MSc Genomic Medicine

A flexible, multi-disciplinary and multi-professional perspective in genomics applied to clinical practice and medical research.

Award titles

MSc

Duration: 1 year FT / 2 years PT
(including PG Cert and PG Dip)

Postgraduate Certificate

Duration: 4 months FT / 1 year PT
(standalone course)

Postgraduate Diploma

Duration: 8 months FT / 2 year PT
(including PG Cert)

Key information

Start date: October 2018
Campus
Various

Applications for 2018

Open to applications for 2018 entry
Register your interestApply now

Overview

Our degrees in Genomic Medicine cover all aspects of genomic science and medicine, and will equip you with the knowledge and skills to be able to interpret and understand genomic data that increasingly impacts on service delivery to patients and the community.

The programme is aimed at students from a wide range of backgrounds, from basic scientists to all levels of healthcare professionals, and will provide a flexible, multi-disciplinary and multi-professional perspective in genomics, applied to clinical practice and medical research.

It is designed to equip you with the knowledge and skills to be able to interpret and understand genomic data that increasingly impacts on service delivery to patients and the community.

The training provided covers all aspects of genomic science and medicine (not merely DNA sequencing or detection of genetic variation), undertaken in one of the most cutting-edge scientific environments. 

The course includes collaborations with:

  • the Institute of Cancer Research (providing the core Cancer Genomics Module)
  • Brunel University London (providing the optional Economic Evaluation in Human Genomics Module)

The Institute of Cancer Research and Brunel University London may also co-supervise research projects.

The programme is one of the preferred providers for Health Education England and upholds the values of the NHS Constitution.

Study programme

This course is made up of three progressional levels (PG Cert, PG Dip and MSc), and you can apply to any level in the first instance. Read more about how this works under 'Choosing your course' in the admissions section.

One of the core modules available within the Master's degree (MSc) includes opportunities to access the emerging data from the 100,000 Genomes Project through the Genomics England Clinical Interpretation Partnership (GeCIP) training domains.

Meet our students

Hear from Genomic Medicine students and graduates on the National Heart and Lung Institute website.

Structure

Modules shown are for the current academic year, and are subject to change depending on your year of entry.

As a preferred training provider for Higher Education England, this course plays an important role in ensuring NHS staff have the knowledge, skills and experience required to stay at the forefront of this essential field. The outcome of our bid for funding to continue supporting successful NHS applicants is expected in January 2018. If successful, we will be required to make some limited changes to the course content from September 2018 to ensure that our education continues to respond to the needs of modern healthcare practice.

We will continue interviewing applicants up to Christmas 2017. We will then begin making offers from February 2018 onwards when the outcome of the bid will be known. At this point, we will also let successful applicants know details of any planned changes so that they can decide whether the course is still right for them. If you have any questions about the impact of the changes, please contact the course administrator using the contact details below.

Structure

MSc

Core modules

You take all of the core modules listed below.

Core Concepts in Human Genetics and Genomics

Provides the basic genomic science knowledge required in later modules, including genomic architecture, regulatory systems, generic variation, function and how this impacts upon disease processes and clinical outcomes. Module Leader: Dr Louise Blakemore.

Application of Genomics in Infectious Disease

Explains how pathogen genomics inform the epidemiology of infections, impact drug development and resistance, lead to novel diagnostics/therapeutics/stratified healthcare, and provide insights into host susceptibilities to infection. Module Leader: Dr Fiona Culley.

Bioinformatics, Quality Control, Analysis and Interpretation of Genome Sequencing Data OR Genomics and the Patient

Bioinformatics – provides the principles of computational DNA sequence analysis, including sequence alignment methods and statistical tests, to identify and correctly communicate pathogenic mutations and assess possible functions through database and network programs. Module Leader: Professor Michael Lovett.

Genomics and the Patient – concentrates on the identification and interpretation of final Next–Generation DNA sequencing reports with an emphasis on calculating genetic risk and ethical considerations (less computationally intense). Module Leader: Dr Claire Shovlin.

Ethical, Legal and Social Issues in Applied Genomics

Explains the principles and subtleties of ethics in evaluating genetic/genomic data with an emphasis on emerging genomics technologies and the ways ethics issues are handled around the world. Module Leader: Prof Geraldine Thomas.

