Group
The group is highly multidisciplinary, with researchers working on synthesis and structural biology, proteomics and cell biology, on in vitro and in vivo systems, often undertaking work in collaboration with labs at Imperial in Medicine, Engineering and Natural Sciences, and groups at institutes and companies across the UK and worldwide. Group membership is also highly diverse - more than 145 researchers have worked in our group over the years, encompassing 28 nationalities.
Staff
Dr Anna Barnard
Dr Anna Barnard
Imperial College Junior Research Fellow
Dr Marc Baggelaar
Dr Marc Baggelaar
Marie Curie Research Fellow in chemical biology
Dr Andy Bell
Dr Andy Bell
MRC/MMV research associate, medicinal chemistry (5, 6)
Dr Chiara Fabbro
Dr Chiara Fabbro
Marie Sklodowska-Curie Research Fellow in Chemical Biology
Dr Monica Faronato
Dr Monica Faronato
CRUK research associate in cancer cell & chemical biology
Dr Aurélien Godinat
Dr Aurélien Godinat
SNSF Fellow in chemical biology
Kate Hadavizadeh
Kate Hadavizadeh
Research Assistant - Chemical proteomic target ID
Dr Jennie Hutton
Dr Jennie Hutton
Research associate and lab manager, drug discovery and development
Dr Wouter Kallemeijn
Dr Wouter Kallemeijn
Newton International Fellow - roles of protein lipidation in trafficking and secretion
Dr Tom Lanyon-Hogg
Dr Tom Lanyon-Hogg
CRUK research associate in structural & chemical biology, (13, 14)
Scott Lovell
Scott Lovell
MRC Research Assistant - novel chemical proteomic probes, and their applications in disease
Dr Anna Neodo
Dr Anna Neodo
SNSF Fellow - new chemical probes for the KLK activome
Dr Tony Ocasio
Dr Tony Ocasio
Senior Laboratory Research Scientist at The Francis Crick Institute
Dr Inma Perez Dorado
Dr Inma Perez Dorado
Medicines for Malaria Venture research associate in structural biology (13, 5)
Dr Markus Ritzefeld
Dr Markus Ritzefeld
Medicines for Malaria Venture research associate (3, 5)
Dr Fiona Rowan
Dr Fiona Rowan
Academy of Medical Sciences research associate, PPI inhibitors, with Anna Barnard (29)
Dr Masha Shchepinova
Dr Masha Shchepinova
BBSRC research associate in GPCR chemical biology (34-36)
Dr Charlotte Sutherell
Dr Charlotte Sutherell
CRUK research associate in drug discovery and chemical biology (13, 14)
PhD students
Sharlin Patel
Sharlin Patel
4th year PhD student. Chemical proteomics, fatty acid elongation (10, 18)
Jessica Shen
Jessica Shen
4th year PhD/Lee Family Scholar. Drug discovery against protein lipid transferases
Foteini Tzakoniati
Foteini Tzakoniati
4th year ICB BBSRC PhD student. Chemical probes for NaV channels (4, 40)
Wenye Zhao
Wenye Zhao
4th year PhD /Imperial Scholar. Protein modification during cell death (13,14)
Greg Craven
Greg Craven
3rd year ICB CDT PhD, kinetic covalent fragment-based inhibitor discovery (12, 17)
Roman Fedoryshchak
Roman Fedoryshchak
3rd year Marie Curie IDP PhD, chemical biology and antifungals (18)
Kate Hadavizadeh
Kate Hadavizadeh
3rd year ICB CASE PhD student. Chemical proteomic target ID (21)
Scott Lovell
Scott Lovell
3rd year ICB PhD student. Chemical proteomics and modelling of the KLK activome (16)
Mostafa Jamshidiha
Mostafa Jamshidiha
3rd year PhD student. Structure-guided inhibitor design for protein interfaces (13,14)
Jim Squires
Jim Squires
3rd year ICB PhD student. Single-cell chemical proteomics (15)
Mladen Stojanovic
Mladen Stojanovic
3rd year Marie Curie IDP PhD, chemical proteomics and insecticides (18)
Theo Flack
Theo Flack
2nd year ICB CDT PhD student, with Anna Barnard (29, 13, 22)
Will Joyce
Will Joyce
ICB 2nd year PhD student. Chemical biological control of flowering (10, 22)
Shao-Ju (Ryan) Lu
Shao-Ju (Ryan) Lu
3rd year ICB PhD, optical proteomics (19, 20)
Eloise Morecroft
Eloise Morecroft
2nd year ICB CDT MRes/PhD student. Reversing resistance in ovarian cancer (24-26)
Gregor Lueg
Gregor Lueg
2nd year Crick/Imperial CDT PhD. Mode of action of protein lipidation inhibitors in cancer (28)
