Biomedical Instrumentation

Module aims

This module will develop and shape the students’ ability to translate a set of bioengineering/biomedical specifications into a practical and robust instrumentation architecture.

Learning outcomes

Describe and explain the operation and limitations of a library of linear and non-linear signal conditioning circuits (e.g. HWR, FWR, detectors, diff. amplifiers, instrumentation amplifiers, filters etc.); Explain how individual block choices and limitations affect system-level performance; Comment on the role of noise in a practical system; Analyse, dissect and solve a basic instrumentation problem by proposing a practical system-level architecture with appropriately tailored building blocks whose limitations are well-understood; Suggest how building-block non-idealities affect system level performance; Assemble an instrument prototype; Debug a prototype board; Use measuring equipment effectively.

Module syllabus

Non-idealities of Op-Amps; Filters: theory, op-amp-based active-RC filter realisation, first-order filters and their properties, second-order filters and their properties, higher-order filters and their properties; Linear Circuits for instrumentation: differential amplifiers and conditions for optimal performance, instrumentation amplifiers and applications, bridge amplifiers; Non-linear Circuits for instrumentation: half-wave-rectifier, full-wave-rectifier, peak-detector, voltage-level detector with independent adjustment of hysteresis & centre voltage; comparators: application to ECG, AC-DC converters; log-antilog amplifiers; Noise: its nature and properties; basic calculations; noise of electronic components; linearity assessment of a gain stage and concept of distortion; dynamic range.


BE1-HEE1 Electrical Engineering 1 BE1-HEBP Electronic Build Project BE1-HVAW Vibrations and Waves BE2-HEE2 - Electrical Engineering II

Teaching methods

Lectures: 10 hours
Labs: 20 hours



Written exam: worth 50%, Open Book

Exam rubric: One design question. Open book exam. 75 min duration.


Item 1: Written report Title: Impedometric Respirometer Lab Report Description: lab report; Weighting: 50 %

Outline answers to past papers will be available

Feedback : Written comments on the hardcopy of submitted Lab Report (worth 50% of the mark).

Reading list


Module leaders

Professor Emm Mic Drakakis