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Synthetic Biology underpins advances in the bioeconomy

Biological systems - including the simplest cells - exhibit a broad range of functions to thrive in their environment. Research in the Imperial College Centre for Synthetic Biology is focused on the possibility of engineering the underlying biochemical processes to solve many of the challenges facing society, from healthcare to sustainable energy. In particular, we model, analyse, design and build biological and biochemical systems in living cells and/or in cell extracts, both exploring and enhancing the engineering potential of biology. 

As part of our research we develop novel methods to accelerate the celebrated Design-Build-Test-Learn synthetic biology cycle. As such research in the Centre for Synthetic Biology highly multi- and interdisciplinary covering computational modelling and machine learning approaches; automated platform development and genetic circuit engineering ; multi-cellular and multi-organismal interactions, including gene drive and genome engineering; metabolic engineering; in vitro/cell-free synthetic biology; engineered phages and directed evolution; and biomimetics, biomaterials and biological engineering.

Publications

Citation

BibTex format

@article{Meng:2020:10.1038/s41467-020-19092-2,
author = {Meng, F and Ellis, T},
doi = {10.1038/s41467-020-19092-2},
journal = {Nature Communications},
pages = {5174--5174},
title = {The second decade of synthetic biology: 2010-2020.},
url = {http://dx.doi.org/10.1038/s41467-020-19092-2},
volume = {11},
year = {2020}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Synthetic biology is among the most hyped research topics this century, and in2010 it entered its teenage years. But rather than these being a problematictime, we’ve seen synthetic biology blossom and deliver many new technologiesand landmark achievements.
AU - Meng,F
AU - Ellis,T
DO - 10.1038/s41467-020-19092-2
EP - 5174
PY - 2020///
SN - 2041-1723
SP - 5174
TI - The second decade of synthetic biology: 2010-2020.
T2 - Nature Communications
UR - http://dx.doi.org/10.1038/s41467-020-19092-2
UR - https://www.ncbi.nlm.nih.gov/pubmed/33057059
UR - http://hdl.handle.net/10044/1/84346
VL - 11
ER -

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Work in the IC-CSynB is supported by a wide range of Research Councils, Learned Societies, Charities and more.