Nattawadee Panyain
Nattawadee Panyain
2nd year ICB CDT PhD student. Royal Thai Scholar, chemical biology, protein prenylation
Charlie Saunders
Charlie Saunders
2nd year ICB CDT PhD student. Chemical tools targeting malaria parasite molecular motors (23,13)
Anja Schlott
Anja Schlott
2nd year Crick/Imperial CDT PhD. Mode of action of protein lipidation inhibitors in malaria (24)
Jasmine Bickel
Jasmine Bickel
1st year ICB CDT PhD student. Chemical biology of the membrane attack complex (29, 30)
Chiara Cecconello
Chiara Cecconello
ICB CDT/Nestle MRes/PhD. GPCRs in appetite regulation (34-36)
Andrea Goya Grocin
Andrea Goya Grocin
1st year CRUK PhD student, protein lipidation in cancer
Miha Homsak
Miha Homsak
1st year Crick/Imperial joint CDT PhD. Protein lipidation as a target in tuberculosis (38)
Ryan Howard
Ryan Howard
ICB CDT/AstraZeneca MRes/PhD. Centrosome declustering in cancer (19, 28, 37)
Cassandra Kennedy
Cassandra Kennedy
ICB CDT MRes/PhD. Protein lipidation in inflammation & infection (8, 39)
Masters and UG students
Rania Al Janabi
Rania Al Janabi
MRes Drug Discovery, anticancer drug discovery (13, 14)
Daniel Fernandez Llaneza
Daniel Fernandez Llaneza
MRes Drug Discovery, novel antileishmanial agents (41)
Rian Hendley
Rian Hendley
MSci project student, novel Rab27a inhibitors (13, 14, 24)
Isabella Kaczmarczyk
Isabella Kaczmarczyk
MRes Drug Discovery, E3 ligase probes in inflammation (39)
Ana Losada De La Lastra
Ana Losada De La Lastra
UROP placement student
Dongxun Lyu
Dongxun Lyu
UROP placement student
Sebastian Oehler
Sebastian Oehler
MRes Drug Discovery, target ID for antileishmanial agents (41, 42)
Carine Lim
Carine Lim
MRes Drug Discovery, AddAB and RecBCD inhibitors (43, 44)
Yumeng Sun
Yumeng Sun
IROP placement student
Yingchao Wang
Yingchao Wang
MRes Drug Discovery, helix mimetics, with Anna Barnard (29)
Leran Zhang
Leran Zhang
MRes Drug Discovery, novel Hhat inhibitors targeting cancer (3)
Associated with our group
Dara Annett
Dara Annett
PhD student, Francis Crick Institute, drug target discovery in malaria parasites
James Duncan
James Duncan
MRes Drug Discovery med chem cohort, with Armstrong, Evans, Wigneshweraraj
Daniel Miles
Daniel Miles
MRes Drug Discovery med chem cohort, with Matt Fuchter and Anna Barnard
Christelle Soudy
Christelle Soudy
Senior Research Scientist at the Francis Crick Institute (synthetic organic chemistry)
Amaia Uriz
Amaia Uriz
MRes Drug Discovery med chem cohort, with Matt Fuchter
Alumni
Postdoctoral Researchers: Sasala Wickramasinghe (2008), Lucia de la Riva Perez (2010), Dmitry Stetsenko (2011), Vicki Barker (2011), Matt Selby (2011), Ute Brassat (2011), Will Heal (2012), Victor Goncalves (2012), Victoria Albrow (2013), Mark Rackham (2013), Zhiyong Yu (2013), Antonio Konitsiotis (2014), Jennie Hutton (2014), Goska Broncel (2015), Soo Mei Chee (2015), Kalesh (2015), Rhiannon Beard (2017), Julia Morales Sanfrutos (2017)
PhD Students: Panumart Thongyoo (2009), Gillian Rosenberg (2010), Jemima Thomas (2011), Tam Dang (2011), Tayo Olaleye (2012), Lucy Rayner (2012), Alex Berry (2012), Jenny Frueh (2012), Megan Wright (2013), Manue Thinon (2013), Chris Douse (2014), Naoko Masumoto (2015), Paulina Ciepla (2015), Tom Charlton (2015), James Clulow (2015), Andy Bell (2015), Louis Perdios (2016), Siak Lim (2016), Lisa Storck Saha (2016), Rhiannon Beard (2016) Ernie So (2016), Yunyun Sun (2017)
MRes students: 2008: Pinar Tulay, Martyna Snopek, Kavita Ramji. 2009: Antoine Delmotte. 2010: Kim Williams, Lucy Esteve, Janet Tsang. 2011: Dani Monteil. 2012: Tiffany Teng, Nino Gaphrindashivili. 2013: Liji Huang, George Bodakh, June Lim, Xiaoyi Wang, Eric Lee. 2014: Yuchen Zhao. 2015: Larissa See, Runzhong Fu, Jason Mak, Sandi Botonjic, Giovanna Morsiani. 2016: Juan Cuadrado, Lerui Guo, Zuzana Hodakova, Miriam Lyons, Niall McLoughlin, Sebastian Soh, Congyi Xu, Handa Zhang.
