Citation data:

  • Articles: 108
  • h-index: 33
  • Citations: 2981
  • Citations per paper: 28

View this Publons page for more information. Some of the cover featuring our work are shown below:

Publications

 


Chapters:

Wilton-Ely J, 2006, Dinuclear ruthenium and osmium compounds with metal-metal bonds, Comprehensive Organometallic Chemistry III, Editor(s): Crabtree, Mingos, Elsevier, Pages:647-716, ISBN:978-0080445908


Journal Articles:

Citation

BibTex format

@article{Chabloz:2020:10.1002/chem.201904757,
author = {Chabloz, N and Perry, H and Yoon, I-C and Coulson, A and White, A and Stasiuk, G and Botnar, R and Wilton-Ely, J},
doi = {10.1002/chem.201904757},
journal = {Chemistry – A European Journal},
pages = {4552--4566},
title = {Combined magnetic resonance imaging and photodynamic therapy using polyfunctionalised nanoparticles bearing robust gadolinium surface units},
url = {http://dx.doi.org/10.1002/chem.201904757},
volume = {26},
year = {2020}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - A robust dithiocarbamate tether allows novel gadolinium units based on DOTAGA (q = 1) to be attached to the surface of gold nanoparticles (2.6 4.1 nm diameter) along with functional units offering biocompatibility, targeting and photodynamic therapy. A dramatic increase in relaxivity (r1) per Gd unit from 5.01 mM−1 s−1 in unbound form to 31.68 mM−1 s−1 (10 MHz, 37 °C) is observed when immobilised on the surface due to restricted rotation and enhanced rigidity of the Gd complex on the nanoparticle surface. The singlestep synthetic route provides a straightforward and versatile way of preparing multifunctional gold nanoparticles, including examples with conjugated zinctetraphenylporphyrin photosensitizers. The lack of toxicity of these materials (MTT assays) is transformed on irradiation of HeLa cells for 30 minutes (PDT), leading to 75% cell death. In addition to passive targeting, the inclusion of units capable of actively targeting overexpressed folate receptors illustrates the potential of these assemblies as targeted theranostic agents.
AU - Chabloz,N
AU - Perry,H
AU - Yoon,I-C
AU - Coulson,A
AU - White,A
AU - Stasiuk,G
AU - Botnar,R
AU - Wilton-Ely,J
DO - 10.1002/chem.201904757
EP - 4566
PY - 2020///
SN - 0947-6539
SP - 4552
TI - Combined magnetic resonance imaging and photodynamic therapy using polyfunctionalised nanoparticles bearing robust gadolinium surface units
T2 - Chemistry – A European Journal
UR - http://dx.doi.org/10.1002/chem.201904757
UR - https://onlinelibrary.wiley.com/doi/abs/10.1002/chem.201904757
UR - http://hdl.handle.net/10044/1/76438
VL - 26
ER -