Testing a participant of a dementia study at Imperial College London's School of Public Health

What type of studies are being conducted?

Studies may vary from simple questionnaires to clinical trials investigating new preventative treatments. Those on the register will be given full details of each study and will have time to consider whether they would like to get involved. You are under no obligation to take part in any study just because you have agreed to be on the register.

Current Studies

The CHARIOT: PRO Substudy

An observational study examining changes in cognition over time, and how we can best identify these at an early stage. Involves medical health check, physical and neurological examinations and cognitive assessments.

Find out more: ChariotPro Substudy Summary Participant Information Sheet v2

The Generation 1 Study

Generation 1 is a study testing whether two new treatments are able to prevent or delay the onset of symptoms of Alzheimers disease. First there is a genetic pre-screening step, which you can read about here: 

Find out more: Generation 1 Prescreen - Participant Information Sheet V2

Previous research studies

Chariot PRO Main Study

An observational study examining changes in cognition over time, and how we can best identify these at an early stage. Involves medical health check, physical and neurological examinations and cognitive assessments.

The UK Prescreening Study

A study to assess memory function in individuals who feel they have noticed recent changes in their memory and to identify people interested in being involved in preventative trials.

Previous Studies

The TOMMORROW Study

An international clinical trial to determine whether a genetic biomarker can predict an individual’s risk of developing memory problems and determine whether a specific treatment would help delay the onset of memory problems in people who are at high risk.

Find out more: TOMMORROW Study Participant Information Sheet v8.0

MULTI-MODE Study

A pilot study to gather feedback on using a mobile phone app to receive a dementia risk score and guidance on how to lower this risk score.

Find out more: MULTI-MODE Pilot Study Participant Information Sheet

Volunteers who have consented to join the CHARIOT register are invited to participate in our research studies. Please visit our Get involved page to find out more.