Molecular Bioengineering (MEng)
Tissue Engineering and Regenerative Medicine (UG)
This course will introduce you to the fundamental concepts of normal tissue development and how researchers have used this information to imitate nature in a lab setting, engineering cells and tissues that may be used to model diseases, treat disease, or develop drugs.
Knowledge and Understanding
- To define cell building blocks, and be able to explain how these building blocks are composed to make cells with different functions
- To recognise how single amino acid changes can alter protein, and subsequently cell function.
- To understand why different cell types are required in different tissues.
- To recall methods for generating induced pluripotent stem cells.
- To describe stem cell differentiation techniques, and identify how these protocols were developed (imitating nature).
- To be able to express where cell and tissue therapy are beneficial.
- To discuss the implications of gene therapy.
- To describe how tissue engineering can be beneficial in drug development.
Be able to propose tissue engineering solutions for different diseases.
Be capable of designing experimental protocols, and knowing the plan of action if a blood sample, or tissue biopsy is sent to the lab for a particular disease.
Learning: make course notes, research and review literature.
Cell building blocks: How do cells take a DNA code to make proteins? Amino acid structure and charge. INDELS and SNPS and their impact on protein structures.
BE1-HCMP Molecules, cells and processes BE1-HMS1 Medical Science 1 BE2-HMS2 Medical Science 2
Students will be taught over one term using a combination of lectures and study groups. Lecture sessions will be made available on Panopto for review and supplemented with technologies as appropriate to promote active engagement during the lecture such as 'learning catalytics'. Study groups will be based on taught content from lectures to reinforce these topics and allow students to test their understanding.
Lectures: 18 hours
Tutorials: 10 hours
Overall performance against all LOs in the module will be assessed by a 90 minute final exam, 6 questions, 100% weighting