Collage of published research papers

Citation

BibTex format

@article{Zimmerman:2021:10.1016/j.jbiomech.2021.110256,
author = {Zimmerman, K and Kim, J and Karton, C and Lochhead, L and Sharp, D and Hoshizaki, T and Ghajari, M},
doi = {10.1016/j.jbiomech.2021.110256},
journal = {Journal of Biomechanics},
title = {Player position in American Football influences the magnitude of mechanical strains produced in the location of chronic traumatic encephalopathy pathology: a computational modelling study},
url = {http://dx.doi.org/10.1016/j.jbiomech.2021.110256},
volume = {118},
year = {2021}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - American football players are frequently exposed to head impacts, which can cause concussions and may lead to neurodegenerative diseases such as chronic traumatic encephalopathy (CTE). Player position appears to influence the risk of concussion but there is limited work on its effect on the risk of CTE. Computational modelling has shown that large brain deformations during head impacts co-localise with CTE pathology in sulci. Here we test whether player position has an effect on brain deformation within the sulci, a possible biomechanical trigger for CTE. We physically reconstructed 148 head impact events from video footage of American Football games. Players were separated into 3 different position profiles based on the magnitude and frequency of impacts. A detailed finite element model of TBI was then used to predict Green-Lagrange strain and strain rate across the brain and in sulci. Using a one-way ANOVA, we found that in positions where players were exposed to large magnitude and low frequency impacts (e.g. defensive back and wide receiver), strain and strain rate across the brain and in sulci were highest. We also found that rotational head motion is a key determinant in producing large strains and strain rates in the sulci. Our results suggest that player position has a significant effect on impact kinematics, influencing the magnitude of deformations within sulci, which spatially corresponds to where CTE pathology is observed. This work can inform future studies investigating different player-position risks for concussion and CTE and guide design of prevention systems.
AU - Zimmerman,K
AU - Kim,J
AU - Karton,C
AU - Lochhead,L
AU - Sharp,D
AU - Hoshizaki,T
AU - Ghajari,M
DO - 10.1016/j.jbiomech.2021.110256
PY - 2021///
SN - 0021-9290
TI - Player position in American Football influences the magnitude of mechanical strains produced in the location of chronic traumatic encephalopathy pathology: a computational modelling study
T2 - Journal of Biomechanics
UR - http://dx.doi.org/10.1016/j.jbiomech.2021.110256
UR - https://www.sciencedirect.com/science/article/pii/S0021929021000361?via%3Dihub
UR - http://hdl.handle.net/10044/1/86943
VL - 118
ER -

Awards

  • Finalist: Best Paper - IEEE Transactions on Mechatronics (awarded June 2021)

  • Finalist: IEEE Transactions on Mechatronics; 1 of 5 finalists for Best Paper in Journal

  • Winner: UK Institute of Mechanical Engineers (IMECHE) Healthcare Technologies Early Career Award (awarded June 2021): Awarded to Maria Lima (UKDRI CR&T PhD candidate)

  • Winner: Sony Start-up Acceleration Program (awarded May 2021): Spinout company Serg Tech awarded (1 of 4 companies in all of Europe) a place in Sony corporation start-up boot camp

  • “An Extended Complementary Filter for Full-Body MARG Orientation Estimation” (CR&T authors: S Wilson, R Vaidyanathan)

UK DRI


Established in 2017 by its principal funder the Medical Research Council, in partnership with Alzheimer's Society and Alzheimer’s Research UK, The UK Dementia Research Institute (UK DRI) is the UK’s leading biomedical research institute dedicated to neurodegenerative diseases.