Genomics of Common and Rare Inherited Diseases

Explains the different types of genetic variation, their contribution to rare and complex disease, and how they are detected (with emphasis on the 100,000 Genomes Project), interpreted and communicated. Module Leaders: Dr Deborah Morris-Rosendahl and Dr Anna Need.

Molecular Pathology of Cancer and Application in Cancer Diagnosis, Screening and Treatment

Delivered by the Institute of Cancer Research. Explains the principles of cancer genomics, including predisposition, diagnosis, classification, treatment and patient monitoring with particular emphasis on how genomic analysis impacts these factors and ethical issues. Module Leader: Prof Ros Eeles.

Omics Technologies and their Application to Genomic Medicine

Provides an in–depth description of the genomic techniques that are used to assess genomic variation in clinical problems, allowing you to critically evaluate which techniques can be used and their limitations in analysing different disease states. Module Leader: Dr Inga Prokopenko.

Optional modules

You choose one module from below.

Economic Evaluation in Human Genomics

Dr Subhash Pokhrel. Delivered by Brunel University London. Explains the methods, assumptions, decision models, and interpretation of, cost estimate analysis, for health care interventions and health outcomes, with a particular emphasis on genomic medicine.

Genome Based Therapeutics

Covers key concepts in developing gene and nucleic acid-based therapies from genomic studies including efficacy and toxicity. Module Leader: Prof Uta Griesenbach.

Laboratory Skills for Genomics

A hands-on wet laboratory module which focuses on how to develop a good experimental design, carry out a genomic analysis project, identify and critically analyse sequence variants and determine the implications for patients. Module Leader: Professor Michael Lovett.

Pharmacogenomics and Stratified Medicine

Dr Letizia Foroni. Explains how genomic approaches can be used to understand the mechanisms of differential drug responses and reactions, and to inform patient stratification. An emphasis will be placed upon the current limitations and future prospects of pharmacogenomic studies.

Professional and Research Skills

An e-learning module. Teaches the differences between audit, research, qualitative, quantitative and systematic review methods, how to conduct literature searches, appraise published data, conduct appropriate statistical tests and understand the data management, ethical and reporting requirements in research studies, with a particular emphasis on the 100,000 Genomes Project and translational research. Module Leader: Dr Amir Hakim.

Research project

You complete a 14 week-full time or 1 year part-time research project as part of the MSc. We offer four types of project:

  • laboratory-based
  • clinical-based
  • computer-based
  • literature-based

Assessment is by written dissertation, oral presentation, viva and supervisor mark.

Research projects may be supervised at Imperial, or co-supervised at Imperial and the Institute of Cancer Research or Brunel University London. 

Postgraduate Certificate

Core module

You take the core module below.

Core Concepts in Human Genetics and Genomics

Provides the basic genomic science knowledge required in later modules, including genomic architecture, regulatory systems, generic variation, function and how this impacts upon disease processes and clinical outcomes. Module Leader: Dr Louise Blakemore.

Optional modules

You choose three optional modules from below, and may only include one module marked with an asterisk (*).

Application of Genomics in Infectious Disease

Explains how pathogen genomics inform the epidemiology of infections, impact drug development and resistance, lead to novel diagnostics/therapeutics/stratified healthcare, and provide insights into host susceptibilities to infection. Module Leader: Dr Fiona Culley.

Bioinformatics, Quality Control, Analysis and Interpretation of Genome Sequencing Data OR Genomics and the Patient

Bioinformatics – provides the principles of computational DNA sequence analysis, including sequence alignment methods and statistical tests, to identify and correctly communicate pathogenic mutations and assess possible functions through database and network programs. Module Leader: Professor Michael Lovett.

Genomics and the Patient – concentrates on the identification and interpretation of final Next–Generation DNA sequencing reports with an emphasis on calculating genetic risk and ethical considerations (less computationally intense). Module Leader: Dr Claire Shovlin.

Economic Evaluation in Human Genomics*

Delivered by Brunel University London. Explains the methods, assumptions, decision models, and interpretation of, cost estimate analysis, for health care interventions and health outcomes, with a particular emphasis on genomic medicine.

Ethical, Legal and Social Issues in Applied Genomics

Explains the principles and subtleties of ethics in evaluating genetic/genomic data with an emphasis on emerging genomics technologies and the ways ethics issues are handled around the world. Module Leader: Prof Geraldine Thomas.