Undergraduate project/placement students: 2006: Helen Mcleod. 2007: Will Tomlinson, Katherine Elvira, Camille Bonomelli. 2008: James Sudlow. 2009: Irvine Howson, Vlad Turek, Sara Bessin. 2010: Aled Williams, Amanda Cheung, Sascha Yousefi, Genshi Chen. 2011: Machi Panteli, Brian Wilson, Timo Voelker, Wenlin Zhang, Nina Vrielink, Julia Gonzales Hernandes, Sibyl Sheppard. 2012: Enrico Fantoni, Jenny Mizen, Solene Batut, Klaudia Cybulska, Boon Kiat Lee. 2013: Wai Peng Leong, Alice Huynh, Ben Chappell, Sabrina Maas, Chrystalla Constantinou, Will Whitehurst, Saphia Matthew. 2014: Olivia Boyd, James Davies, Xavier Wezen, Shuang Liu, Wouter Mooij, Niall McLoughlin. 2015: Tiffany Chan, Shuang Liu, Markus Artelsmair, Joel Fauser. 2016: Yuen Chow, Michelle Tan, Jenny Samphire, Suk Tan, Annina Burhop, Edward Ou, Alex Bakker, Christine Wu. 2017: Aditya Raymond Thawani, Rhian Hendley
Visiting researchers: Dr Kasia Blewska (Lodz, COST network, 2015), Dany Pechalrieu (Toulouse, COST network, 2015), Daniela Glatzova (University of Prague, RSC mobility award, 2016).
Collaborating labs and organisations
1. Peter O’Hare (Virology); 2. The Francis Crick Institute; 3. Tony Magee (NHLI); 4. Pfizer Neusentis; 5. Medicines for Malaria Venture; 6. Imperial Innovations; 7. Matilda Katan (UCL), Paul French (Laser Physics); 8. Beata Wojciak-Stothard (Medicine); 9. Gad Frankel (Molecular Microbiology); 10. Tony Gee (KCL); 11. Colin Turnbull (Plant Physiology); 12. David Mann (Life Sciences); 13. Ernesto Cota (Structural Biology); 14. Institute of Cancer Research; 15. David Klug (Chemistry); 16. Reiko Tanaka (Bioengineering); 17. Syngenta; 18. Alan Armstrong (Chemistry); 19. AstraZeneca; 20. David Klug (Chemistry); 21. Oscar Ces (Chemistry); 22. Jake Baum (Parasitology); 23. Xiaodong Zhang (Structural Biology); 24. Chiara Recchi (Oncology); 25. Keith Willison (Chemistry); 26. Hani Gabra (Oncology); 27. Tony Holder (Crick); 28. Dinis Calado (Crick); 29. Anna Barnard (Chemistry); 30. Doryen Bubeck (Structural Biology); 31. Charlotte Dodson (Biophysics); 32. Edgar Deu (Crick); 33. Alex Lyons (Medicine, NHLI); 34. Gary Frost (Medicine); 35. Aylin Hanyaloglu (Medicine); 36. Nestle; 37. Susana Godinho (The Barts Cancer Institute, London); 38. Luiz Pedro Carvalho (Crick); 39. Avinash Shenoy (Microbiology); 40. Genentech.