Molecular Bioengineering (MEng)
Bioengineering Approaches to Cancer (UG)
- To equip students with an understanding of the fundamentals fo cancer development and progression.
- To develop a broad understanding of how engineering principles can be applied to the understanding and management of cancer.
Knowledge and Understanding
- Describe and explain the fundamental biological and biophysical processes involved in cancer initiation, maintenance, and progression
- Describe cancer processes using engineering, mathematics, and physical science methods
- Discuss the current methods of cancer treatment and diagnosis
- Understand current and future areas of bioengineering for understanding and managing cancer
- Communicate effectively with cancer biologists, oncologists and bioengineers working on cancer.
- Ability to teach complex topics to peers in other disciplines in an approachable manner
Introduction & Review of Cell Biology
Nature of Cancer
Signal Dysregulation I – RTKs and Ras
Signal Dysregulation II – Dual Address Pathways
Tumour suppressor genes
Cell cycle clock and pRb
Apoptosis and p53
Genomic Integrity & Cancer Progression
Cellular/Nuclear Biomechanics & Cancer
Transport Phenomena in Cancer
Screening & Imaging
3 Classical Pillars of Cancer Management
Biomarkers, Off-target Toxicity & Targeted therapies
Immunology & Immunotherapy
Latest Advances in Bioengineering for Cancer Research and Management
Introductory cell biology for example: BE1-HMCP Molecules Cells and Processes or equivalent. Speak to module leader about suitability if you do not have this completed.
Students will be taught over one term using a combination of lectures and study groups. Lecture sessions will be made available on Panopto for review and supplemented with technologies as appropriate to promote active engagement during the lecture such as 'learning catalytics'. Study groups will be based on taught content from lectures to reinforce these topics and allow students to test their understanding.
Lectures: 18 hours
Study groups: 4 hours
Journal club: 5 hours