Genome Based Therapeutics*

Covers key concepts in developing gene and nucleic acid-based therapies from genomic studies including efficacy and toxicity. Module Leader: Prof Uta Griesenbach.

Genomics of Common and Rare Inherited Diseases

Explains the different types of genetic variation, their contribution to rare and complex disease, and how they are detected (with emphasis on the 100,000 Genomes Project), interpreted and communicated. Module Leaders: Dr Deborah Morris-Rosendahl and Dr Anna Need.

Laboratory Skills for Genomics*

A hands-on wet laboratory module which focuses on how to develop a good experimental design, carry out a genomic analysis project, identify and critically analyse sequence variants and determine the implications for patients. Module Leader: Professor Michael Lovett.

Molecular Pathology of Cancer and Application in Cancer Diagnosis, Screening and Treatment

Delivered by the Institute of Cancer Research. Explains the principles of cancer genomics, including predisposition, diagnosis, classification, treatment and patient monitoring with particular emphasis on how genomic analysis impacts these factors and ethical issues. Module Leader: Prof Ros Eeles.

Omics Technologies and their Application to Genomic Medicine

Provides an in–depth description of the genomic techniques that are used to assess genomic variation in clinical problems, allowing you to critically evaluate which techniques can be used and their limitations in analysing different disease states. Module Leader: Dr Inga Prokopenko.

Pharmacogenomics and Stratified Medicine*

Explains how genomic approaches can be used to understand the mechanisms of differential drug responses and reactions, and to inform patient stratification. An emphasis will be placed upon the current limitations and future prospects of pharmacogenomic studies.

Professional and Research Skills*

An e-learning module. Teaches the differences between audit, research, qualitative, quantitative and systematic review methods, how to conduct literature searches, appraise published data, conduct appropriate statistical tests and understand the data management, ethical and reporting requirements in research studies, with a particular emphasis on the 100,000 Genomes Project and translational research. Module Leader: Dr Amir Hakim.

Postgraduate Diploma

Core modules

You take all of the core modules listed below.

Core Concepts in Human Genetics and Genomics

Provides the basic genomic science knowledge required in later modules, including genomic architecture, regulatory systems, generic variation, function and how this impacts upon disease processes and clinical outcomes. Module Leader: Dr Louise Blakemore.

Application of Genomics in Infectious Disease

Explains how pathogen genomics inform the epidemiology of infections, impact drug development and resistance, lead to novel diagnostics/therapeutics/stratified healthcare, and provide insights into host susceptibilities to infection. Module Leader: Dr Fiona Culley.

Bioinformatics, Quality Control, Analysis and Interpretation of Genome Sequencing Data OR Genomics and the Patient

Bioinformatics – provides the principles of computational DNA sequence analysis, including sequence alignment methods and statistical tests, to identify and correctly communicate pathogenic mutations and assess possible functions through database and network programs. Module Leader: Professor Michael Lovett.

Genomics and the Patient – concentrates on the identification and interpretation of final Next–Generation DNA sequencing reports with an emphasis on calculating genetic risk and ethical considerations (less computationally intense). Module Leader: Dr Claire Shovlin.

Ethical, Legal and Social Issues in Applied Genomics

Explains the principles and subtleties of ethics in evaluating genetic/genomic data with an emphasis on emerging genomics technologies and the ways ethics issues are handled around the world. Module Leader: Prof Geraldine Thomas.

Genomics of Common and Rare Inherited Diseases

Explains the different types of genetic variation, their contribution to rare and complex disease, and how they are detected (with emphasis on the 100,000 Genomes Project), interpreted and communicated. Module Leaders: Dr Deborah Morris-Rosendahl and Dr Anna Need.

Molecular Pathology of Cancer and Application in Cancer Diagnosis, Screening and Treatment

Delivered by the Institute of Cancer Research. Explains the principles of cancer genomics, including predisposition, diagnosis, classification, treatment and patient monitoring with particular emphasis on how genomic analysis impacts these factors and ethical issues. Module Leader: Prof Ros Eeles.

Omics Technologies and their Application to Genomic Medicine

Provides an in–depth description of the genomic techniques that are used to assess genomic variation in clinical problems, allowing you to critically evaluate which techniques can be used and their limitations in analysing different disease states. Module Leader: Dr Inga Prokopenko.

Optional modules

You choose one module from below.

