulnerable individuals and limit the threat posed by such individuals in relation to College’s biological holdings.          

Security standards for Schedule 5 pathogens and toxins

The list of pathogens and toxins controlled under the ATCSA is provided within Schedule 5 of the Act. See below for the current list of Schedule 5 pathogens and toxins. Guidance on the interpretation of the list and when material held falls within the scope of the Act is available from the College Biosafety Team as is more information on the security requirements for working with such material.

Schedule 5 pathogens and toxins

Schedule 5 pathogens and Toxins

Viruses affecting humans

Chikungunya virus

Congo-Crimean haemorrhagic fever virus

Dengue fever virus

Dobrava/Belgrade virus

Eastern equine encephalitis virus

Ebola virus

Everglades virus

Getah virus Guanarito virus

Hantaan virus

Hendra virus (Equine morbillivirus)

Herpes simiae (B virus)

Influenza viruses (pandemic strains)

Japanese encephalitis virus

Junin virus

Kyasanur Forest virus

Lassa fever virus

Louping ill virus

Lymphocytic choriomeningitis virus

Machupo virus

Marburg virus

Mayaro virus

Middleburg virus

Mobala virus

Monkey pox virus

Mucambo virus

Murray Valley encephalitis virus

Ndumu virus

Nipah virus

Omsk haemorrhagic fever virus

Polio virus

Powassan virus

Rabies virus

Rift Valley fever virus

Rocio virus

Sabia virus

Sagiyama virus

SARS Coronavirus

Sin Nombre virus

St Louis encephalitis virus

Tick-borne encephalitis virus (Russian Spring-Summer encephalitis virus)

Variola virus

Venezuelan equine encephalitis virus

Western equine encephalitis virus

West Nile fever virus

Yellow fever virus

Viruses (affecting animals other than man)

African horse sickness virus

African swine fever virus

Bluetongue virus

Classical swine fever virus

Contagious bovine pleuropneumonia

Foot and mouth disease virus

Goat pox virus

Hendra virus (Equine morbillivirus)

Highly pathogenic avian influenza (HPAI) as defined in Annex I(2) of Council Directive 2005/94/EC

Lumpy skin disease virus

Newcastle disease virus

Peste des petits ruminants virus

Rift Valley fever virus

Rabies and rabies-related Lyssaviruses

Rinderpest virus

Sheep pox virus

Swine vesicular disease virus

Vesicular stomatitis virus


Coxiella burnetii

Rickettsia prowazeki

Rickettsia rickettsii

Rickettsia typhi (mooseri)


Bacillus anthracis

Brucella abortus

Brucella canis

Brucella melitensis

Brucella suis

Burkholderia mallei (Pseudomonas mallei)

Burkholderia pseudomallei (Pseudomonas pseudomallei)

Chlamydophila psittaci

Clostridium botulinum

Enterohaemorrhagic Escherichia coli, serotype 0157 and verotoxin producing strains

Francisella tularensis

Multiple-drug resistant Salmonella paratyphi

Salmonella typhi

Shigella boydii

Shigella dysenteriae

Shigella flexneri

Vibrio cholerae

Yersinia pestis



Botulinum toxins

Clostridium perfringens epsilon toxin Clostridium perfringens enterotoxin


Modeccin toxin



Shiga and shiga–like toxins

Staphylococcal enterotoxins


Viscum Album Lectin 1 (Viscumin)

Volkensin toxin