@article{Szostak:2017:10.3389/fnins.2017.00665,
author = {Szostak, K and Grand, L and Constandinou, TG},
doi = {10.3389/fnins.2017.00665},
journal = {Frontiers in Neuroscience},
title = {Neural interfaces for intracortical recording: requirements, fabrication methods, and characteristics},
url = {http://dx.doi.org/10.3389/fnins.2017.00665},
volume = {11},
year = {2017}
}

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TY  - JOUR
AB  - Implantable neural interfaces for central nervous system research have been designed with wire, polymer or micromachining technologies over the past 70 years. Research on biocompatible materials, ideal probe shapes and insertion methods has resulted in building more and more capable neural interfaces. Although the trend is promising, the long-term reliability of such devices has not yet met the required criteria for chronic human application. The performance of neural interfaces in chronic settings often degrades due to foreign body response to the implant that is initiated by the surgical procedure, and related to the probe structure, and material properties used in fabricating the neural interface. In this review, we identify the key requirements for neural interfaces for intracortical recording, describe the three different types of probes- microwire, micromachined and polymer-based probes; their materials, fabrication methods, and discuss their characteristics and related challenges.
AU  - Szostak,K
AU  - Grand,L
AU  - Constandinou,TG
DO  - 10.3389/fnins.2017.00665
PY  - 2017///
SN  - 1662-4548
TI  - Neural interfaces for intracortical recording: requirements, fabrication methods, and characteristics
T2  - Frontiers in Neuroscience
UR  - http://dx.doi.org/10.3389/fnins.2017.00665
UR  - http://www.frontiersin.org/
UR  - http://hdl.handle.net/10044/1/53632
VL  - 11
ER  - 

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