Economic Evaluation in Human Genomics

Delivered by Brunel University London. Explains the methods, assumptions, decision models, and interpretation of, cost estimate analysis, for health care interventions and health outcomes, with a particular emphasis on genomic medicine.

Genome Based Therapeutics

Covers key concepts in developing gene and nucleic acid-based therapies from genomic studies including efficacy and toxicity. Module Leader: Prof Uta Griesenbach.

Laboratory Skills for Genomics

A hands-on wet laboratory module which focuses on how to develop a good experimental design, carry out a genomic analysis project, identify and critically analyse sequence variants and determine the implications for patients. Module Leader: Professor Michael Lovett.

Pharmacogenomics and Stratified Medicine

Explains how genomic approaches can be used to understand the mechanisms of differential drug responses and reactions, and to inform patient stratification. An emphasis will be placed upon the current limitations and future prospects of pharmacogenomic studies.

Professional and Research Skills

An e-learning module. Teaches the differences between audit, research, qualitative, quantitative and systematic review methods, how to conduct literature searches, appraise published data, conduct appropriate statistical tests and understand the data management, ethical and reporting requirements in research studies, with a particular emphasis on the 100,000 Genomes Project and translational research. Module Leader: Dr Amir Hakim.

Teaching and assessment

Teaching methods

  • Computer lab teaching
  • Data analysis sessions
  • Debates
  • Discussion sessions
  • Interactive content including video and module quizzes
  • Journal clubs
  • Keynote lectures
  • Laboratory teaching
  • Lectures
  • On-line discussion forums
  • On-line lecture materials
  • Problem-based group work
  • Seminars

Assessment methods

  • Coursework
  • Examination
  • Practical
  • Research project (MSc only)

Course timetable

A blended approach to learning is used, in both core and optional modules, combining face-to-face teaching and online distance learning. This is to provide flexibility for health professionals to combine their study with work.

Most modules will consist of one week of face-to-face teaching and up to three weeks of e-learning and independent study. The modules are offered on a cycle of 12 months, so that all modules become available once in each 12 month cycle.

The course is flexible and modular and is available as a full-time or part-time MSc delivered over one or two years respectively. There are also full-time and part-time Postgraduate Certificate (PG Cert) and Postgraduate Diploma (PG Dip) options.

Tuition fees and funding

The level of tuition fees you pay is based on your fee status, which we assess based on UK government legislation.

For more information on the funding opportunities that are available, please visit our Fees and Funding website.

Tuition fees and funding

Tuition fees (Home and EU students)

2018 entry
Postgraduate Certificate £4,000
Postgraduate Diploma £4,000
MSc £4,000
Tuition fees are listed separately, please read the following text.

This course is divided into three progressional levels of study. Each level results in three separate qualifications (PG Cert, PG Dip and MSc). The tuition fees listed above apply separately to each qualification.

Except where otherwise indicated, the fees for students on courses lasting more than one year will increase annually by an amount linked to inflation, including for part-time students on modular programmes. The measure of inflation used will be the Retail Price Index (RPI) value in the April of the calendar year in which the academic session starts e.g. the RPI value in April 2019 will apply to fees for the academic year 2019–2020.

If you apply to the PG Dip or MSc, please note that you will study the previous levels of the course if you have not already done so. You should therefore add up the tuition fees (i.e. PG Dip fee is the PG Cert fee plus the PG Dip fee). Any payments made in subsequent academic years will have an inflationary increase applied (as described above), but only to the outstanding balance for that year.

Please note, you can’t get a Postgraduate loan from the UK government for a Postgraduate Certificate or Diploma, only the MSc is eligible.

Tuition fees (Overseas and Islands students)

2018 entry
Postgraduate Certificate £16,250
Postgraduate Diploma £9,750
MSc £6,500
Tuition fees are listed separately, please read the following text.

This course is divided into three progressional levels of study. Each level results in three separate qualifications (PG Cert, PG Dip and MSc). The tuition fees listed above apply separately to each qualification.

Except where otherwise indicated, the fees for students on courses lasting more than one year will increase annually by an amount linked to inflation, including for part-time students on modular programmes. The measure of inflation used will be the Retail Price Index (RPI) value in the April of the calendar year in which the academic session starts e.g. the RPI value in April 2019 will apply to fees for the academic year 2019–2020.

If you apply to the PG Dip or MSc, please note that you will study the previous levels of the course if you have not already done so. You should therefore add up the tuition fees (i.e. PG Dip fee is the PG Cert fee plus the PG Dip fee). Any payments made in subsequent academic years will have an inflationary increase applied (as described above), but only to the outstanding balance for that year.

Please note, you can’t get a Postgraduate loan from the UK government for a Postgraduate Certificate or Diploma, only the MSc is eligible.

Postgraduate Master's loan

If you are a Home or EU student who meets certain criteria, you may be able to apply for a Postgraduate Master’s Loan of up to £10,280 from the UK government. The loan is not means-tested, and you can choose whether to put it towards your tuition fees or living costs.

You must apply for the MSc in this course in order to be eligible for a Postgraduate Master's Loan.

Scholarships

We offer a range of scholarships for postgraduate students to support you through your studies. Try our scholarships search tool to see what you might be eligible for.

There are a number of external organisations also offer awards for Imperial students, find out more about non-Imperial scholarships.

Accommodation and living costs

Living costs, including accommodation, are not included in your tuition fees.

You can compare costs across our different accommodation options on our Accommodation website.

A rough guide to what you might expect to spend to live in reasonable comfort in London is available on our Fees and Funding website.

Admissions

We welcome students from all over the world and consider all applicants on an individual basis.

For advice on the requirements for the qualifications listed here please contact the Department (details at the bottom of this page).

We also accept a wide range of international qualifications. If the requirements for your qualifications are not listed here, please see our academic requirements by country page for guidance on which qualifications we accept.

Admissions

Minimum academic requirement

Our minimum requirement is at least a 2.1 UK Honour's degree (or equivalent) in a relevant medical, biomedical or healthcare subject.

In special cases students may be admitted to this course with high-quality work experience in place of the above requirement.

International qualifications

The academic requirement above is for applicants who hold or who are working towards a UK qualification. 

We also accept a wide variety of international qualifications. For guidance see our Country Index though please note that the standards listed here are the minimum for entry to the College.

If you have any questions about admissions and the standard required for the qualification you hold or are currently studying then please contact the relevant admissions team.

English language requirement (all applicants)

All candidates must demonstrate a minimum level of English language proficiency for admission to the College.

For admission to this course, you must achieve the standard College requirement in the appropriate English language qualification. For details of the minimum grades required to achieve this requirement, please see the English language requirements for postgraduate applicants.

Choosing your course

This course is divided into three progressional levels of study:

  • PG Certificate (PG Cert)
  • PG Diploma (PG Dip)
  • MSc

Each level of study has its own separate entry point; you can apply to any level in the first instance.

Depending on the level of study you choose, you may complete more than one qualification simultaneously. For example:

  • If you enter at the PG Cert level, as this is the first level of study, you can choose to exit the course at the completion of your studies with only this qualification.
  • If you enter the course at the PG Dip level, you will complete the PG Cert as part of your studies, though will graduate with one award (PG Dip).
  • If you enter at MSc level, you will complete the PG Cert and PG Dip as part of your studies though, as above, will graduate with one award (MSc).

If you have already graduated from one level of study for this course and re-enter the next level of study following a break, you will not have to repeat studies relating to the qualification that you have already gained e.g. if you have a PG Cert, you can complete the PG Dip without repeating the content related to the PG Cert.

How to apply

All applicants must apply online.

You can usually apply for up to two courses, although your second choice will only be considered if your first-choice application is unsuccessful.

Although courses will remain open until they are filled, applicants for this course are strongly encouraged to apply by 1 August 2018. Early applications allow us to communicate important information around key dates with applicants directly.

If you need a visa to study in the UK, we advise that you apply by 1 July 2018 to ensure that your visa is processed and approved prior to the start of the course.

You will need to upload documents with your applications, which may include transcripts and degree certificates.

Offer holders will need to pay a deposit to secure your place. This will be deducted from the balance of your tuition fees.

For full details on the online application process, or to start your application, please visit the How to Apply section of our website.

ATAS certificate

An ATAS certificate is not required for overseas students applying for this course.

Contact us

Microbiome

Got a question?

Enquiries
Eleanor Wilde, Course Administrator
T: +44 (0)20 7594 7767
E: genomic@imperial.ac.uk

Read more about the NHLI and our research on the National Heart and Lung Institute website.

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